sub
Yeah, we'd probably just release the 4-AD by itself so people could tailor its use. Its really a pretty cool steroid... very safe.Ooh, ooh -- how about a separate liqua vade product with 4-DHEA and formestane? It would stack great with 1-T. You'd have 1AD and 4AD, and the form would handle any aromitization issues from the DHEA (in 1-T) and 4AD. And (with DHEA, 4AD, and formestane), alpha maleness/libido would go through the roof.
It would also stack great with your SDlv, and any other cycles with libido or lethargy or gyno concerns (which pretty much covers all cycles, lol). Call it 4-T, and give me a few free bottles. Score.
Awesome. I've been missing 4AD for years -- it stacks well with anything. Sign me up...Yeah, we'd probably just release the 4-AD by itself so people could tailor its use. Its really a pretty cool steroid... very safe.
-Eric
I like this idea a lot. This would stack VERY well with Superdrol.Yeah, we'd probably just release the 4-AD by itself so people could tailor its use. Its really a pretty cool steroid... very safe.
-Eric
On PP forum it states that fura is a possibilty as long as supplier is available...so it does have a chanceAnd how is Furazadrol going? Is it going to have a chance?
When will you or think you will release the 4-AD?Yeah, we'd probably just release the 4-AD by itself so people could tailor its use. Its really a pretty cool steroid... very safe.
-Eric
Yes! I'll pray so that they find a supplierOn PP forum it states that fura is a possibilty as long as supplier is available...so it does have a chance
Me tooYes! I'll pray so that they find a supplier
Thats possible, probably within a few weeks of it being released from our site.Eric whats the chances some of these runs with be being shipped out to your european distributors (predator)?
Ours will be blessedSounds fantastic but Microdrol is available and you can easily manipulate the doses.
Yes, ours will be cheaper per mg than any other source.How will this compare price ranged with Microdrol, anything better or different you will have to per sway customer?
And so are we on for 4AD also?
Explain then...The whole idea of superior bioavailability is pure hype/marketing imo.
Go with capsules, you'll see the same result.
Liquid products suspend superdrol in a solution by using solvents that have similar polarity to superdrol. A solvent that is non polar will cause SD to dissolve when added into a solution. Most hormones are non polar molecules, the reason they are suspended in alcohol(s) is because alcohol(s) are also non polar, so the hormone readily dissolves (and that whole sterile thing too).Explain then...
What about the amount that is absorbed sublingually? Also, like I said earlier take away the liqua vade and it will still be better than most superdrol clones because Primordial Performance always uses high quality compounds and doses it exactly as advertised.Liquid products suspend superdrol in a solution by using solvents that have similar polarity to superdrol. A solvent that is non polar will cause SD to dissolve when added into a solution. Most hormones are non polar molecules, the reason they are suspended in alcohol(s) is because alcohol(s) are also non polar, so the hormone readily dissolves (and that whole sterile thing too).
Now, the environment of the stomach is very polar. It has to be, because HCl is polar, and without a polar environment/solvents you'd end up with solid hydrochloride instead of liquid hydrochloric acid, which would raise pH (lesser amount of free H+ ions) and leave us with one hell of an issue in terms of digesting foods.
In a non polar solvent (what is doing the dissolving), a polar solute (what is being dissolved) precipitates as a solid. The point? Like dissolves like. A polar substance dissolves in a polar solution, and vice versa. A polar solute does not dissolve in a non polar solvent, and a non polar solute does not dissolve in a polar solute.
So, while superdrol as liquid looks and sounds cool, it really doesn't matter. When it enters a polar environment (the stomach), the superdrol molecules precipitate out and forms a solid. You could take a liquid superdrol product, and dump it into water, and stir, and the superdrol would precipitate out to a solid, and you'd see exactly what I'm talking about.
I used to do something similar with Nolva (non-polar) from research suppliers to see how much Nolva had actually been dissolved into the vial. If you add it to water (polar), it precipitates out, and you can extract the solid, dry it, and weigh the stuff out to see if you got your moneys worth.
At the end of the day, your gonna get the same effect by taking capsules.
Even if it is (not that I'm saying it is)...see belowThe whole idea of superior bioavailability is pure hype/marketing imo.
Go with capsules, you'll see the same result.
Yes, ours will be cheaper per mg than any other source.
-Eric
Do it PLEASE. I'll snatch this up and kick start a T run so quick with this!Do you guys have any interest in this?
We are thinking about doing a limited time run...
-Eric
What about it? Transmucosal delivery is used to either a) improve drug delivery or b) deliver a drug when a patient cannot orally be administered the drug (vomiting, unconscious, etc.). The success of this route is dependent upon a variety of factors including the concentration of the drug, vehicle of drug delivery, mucosal contact time, venous drainage of the mucosal tissues (of which mucosal tissue has ample blood supply), degree of the drug's ionization and the pH of the absorption site, size of the drug molecule, and lipid solubility.What about the amount that is absorbed sublingually?
Says who? I hope that that is in fact true, but I've never seen any 3rd party testing of a PP product. Being the PH's aren't DSHEA compliant, I doubt PP is producing these products in cGMP facilities. I usually post over at the other forum, their products don't get a ton of attention over there, so this is really the first I've seen anyone mention them as having stringent QC measures in place. Their berry product does interest me though for overall health.Also, like I said earlier take away the liqua vade and it will still be better than most superdrol clones because Primordial Performance always uses high quality compounds and doses it exactly as advertised.
It may be the lowest price mg per mg of liquid solutions... but I'd be surprised if they can manufacturer for less than companies using capsules can.Even if it is (not that I'm saying it is)...see below
Any scientific evidence showing this "LV technology" is actually effective? I've never heard of it, nor do I have any idea what it entails... but if it's just another "liquid ph's are superior" campaign, then I beg to differ.and not to mention LV technology gets 2-3x better absorption so you can dose lower.
There have never been any studies done in regards to the kinetics of superdrol (which would definitively answer that question). Makes sense really... the scientific community doesn't give a fuuu. BUT, shelf life of SD will undoubtably be shorter when prepared as a solution vs powder.Whats the self life on SD, and LV products?
Maybe you can answer a question I've wondered about for a long time:Being that 17a molecules have no problems being absorbed orally, I see no reason why transmucosal delivery would yield better results or ever be considered for administration of 17a drugs.
No. No matter how you take a methyl it enters the blood stream and straight through the liver.Maybe you can answer a question I've wondered about for a long time:
I agree that sublingual absorption probably doesn't make methyls any more "bioavailable" than they already are. But, does the sublingual route bypass that "first pass" liver degradation, thereby decreasing hepatoxicity?
You are talking about a water soluble solvent (which quickly loose solvent capacity following dissolution). In the world of self emulsifying drug delivery systems (SEDDS) there is a water soluble co-surfactant, a surfactant and an oil. It creates oil droplets (micelles) which trap the active ingredient and enhance delivery by creating a finely dispersed emulsion (by a few different mechanisms)Liquid products suspend superdrol in a solution by using solvents that have similar polarity to superdrol. A solvent that is non polar will cause SD to dissolve when added into a solution. Most hormones are non polar molecules, the reason they are suspended in alcohol(s) is because alcohol(s) are also non polar, so the hormone readily dissolves (and that whole sterile thing too).
Now, the environment of the stomach is very polar. It has to be, because HCl is polar, and without a polar environment/solvents you'd end up with solid hydrochloride instead of liquid hydrochloric acid, which would raise pH (lesser amount of free H+ ions) and leave us with one hell of an issue in terms of digesting foods.
In a non polar solvent (what is doing the dissolving), a polar solute (what is being dissolved) precipitates as a solid. The point? Like dissolves like. A polar substance dissolves in a polar solution, and vice versa. A polar solute does not dissolve in a non polar solvent, and a non polar solute does not dissolve in a polar solute.
So, while superdrol as liquid looks and sounds cool, it really doesn't matter. When it enters a polar environment (the stomach), the superdrol molecules precipitate out and forms a solid. You could take a liquid superdrol product, and dump it into water, and stir, and the superdrol would precipitate out to a solid, and you'd see exactly what I'm talking about.
I used to do something similar with Nolva (non-polar) from research suppliers to see how much Nolva had actually been dissolved into the vial. If you add it to water (polar), it precipitates out, and you can extract the solid, dry it, and weigh the stuff out to see if you got your moneys worth.
At the end of the day, your gonna get the same effect by taking capsules.
You might want to checkout the reasearch done on Danazol (oral steroid). SEDDS technology enhances delivery over 200% -Being that 17a molecules have no problems being absorbed orally, I see no reason why transmucosal delivery would yield better results or ever be considered for administration of 17a drugs. There was a study done in 2004 using a buccal testosterone tablets enhanced with ingredients to aid in transmucosal administration comparing bioavailability to oral test und. The study showed success using the buccal testosterone preparation over oral test und, but other studies using methyltestosterone suggest that 17a oral testosterone is superior to the buccal testosterone tabs in terms of bioavailability.
When all is said and done, most of the time (99%) sublingual delivery is just another ploy to make consumers think they are buying a superior product.
If it ain't broke, don't fix it!!!
See my previous post.Says who? I hope that that is in fact true, but I've never seen any 3rd party testing of a PP product. Being the PH's aren't DSHEA compliant, I doubt PP is producing these products in cGMP facilities. I usually post over at the other forum, their products don't get a ton of attention over there, so this is really the first I've seen anyone mention them as having stringent QC measures in place. Their berry product does interest me though for overall health.
I bet we can... because we produce in our own in-house facility and don't have to pay turn-key contract manufacturing costs...It may be the lowest price mg per mg of liquid solutions... but I'd be surprised if they can manufacturer for less than companies using capsules can.
It will by-pass the "first pass" but it will eventually pass... so it doest really avoid toxicity.Maybe you can answer a question I've wondered about for a long time:
I agree that sublingual absorption probably doesn't make methyls any more "bioavailable" than they already are. But, does the sublingual route bypass that "first pass" liver degradation, thereby decreasing hepatoxicity?
Link doesn't work.Also, checkout an interview I did on SHR. I explain the whole technology in detail.
Damit your right... Ill ask Carl.Link doesn't work.
Microdrol is not using SEDDS (Liqua-vade) delivery technology. Its a good product for dosing small doses of SD, but its not going to be as potent as our SD Liqua-vade.Wouldn't this be just like microdrol?
I've been hearing that sam-E is the best liver protectant around. Agree?It will by-pass the "first pass" but it will eventually pass... so it doest really avoid toxicity.
I think the issue is to just address the toxicity by supporting the bile salt export pump (BSEP) to keep the steroids moving through the liver with something like silymarin. (which actually helps prevent 17a induced cholestasis) More info on this next week.
-Eric
Although it may help to normalize liver enzyme levels, I take 400mg daily more for mood support than liver support. An expensive, yet versatile supp.I've been hearing that sam-E is the best liver protectant around. Agree?
Wow, pre order yet Eric? My credit card is waiting...:booty:Microdrol is not using SEDDS (Liqua-vade) delivery technology. Its a good product for dosing small doses of SD, but its not going to be as potent as our SD Liqua-vade.
-Eric
I think the "liver longer" is a better product for steroid induced liver toxicity. The sam-e can help but has other unwanted side-effects if i recall.I've been hearing that sam-E is the best liver protectant around. Agree?
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