I have been out of the game for awhile so I guess there are new ways in doing things, but I have noticed here that you are advising the use of a steroidal AI in pct (forma-stanzol)? I know that suppression with formestane is dose dependent, but wouldn't you want to avoid any suppression in pct?
Yes you are correct it is
"dose dependent" and at a 5 pumps twice a day dose you are not getting anywhere near the rate which is needed to convert to a anabolic or cause any suppression. In order for there to be enough anabolic ativity to cause suppression you would need around 800-1000mg/day
Notwithstanding the fact that 4-hydroxyandrostenedione is also a weak prohormone to the anabolic steroid 4-hydroxytestosterone "As an aromatase inhibitor",
It still dominates with noteworthy testosterone stimulating properties. Any androgenic activity it may have (at dose dependent high levels) is more than compensated for by its unyielding capability to lower estrogen levels.
This action, of course, reduces the suppressive signal estrogen sends to your brain (estrogen is one of the main feedback signal to regulate the release of testosterone and also reduces skeletal growth by decreasing somatomedin levels reducing quick growth and quick recovery during pct),
thus significantly magnifying the testicular production of testosterone. In-vivo human studies show clearly that 4-hydroxyandrostenedione
will suppress estrogen concentrations at levels that were not high enough to suppress gonadotropins. Studies using 250mg to 500mg of 4-hydroxyandrostenedione injected every 2 weeks, or oral doses as high as 1000mg daily have
failed to show any notable suppressive effect towards testosterone concentrations.
On the contrary When formastane has been given to men, including oral doses as high as 500mg (well above forma-stanzols recommended pct dose), we have seen no measurable decrease to serm level testosterone and only a substantial increases in serum testosterone concentrations.
When used during pct after a cycle of prohormones, designer supplements or steroids forma-stanzol offers many exclusive and uncommon benefits .During PCT The main focus is to bring back testosterone as quickly as possible and minimize muscle lose well being in a hypoandrogenic state. During pct you no longer have a out side source of androgens well at the same time your body is also not producing its own androgens.
Most pct's consist of some kind of serm (estrogen blocker) and often a estrogen reducer if one were smart ( to reduce estrogen rebound and again further/re suppression ) This is because of ther effects estrogen blockers and Ai's have on testosterone release.
Formastane at the lower end of dosing will reduce estrogen which will intern increase testosterone. It will also bring progesterone/prolactin back to normal. formastane also lowers shbg and raises IGF significantly. Something that most if not all pct products or other serms on the market neglect when it comes to post Nandro compounds. All of which are great qualities to have in any pct and qualities that most serms and Ai's lack!!
Now Keep in mind Forma-stanzol is not "just" formastane.
Now Forma-stanzol also has
7,8 Benzoflavone a neuro-active flavone that passes the blood brain barrier and blocks the suppression of GnRH release through modulation of the GABAergic receptor complex. This also has posative nerotropic effects as well as posative effects on sex drive and feeling of well being. 7,8 benzo is also yet another powerful Natural Phytoserm.
Then we added Chrysin
Chrysin is a natural phytoserm that works much better when used topically. It is also able to stimulate nitric oxide release from endothelial cells leading to vascular cGMP accumulation and subsequent endothelium dependent vascular relaxation. Chrysin stimulated nitric oxide release is calcium independent and possibly mediated via PI3-kinase.Chrysin is able to suppress liposacharide-induced COX-2 Protein and mRNA expression in a dose-dependent manner. Nuclear factor for IL-6 has been identified as responsible for the Chrysin -mediated COX-2 downregulation.
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In other words it also helps your muscles absorb Protein and also gives better pumps in the gym and works as a serm.
Chrysin has one other property that could add to its pct potential. A major problem during pct is stress,anxiety, and mood due to unstable hormone levels. In a study published in Pharmacology Biochemistry and Behavior (1994), mice were injected with diazepam (Valium), chrysin, or placebo to evaluate the effects these substances had on anxiety and performance levels. Chrysin was shown to produce anti-anxiety effects comparable with diazepam, but without sedation and muscle relaxation (301). In other words, chrysin produced a relaxing effect in the brain, but with no impairment of motor activity. The mechanism of action of chrysin was compared to diazepam, and it was shown that unlike diazepam, chrysin can reduce anxiety without inducing the common side-effects associated with benzodiazepine drugs.
In other words Its like feeling so damn good its almost like you took a Valium
yet non of the bad side effects come with it.
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^^ you can refer to this study to see how both 7,8 benzo and chrysin are of the most powerful phytoserm flavones to date.
Froma-stanzol then adds diindolylmethane (dim) which some have given up on because of its poor bioavlablity however Diindolylmethane has a molecular weight of 246 and is oil-soluble compound. diindolylmethane is highly stable, doesn't need any conversion in stomach acid, and is by far one of the most active phytochemical to date. With the right delivery system this is very powerful stuff.
For you transdermal gear heads out there I was looking through my studies and I am sure you will like this
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Note even thinking about pct but right out the gate in needs to be noted that Diindolylmethane is the only molecule known in the biomedical field that has direct anti-cancer properties and immune modulating properties. However staying healthy can greatly effect recovery if you think about it. Also well we are on the subject steroids like testosterone are well known to impair the
immune system. Anabolic steroids reduce the amounts of immune
globulin A, G, and M in the blood. These proteins, known medically as IgA, IgG, and IgM, are part of the body's humoral immune system.
You may find it very interesting that Dim counteracts these effects to a degree
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Dim is naturally-occurring indole that affects the metabolism of chemical carcinogens. Researchers have also conclude DIM could play a critical role in the bodys response to environmental carcinogens!! With all the chemicals we are dealing with when it comes to cycles One could say this is some pretty good stuff to consider just for these reasons alone.
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Let me brake down another posative aspect in very simple terms so everyone can understand what DIM also does for the system.
DIM modulates Interferon-Gamma sensitivity by increasing the formation of its receptors on cell surfaces. What this means is that DIM forces the cells that are dangerous or harmful to health to be unable to hide from the immune system as effectively as they normally would, enabling the immune system to recognize them as unhealthy cells then attack and kill them. What is very fascinating and quite exciting is that DIM has absolutely no effect on normal cells. It simple helps the body recognize any unhealthy cells in the body so they can be found and destroyed .
virally infected cells are the ones that DIM helps to display more efficiently to the body's natural defense system leading to their destruction.
It almost works like a molecular alarm system alarming the body to where the problem exists so that the body can orchestrate its normal attacking mechanisms against such cells.
Now who in there right mind can say thats not perfect for on cycle or pct use ^^^ Thank you very much!!!
Moving on
testosterone converts to estrogen naturally then breaks down into "bad"and "good" estrogen metabolites. The
GOOD Vs bad ratio of estrogen metabolites is increased by DIM, thus resulting in lower bad estrogen metabolites and Higher good. This could also explain to a degree why Dim
increases the immune system and its response as we all know "good estrogen" is partly responsible for healthy immune system.
DIM blocks the estrogen, interfering with them at The ER. This raises the ratio of testosterone to estrogen. With DIM causing more testosterone to be freed.
Why dim works synergistic with formastane to make the perfect product for on cycle use as well as pct.
From an anabolic point of view, the level of free testosterone rises in the blood with use of diindolylmethane. The mechanism behind this is that 2-hydroxy estrogens have a greater binding affinity for the blood proteins that "lock up" testosterone in the blood. Thus, these plasma binding proteins instead latch on to 2-hydroxy, leaving greater levels of free testosterone, including that produced through the use of steroids and chemical hormones!
moreover The 2-hydroxy estrogens promoted by usage of DIM also increase testosterone synthesis through another mechanism. Estrogen, even more than testosterone itself, incurs a negative hormonal feedback loop to the pituitary gland, where the rate-limiting gonadotropin for testosterone synthesis, luteinizing hormone (LH) is synthesized and released. What this means is that high blood levels of estrogen, as may occur through aromatization of free testosterone, turn off the release of LH from the pituitary gland. This leads to a vicious biochemical cycle characterized by an imbalance between testosterone and estrogen in favor of the latter.
These events, however, are nullified by 2-hydroxy, which doesn't provide the negative feedback message to the pituitary induced by estrogen. The net effect is greater testosterone synthesis in the Leydig cells of the testes, as well as lower levels of bad estrogen and all the effects that go with it.
All of this ^^^^ this means a higher sex drive, better moods, muscle building , bone-strengthening , immune system boosting, synergistic enhancement of both natural and synthetic androgens ,and everything needed for good recovery or on cycle use.
Last In my formula I added a compound thats not very well known to the steroid world but its common in the Holistic health field.
Horse Chestnut Seed Extract
In holistic Medicine chestnut extract has been used for Poor blood flow in the veins, significant reduction in edema, and other health reasons. In fact, in Germany, more prescriptions are written for the oral, standardized horsechestnut extract as a treatment for
chronic venous insufficiency and or related circulatory problems than for any other drug or supplement
As for the mechanism of action,
the escin component (triterpene saponins) of horsechestnut extract acts by reducing capillary permeability to water, essentially helping to seal off the escape of water out of veins into the extravascular space. It has also been shown to improve tone of connective tissues within veins and block the breakdown of ground substance (proteoglycans), which provides important structural integrity to veins. Horsechestnut seed ingredients have been shown to inhibit the enzymes that break down these important proteoglycans and to inhibit lysosomal enzymes and hyaluronidase enzyme, both of which are known to break down tissue structure. Horsechestnut seed extract has also been shown to possess antioxidant properties. The combination of these effects accounts for the ability of this supplement to reduce localized edema and inflammation,
and increase venous pressure and flow. More recent studies indicate that aescin (extracted from horse chestnut seeds) may also possess anti-inflammatory effects useful in reducing swelling caused by excess fluid.
Horse chestnut extract in short pulls water out of the skin and pushes it into the veins and muscles. Locking/sealing it in cause better blood flow,thinner skin,thicker muscles,and everything associated with stronger veins/blood flow. you can literally feel it tightening up your skin within minutes of application and not long after feel its enhancing effects on veins and muscle blood flow.
Horse chestnut helps to strengthen your veins, which can prevent water retention and enhance vascularity. Your veins hold over 60% of your body’s blood volume, and their job is to carry that blood back to your heart. This means that they must be able to rapidly adjust to the increased demand for blood that occurs when you’re lifting weights. At this time, your body needs more oxygen and nutrients. To deliver these, your body increases its heart rate and thus the amount of blood it is able to eject. Your veins respond by stiffening to help deliver the oxygen-depleted blood back to your heart more quickly. At this point, the pressure forces some of the fluid out of your veins and into your body. This is a negative for bodybuilders because it creates a watery look and reduces your vascularity.
Horse chestnut, though, helps prevent this natural leakage by reducing the gaps in your vein walls.
Horse Chestnut Seed Extract
contains active saponins called escins. These compounds stimulate the pituitary gland to release the hormone called "adrenocorticotrophic" hormone (ACTH) directly into the bloodstream. This hormone in turn triggers the adrenal cortex to produce adrenal androgens including dehydroepiandrosterone (DHEA).
All in all my friend forma-stanzol is a unique product that can be used in many ways and you can bet our butt PCT is one of them. Thank you for bring this up and allowing me the chance to explain my self.