Warning - Serotonin Syndrome
- Thread starter utk1976
- Start date
Kris
Board Supporter
I took Paxil for a little over a year. I quickly gained a ton of weight which promted me to eventually join a gym. Once I stopped taking Paxil I noticed the weight did not come off and I seemed to be alot weaker in the gym. After over a year of being off Paxil I still havent managed to regain the strength and endurance I had while on Paxil.
DobermanXXL
Member
Question: If one were to take an SSRI like zoloft for a period of time, and then eventually stopped the drug would they be back to feeling exactly like they used to? Or do these drugs have a long term effect, even when they're not used anymore?
DR.D
Well-known member
DobermanXXL said:
There is some evidence now to suggest long term "re-wiring" but I took SSRI's for almost a decade, and the effects where quite short term I can assure you. The day you stop taking it is the day you sense it's gone. As for adrenergics (like Dexadrine and Adderal), there is a good residual effect for sure though.
bioman
Well-known member
I've tried Cocamine and it was kind of hit or miss for me. I would either be put in a great, alert mood that helped work outs or it would over stimulate me and I'd be all edgey...which I thought was strange given that I'm a life long coffee drinker. Putting it in coffee definitely sends me over the top.
DR.D
Well-known member
MaDmaN said:
Where you been Madman? Good to see you around.
Just like Bio said, it's hit or miss. I think the PEA is the main factor in the erratic effects. Stacked with other adrenergic stims (like amphetamine, hordinine or ephedrine) that can act as MAOI's, the PEA is greatly potentiated. Otherwise, it's the mixed xanthines doing most of the work.
MaDmaN
Board Supporter
I just got some cocoa extract unsweetened of course from BAC...Im sure it has some health benefits other than mood enhancement..Thanks for the input Bio and Dr.D...I took almost a year off with the new baby and all it was a tough transition at first and I suffered severe anxiety worrying about the little guy which led to believe it or not postpartum depression.I guess it's not only for women I went on antidepressents prozac which ruined me then they switchd me to effexor.I could not stand the side effects and after 6 weeks I went off all meds.It has been almost a year and things are alot better and my little guy is the joy of my life...I do take St johns wort and N-Acetyl L-Tyrosine which seems to work well....
s.norman
Member
i just started taking 15mg meridia for weight loss and i'm also on 200mg zoloft for anxiety. i feel a little more anxious but it might just be fear of taking both together as it says that they do react. however you could take both zoloft and prozac and they don't interact. this makes no sense to me b/c prozac is a stronger ssri than meridia
BruFan
New member
Can't believe I found this forum, and this thread. Great stuff.
Quick question, my wife is on Welbutrin XL 150mg (slow release) and has just finished coming off Lexapro. I've told her she can't take the ECA stack I'm on... but now I'm thinking I might have been wrong.
Any problems with Welbutrin and the EC stack?
Quick question, my wife is on Welbutrin XL 150mg (slow release) and has just finished coming off Lexapro. I've told her she can't take the ECA stack I'm on... but now I'm thinking I might have been wrong.
Any problems with Welbutrin and the EC stack?
DR.D
Well-known member
BruFan said:
If she's only taking 150mg slow release/day, then she can probably get away with taking some EC too. Wellbutrin causes cardiac issues with me over 450m/d though and the E could result in nausea or palpitation. The C could contribute to shakiness. You could try it on her with a half dose of EC to see, then go to a full dose if that goes well.
BruFan
New member
Thank you for the feedback! Think we'll try a 10 E / 100 C for a couple of days (IF she stays on the diet and exercise with me first) and see how it goes. She's been watching my BF % dropping steadily and wanted in on it too (I JUST got her lifting last week) but I had nightmares of her Norepinephrine levels getting too high, and showing up in the ER having to hang my head and tell the docs that I pumped my wife full of a well known "evil" drug. :ntome:DR.D said:
Thanks again.
juiced!
New member
im suffering from depression, dropped off of long cycle, no post therapy, stupid i know. my doctor put me on wellbutrin xl for the depression and 200mg of tes. cyp. a week, does anyone know if anabolics have bad interactions with wellbutrin, wellbutrin effects dopamine not serotonin
dannyboy9
Banned
Sorry to hear about your bad experience utk1976. I don't know how long prior to your lunch you popped the caps and I'm not sure what the serving size is but the bottles of 5-HTP that I use have a serving size of 1 cap only so if you didn't stick with the serving size, you should.
Aside from that, you can try taking your serving during a meal and see how it settles on your stomach.
I've taken 5-htp on an empty stomach before and it didn't settle too well lol. Only thing is that it came out thru the backway, not my mouth lol
I don't know if it was a chemical reaction between the 5-htp and your anti-depressants but I would try the above if it concerns you.
Aside from that, you can try taking your serving during a meal and see how it settles on your stomach.
I've taken 5-htp on an empty stomach before and it didn't settle too well lol. Only thing is that it came out thru the backway, not my mouth lolI don't know if it was a chemical reaction between the 5-htp and your anti-depressants but I would try the above if it concerns you.
ottomaddox
Registered User
This post is over a year old.............................
dannyboy9 said:Sorry to hear about your bad experience utk1976. I don't know how long prior to your lunch you popped the caps and I'm not sure what the serving size is but the bottles of 5-HTP that I use have a serving size of 1 cap only so if you didn't stick with the serving size, you should.
Aside from that, you can try taking your serving during a meal and see how it settles on your stomach.
I don't know if it was a chemical reaction between the 5-htp and your anti-depressants but I would try the above if it concerns you.
thetimbomb
Member
Well I used to experiment alot, and still do. I took three zolofts. I was intensely happy, however I always felt like vomiting, although I never did. I was also very twitchy.
DR.D
Well-known member
dannyboy9 said:
Yeah, depression, allergies, headaches, etc.. I guess he didn't really give up on me. He just finally decided I was "cured" after about 10 years. (LOL) I've had many docs and still have one or two I see as needed now, but he was my main man. Find a good one and stick with him!
DR.D
Well-known member
CHAPS said:
I hear that bro. When using SSRIs, get on and get off as soon as possible. Don't try to milk them for years. The loss of libido can be even more depressing than the original depression! Celexa and Prozac were the cleanest in the sex department, and yohimbe can help with the anorgasmia. I much prefer the adrenergic anti-deps like Dexedrine.
thetimbomb
Member
yea. I also noticed that taking 3 zoloft increased my appetite like no other. wow it would be great on cycle! on a side note, I also have taken 6 wellbutrin before, 900mg total. That did absolutely nothing at all. ssri can play with your head, dont mess around
astrolifter
New member
I take effexor xr, and have also taken phenibut. Once, after taking several grams of phenibut, my whole face seized up, along with my upper extremities; during this time, my head involuntarily lowered, and I was unable to move it for about a minute or so. One of the scariest things i've ever experienced.
Fastflight
Member
Prozac destroyed my sex-life for months, even after stopping it.... now, a half year later on a mild test/hcg cycle,
prozac, being swapped for another amphetamine, it´s returning to normal again.
prozac, being swapped for another amphetamine, it´s returning to normal again.
NicoleHope
New member
Serotonin Syndrome does SUCK!
You are so lucky that it happened all at once. I was on lexapro and elavil at the same time an serotonin syndrome snuck up on me slowly. By the time the doctors figured out what was wrong 2 months later, I was having trouble balancing, I had a terrets like facial tick and my arms and legs were going numb. 2 weeks off the drugs and my symptoms have not returned to normal. 30 year old hottie reduced to a cripple at the folks house. DONT TAKE TWO AT ONCE! It sucks.
You are so lucky that it happened all at once. I was on lexapro and elavil at the same time an serotonin syndrome snuck up on me slowly. By the time the doctors figured out what was wrong 2 months later, I was having trouble balancing, I had a terrets like facial tick and my arms and legs were going numb. 2 weeks off the drugs and my symptoms have not returned to normal. 30 year old hottie reduced to a cripple at the folks house. DONT TAKE TWO AT ONCE! It sucks.
RipdnTxs2
Board Supporter
I,m on Zoloft 100mg and I have to be very careful with stims, like RPN, I can only take 2 at a time, anymore and I get heart palpatations, its that way with any stims since starting Z., I was on Celexa and never really had these effects with stims like with Z. I have been taking DS Lean Extreme and been have been feeling down, anyone know if there might be anything to this, being the cause. I HATE taking meds.....
Rodzilla
Board Sponsor
wow seriously? I take 100mg and seem to do fine with stims, thought I have not tried RPM
coolbreeze
Member
Human GI tract has many receptors for Serotonin hence getting sick and vomiting!
heavyduty
Member
also, as for the weight gain which is a big side effect, is it caused by and increase in hunger or a decreased metabolism?
Zero V
Well-known member
If all these products are for anti-depressants, then people are relying on medication to fix their problems to much. You know dehydration can cause depression? Not eating right can cause depression? because you imbalance your body. Learned that awhile back.
I went through a depression that pushed me to the point of dementia/mania, and I did crazy things(really I do know what its like to walk the beaches of insanity....) paranoid and everything....well after I got ahold of myself a little, life went to heck, and then my entire mind came undone. The result, after I pieced myself back together I am strong, and resiliant, and unaffected by my emotions compared to what I used to be(i still get sad and all at the right times)
Point is, like 90% of cases could be cured by fighting it yourself.
I once had OCD, and a couple of ticks(weird habits I would do repeatedly) and ADHD, I took them on in my own mind, fought wiht myself. made myself stand there and resist what I wanted to do until it drove me crazy. Its your body, tame it.
Medication only makes it worse in my belief, once medication works for you once, you always go back to it for every little prob.
I am not hammering people. I hope everyone can beat their feelings and live the happy life you all deserve. But do you really want to intrust your mind to a doctor? My mind is the only thing I can own that no one else can no matter what happens in the world.
I hope people who are suffering from this syndrome, and other kinds alike it recover fully.
But in a serious challenge of a question my friends, and i mean this to make you think.
If you cant claim your own mind, then what claim can you lay in life?
I went through a depression that pushed me to the point of dementia/mania, and I did crazy things(really I do know what its like to walk the beaches of insanity....) paranoid and everything....well after I got ahold of myself a little, life went to heck, and then my entire mind came undone. The result, after I pieced myself back together I am strong, and resiliant, and unaffected by my emotions compared to what I used to be(i still get sad and all at the right times)
Point is, like 90% of cases could be cured by fighting it yourself.
I once had OCD, and a couple of ticks(weird habits I would do repeatedly) and ADHD, I took them on in my own mind, fought wiht myself. made myself stand there and resist what I wanted to do until it drove me crazy. Its your body, tame it.
Medication only makes it worse in my belief, once medication works for you once, you always go back to it for every little prob.
I am not hammering people. I hope everyone can beat their feelings and live the happy life you all deserve. But do you really want to intrust your mind to a doctor? My mind is the only thing I can own that no one else can no matter what happens in the world.
I hope people who are suffering from this syndrome, and other kinds alike it recover fully.
But in a serious challenge of a question my friends, and i mean this to make you think.
If you cant claim your own mind, then what claim can you lay in life?
mrchristian
Active member
subbed
bingoliket
New member
Bumping this thread..
I'm on wellbutrin XL 150 mg every morning and sometimes stack it with 30 mg ephedrine and 200 mg caffeine which seems to work.
Sometimes I feel it lasts a bit longer than before I started taking Wellbutrin XL.
I have a question that I haven't found any answer to: Does anyone have any experience in taking GHB (recreational doses) while on Wellbutrin?
There isn't any info to avoid this in the rxlists around, but still - GHB/Xyrem isn't that common..
Also you are advised to avoid taking Tramadol when you are on this antidepressants. Does anyone have a clue if it's still possible to take them (I have some lying around, but better safe than sorry).
jgassen15
Member
just wait til you try coming off....brain shocks, intense fatigue, inability to think or retain information at all... still have problems from several psychiatric drugs when I was a young teenager..mainstream psychiatry is as alternative as it gets, highly experimental--don't know what the hell's going on.
i got into psychopharmacology because of all the stuff I went through when I was younger. When in doubt, don't jump on meds...Ever. Even if you are suicidal, without knowing what is truly going on in your brain you could easily exacerbate those feeling with psychiatric drugs. Like mentioned earlier, there are 1,000 different things that can make you depressed, and most often I believe it's the stress of everyday living that our primitive brain circuits just have a hard time adjusting to.
Chronic stress and corticosteroid activity retards neuron growth, neurons show less branching, messes with your hippocampus, and lowers FGF-2 which is shown to be low in people with anxiety and depression. That could also be why people have shown to have an improved sense of well-being on cort-blockers. '
David Healy has a great book on the myth of SSRIs in psychiatry and how they were originally thrown at people to be a masking agent for depression for pharmas to make money when they didn't have an adequate treatment for depression. I think any drug that works merely on one neurotransmitter system is just asking for trouble.
Think of it this way, would you take a drug to treat cancer that has a potential side effect of cancer?
i got into psychopharmacology because of all the stuff I went through when I was younger. When in doubt, don't jump on meds...Ever. Even if you are suicidal, without knowing what is truly going on in your brain you could easily exacerbate those feeling with psychiatric drugs. Like mentioned earlier, there are 1,000 different things that can make you depressed, and most often I believe it's the stress of everyday living that our primitive brain circuits just have a hard time adjusting to.
Chronic stress and corticosteroid activity retards neuron growth, neurons show less branching, messes with your hippocampus, and lowers FGF-2 which is shown to be low in people with anxiety and depression. That could also be why people have shown to have an improved sense of well-being on cort-blockers. '
David Healy has a great book on the myth of SSRIs in psychiatry and how they were originally thrown at people to be a masking agent for depression for pharmas to make money when they didn't have an adequate treatment for depression. I think any drug that works merely on one neurotransmitter system is just asking for trouble.
Think of it this way, would you take a drug to treat cancer that has a potential side effect of cancer?
Athletix
Board Sponsor
Yeah I see this happen quite often which is why I am completely opposed to the use of two concomitant antidepressants. You must have taken a lot though since Wellbutrin is mostly dopaminergic and has no action at serotonin receptors. Your Lexapro dose is completely normal as well. But yes that does actually sound like serotonin syndrome. In toxicological cases it is lower extremity myoclonus (jerking motions), diarrhea, sweating, and hypo or hypertension depending on how much you took. Glad you are okay.