No, I just noticed after a couple days at 6 caps that I felt lethargic overall (like many hours after dosing) and after 5-6 days, I could not take it anymore. Yes, just like MK-677 lethargy - exactly. I thought I may have 'had something', so I tried again a month later and the same thing happened. The third time, I went with 2-3 caps a day (two caps now that I think about it) for about 1.5 weeks, then added 1 more cap every 4-5 days. I had no lethargy at all with this dosing at all and next time I ran it - with a month break, I could go with 6 caps out of the gate with no problem. I would really try 2 x 1 caps for a week before adding another cap every 4 or so days. Hope that helps!