HRT - can be a lot of things - I believe in it, and have heard of HGH and natural Test as well as others (IGF-1), to bring up hormone levels that naturally decrease with age. A blood test can tell you at any age if you are in the normal range - though they all seem to have different definitions of normal. Roughly total Test should be at least 500, but the range goes up to 1200 when you are in your 20s and moves toward 800 are you get into your 50s and 60s, though it is very common for it to dip below the 500 level, and experience effects of low libido, and muscle loss, depression, etc. So HRT under a doctors care helps you get to the hormone levels you need to be able to feel good - and if you take good care of your self, weight training exercise, and clean diet - you can have the body of someone much younger - and have the energy to go with it. The studies I have read always say at the end - "we do not know the long term effects", so it is not without risk - but if you stay within normal healthy ranges, I think it is a great thing to do. The folks that abuse these hormones - dirving total test up over 4000 when they are in their 20s and need not assistance over the 1200 mark grow into freaks - but at a risk of addiction and other side effects and many feel that there are sever dangers to organ function. HRT is use not abuse - some will argue that there is a reason why natural hormones decrease with age - and it should not be messed with. I disagree.