New E-pharm product: URSOBOLIC !

[T-Bone]

Is it really gonna be available Monday?. I thought I read that somewhere in this thread. Well Henry did say next week, but I guess that could be any day next week. Monday is wishful thinking on my part.

 

[AtomicFox]

Get this to UK as fast as possible please

 

[dcne02]

It's Monday, any updates on availability?

 

[zb126]

Anyone find this in an online store yet?

 

[3clipseGT]

Anyone find this in an online store yet?

Ive been looking, but nothing as of yet.

Sent from my HTC Glacier using Tapatalk

 

[henryv]

Just noticed this photo on the facebook profile of one of our retailers:

 

[Feel The Burn]

Just noticed this photo on the facebook profile of one of our retailers:

Looks good!

Now I just need a couple bottles of it and Testforce2 on my kitchen counter!

I see a Ursobolic - 7-spray - Testforce2 stack in my near future.

 

[smallpecs]

Cant wait to run this! Ill be getting at least 4 bottles ASAP. Think its a good product to run between cycles of any combo of Activate Xtreme, Triazole and/or bioforge? Or maybe too much aromatase inhibition all the time?

 

[AdelV]

Just in time for my summer cut!

 

[Primal2]

its out at a certain store already. lockout

 

[houstontexas]

not seeing it bro...

 

[zb126]

Me neither....

 

[fightbackhxc]

i see it, just wanting to see the reviews before i drop 40 bones.

 

[dollar662]

dont see it either ..

Pm link ?

 

[MAxximal]

i see it, just wanting to see the reviews before i drop 40 bones.

wow $40?

 

[fightbackhxc]

wow $40?

Well you need two bottles, 21 a bottle.

 

[MAxximal]

Well you need two bottles, 21 a bottle.

Ufffffff I know it but I misread is $40 per bottle

 

[zb126]

You locked out of that site?

 

[dollar662]

I can get to the site and look under E-pharm but dont see it. It just list the other 4 products

 

[henryv]

I can get to the site and look under E-pharm but dont see it. It just list the other 4 products

It's sold out. You'll have to wait for one of the other retailers to list it. It wont be long.

 

[T50]

So $40 for a month supply?

 

[Primal2]

yes

 

[houstontexas]

It's sold out. You'll have to wait for one of the other retailers to list it. It wont be long.

How many bottles did they get? 5? Why do they not show it OOS instead of making it invisible? That's so not cool.

 

[louisaboy]

Got me a bottle... This stuff sold like hotcakes...lol

 

[Primal2]

its available on amazon now, just search ursobolic.

 

[Ginandtonic]

45$ for 30 days is pretty steep

 

[mattrag]

45$ for 30 days is pretty steep

Yea. I'm waiting for the logs on this one

 

[Orangatang]

What's the percentage of extracted Ursolic acid??

 

[Rushi]

What's the percentage of extracted Ursolic acid??

25% extract. Not sure of the source.

50mg active per cap.

 

[mattrag]

25% extract. Not sure of the source.

50mg active per cap.

Wow. So like 200mg per cap. Then the dosing is at 6 caps a day?

 

[Orangatang]

25% extract. Not sure of the source.

50mg active per cap.

Highly extracted holy basil???

 

[mattrag]

Highly extracted holy basil???

Hehe saw that on amazon as well. Holy basil and apples have something in common it seems.

 

[houstontexas]

Is this product better with any certain type of diet or does it work good with everything?

 

[mattrag]

Is this product better with any certain type of diet or does it work good with everything?

I'd say by the looks of it a cut diet. As far as keto, low carb, high protein, I have no idea as of now.

 

[Rushi]

Wow. So like 200mg per cap. Then the dosing is at 6 caps a day?

Suggested use is 9-18 caps daily, split up 3x and taken with food/lipid.

 

[Rushi]

25% extract. Not sure of the source.

50mg active per cap.

When I say active here, I am referring to ursolic acid. There are other pentacyclic triterpene acids in there that may very well have similar activity.

 

[mattrag]

Suggested use is 9-18 caps daily, split up 3x and taken with food/lipid.

That is a pretty high dose

 

[rip21]

Is this product better with any certain type of diet or does it work good with everything?

PA said he was drunk most of the summer and still leaned out so it may not matter what you eat.

 

[henryv]

How many bottles did they get? 5? Why do they not show it OOS instead of making it invisible? That's so not cool.

They sold 100 in about two hours.

Highly extracted holy basil???

It's not goddamn holy basil.

When I say active here, I am referring to ursolic acid. There are other pentacyclic triterpene acids in there that may very well have similar activity.

Yep. Oleanolic acid for one.

Is this product better with any certain type of diet or does it work good with everything?

I dunno. It may reduce the digestion of carbs if it does function as a competitive alpha-glucosidase inhibitor.

 

[EArch]

will NP be getting this anytime soon?

 

[MAxximal]

and UA affects leptin?

 

[henryv]

will NP be getting this anytime soon?

I think so.

and UA affects leptin?

Maybe. Maybe not.

 

[MAxximal]

I think so.



Maybe. Maybe not.

wohaa so UA is like metformin :firedevil:

 

[henryv]

wohaa so UA is like metformin :firedevil:

In addition to suppressing hepatic glucose production, metformin increases insulin sensitivity, enhances peripheral glucose uptake (by phosphorylating GLUT-4 enhancer factor), increases fatty acid oxidation,[SUP][89][/SUP] and decreases absorption of glucose from the gastrointestinal tract. Increased peripheral utilization of glucose may be due to improved insulin binding to insulin receptors.[SUP][90][/SUP]

Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.

 

[MAxximal]

Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.

Hmmm this sounds too interesting and I understand your point “of drug claims”.
another question did you know if UA is broken and metabolized by the liver or not?
I ask because I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)

 

[MAxximal]

Those look like some of the same MOA that ursolic acid is believed to work by, yes. See this thread:
http://anabolicminds.com/forum/company-promotions/183111-potential-benefits-ursolic.html#post3009190

We're not making any drug claims of our product, just informing you of the research that has been done on the ingredient.

Hmmm this sounds too interesting and I understand your point “of drug claims”.
another question did you know if UA is broken and metabolized by the liver or not?
I ask because I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)

 

[T-Bone]

45$ for 30 days is pretty steep

$45.40 plus $5.49 shipping. So $50.89 total for one month at the minimum recommended dosage I'm guessing. Yeah that is pretty steep. I hope Nutraplanet has a better price....

 

[T-Bone]

PA said he was drunk most of the summer and still leaned out so it may not matter what you eat.

Wow!, well that settles it than. I'm gettin me some Ursobolic!.

 

[henryv]

...I got some stacking options on my head :firedevil:

TTA (Tetradecylthioacetic Acid))
HCA (60% Hydroxycitric Acid)
CLA (clarinol brand)

TTA may increase the effects, because it is a non-specific PPAR agonist, but I don't know if a) ursolic acid is only a PPAR-alpha agonist, or b) activation of PPAR-gamma contributes to the effects of TTA (this study seems to indicate that it doesn't, if I'm reading it right). Edit: though if TTA increases beta-oxidation of fatty acids [link] it may help.

If HCA is an inhibitor of ATP-citrate lyase [link], and ursolic acid is an inhibitor of fatty acid synthase [link], then I would think the effects would be additive (in reducing the synthesis of fatty acids). Idk if that's a good thing or not.

As for Clarinol:

The effect of CLA consumption on fatty acid oxidation was also assessed. Compared with the control treatment, the CLA treatments did not affect changes in body weight, body composition, or blood lipids. In addition, CLA did not affect the β-oxidation rate of fatty acids or induce significant alterations in the safety markers tested. In conclusion, although no detrimental effects were caused by supplementation, these results do not confirm a role for CLA in either body weight or blood lipid regulation in humans.

http://www.ncbi.nlm.nih.gov/pubmed/21593349

CONCLUSIONS:

CLA does not affect glucose metabolism or insulin sensitivity in a population of overweight or obese volunteers.

http://www.ncbi.nlm.nih.gov/pubmed/17031391

There are a lot of different isomers in CLA and some have the opposite effects of others.

Bear in mind this is outside my field of knowledge, I'm just going off ten minutes of googling.

 

[MAxximal]

TTA may increase the effects, because it is a non-specific PPAR agonist, but I don't know if a) ursolic acid is only a PPAR-alpha agonist, or b) activation of PPAR-gamma contributes to the effects of TTA (this study seems to indicate that it doesn't, if I'm reading it right). Edit: though if TTA increases beta-oxidation of fatty acids [link] it may help.

If HCA is an inhibitor of ATP-citrate lyase [link], and ursolic acid is an inhibitor of fatty acid synthase [link], then I would think the effects would be additive (in reducing the synthesis of fatty acids). Idk if that's a good thing or not.

As for Clarinol:



http://www.ncbi.nlm.nih.gov/pubmed/21593349



http://www.ncbi.nlm.nih.gov/pubmed/17031391

There are a lot of different isomers in CLA and some have the opposite effects of others.

Bear in mind this is outside my field of knowledge, I'm just going off ten minutes of googling.

For the CLA I will use Clarinol or Tonalin (used in the study).
And this are the isomers of CLA:

Cis-9,Trans-11
Trans-10, Cis-12

And for all of the above you are correct!

When I got UA i on alpha test phase with my other goodies :firedevil: