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New E-pharm product: URSOBOLIC !

Is it really gonna be available Monday?. I thought I read that somewhere in this thread. Well Henry did say next week, but I guess that could be any day next week. Monday is wishful thinking on my part.
 
Get this to UK as fast as possible please :D
 
henryv said:
Just noticed this photo on the facebook profile of one of our retailers:

Invalid Link Removed
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Looks good!

Now I just need a couple bottles of it and Testforce2 on my kitchen counter!

I see a Ursobolic - 7-spray - Testforce2 stack in my near future.
 
Cant wait to run this! Ill be getting at least 4 bottles ASAP. Think its a good product to run between cycles of any combo of Activate Xtreme, Triazole and/or bioforge? Or maybe too much aromatase inhibition all the time?
 
i see it, just wanting to see the reviews before i drop 40 bones.
 
henryv said:
It's sold out. You'll have to wait for one of the other retailers to list it. It wont be long.
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How many bottles did they get? 5? Why do they not show it OOS instead of making it invisible? That's so not cool.
 
houstontexas said:
Is this product better with any certain type of diet or does it work good with everything?
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I'd say by the looks of it a cut diet. As far as keto, low carb, high protein, I have no idea as of now.
 
houstontexas said:
How many bottles did they get? 5? Why do they not show it OOS instead of making it invisible? That's so not cool.
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They sold 100 in about two hours.

Orangatang said:
Highly extracted holy basil???
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It's not goddamn holy basil.

Rushi said:
When I say active here, I am referring to ursolic acid. There are other pentacyclic triterpene acids in there that may very well have similar activity.
Click to expand...

Yep. Oleanolic acid for one.

houstontexas said:
Is this product better with any certain type of diet or does it work good with everything?
Click to expand...

I dunno. It may reduce the digestion of carbs if it does function as a competitive alpha-glucosidase inhibitor.
 
MAxximal said:
wohaa so UA is like metformin :firedevil:
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In addition to suppressing hepatic glucose production, metformin increases insulin sensitivity, enhances peripheral Invalid Link Removed (by phosphorylating GLUT-4 enhancer factor), increases Invalid Link Removed,[SUP]Invalid Link Removed[/SUP] and decreases absorption of glucose from the Invalid Link Removed. Increased peripheral utilization of glucose may be due to improved insulin binding to insulin receptors.[SUP]Invalid Link Removed[/SUP]
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Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.
 
henryv said:
Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.
Click to expand...

Hmmm this sounds too interesting and I understand your point “of drug claims”.
another question did you know if UA is broken and metabolized by the liver or not?
I ask because I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)
 
henryv said:
Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.
Click to expand...

Hmmm this sounds too interesting and I understand your point “of drug claims”.
another question did you know if UA is broken and metabolized by the liver or not?
I ask because I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)
 
MAxximal said:
...I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)
Click to expand...

TTA may increase the effects, because it is a non-specific PPAR agonist, but I don't know if a) ursolic acid is only a PPAR-alpha agonist, or b) activation of PPAR-gamma contributes to the effects of TTA (Invalid Link Removed seems to indicate that it doesn't, if I'm reading it right). Edit: though if TTA increases beta-oxidation of fatty acids [Invalid Link Removed] it may help.

If HCA is an inhibitor of ATP-citrate lyase [Invalid Link Removed], and ursolic acid is an inhibitor of fatty acid synthase [Invalid Link Removed], then I would think the effects would be additive (in reducing the synthesis of fatty acids). Idk if that's a good thing or not.

As for Clarinol:

The effect of CLA consumption on fatty acid oxidation was also assessed. Compared with the control treatment, the CLA treatments did not affect changes in body weight, body composition, or blood lipids. In addition, CLA did not affect the β-oxidation rate of fatty acids or induce significant alterations in the safety markers tested. In conclusion, although no detrimental effects were caused by supplementation, these results do not confirm a role for CLA in either body weight or blood lipid regulation in humans.
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Invalid Link Removed

CONCLUSIONS:

CLA does not affect glucose metabolism or insulin sensitivity in a population of overweight or obese volunteers.
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Invalid Link Removed

There are a lot of different isomers in CLA and some have the opposite effects of others.

Bear in mind this is outside my field of knowledge, I'm just going off ten minutes of googling.
 
henryv said:
TTA may increase the effects, because it is a non-specific PPAR agonist, but I don't know if a) ursolic acid is only a PPAR-alpha agonist, or b) activation of PPAR-gamma contributes to the effects of TTA (Invalid Link Removed seems to indicate that it doesn't, if I'm reading it right). Edit: though if TTA increases beta-oxidation of fatty acids [Invalid Link Removed] it may help.

If HCA is an inhibitor of ATP-citrate lyase [Invalid Link Removed], and ursolic acid is an inhibitor of fatty acid synthase [Invalid Link Removed], then I would think the effects would be additive (in reducing the synthesis of fatty acids). Idk if that's a good thing or not.

As for Clarinol:



Invalid Link Removed



Invalid Link Removed

There are a lot of different isomers in CLA and some have the opposite effects of others.

Bear in mind this is outside my field of knowledge, I'm just going off ten minutes of googling.
Click to expand...


For the CLA I will use Clarinol or Tonalin (used in the study).
And this are the isomers of CLA:

Cis-9,Trans-11
Trans-10, Cis-12

And for all of the above you are correct!

When I got UA i on alpha test phase with my other goodies :firedevil:
 
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