@sns8778 I am very curious to know your thoughts on the Liposomal delivery system, and within that subset, sublingual vs capsule for a liposomal product. Is it always better / more bioavailable or is it just another / new way companies are selling products as "better"?
I first learned about it when I was inquiring about the effectiveness of Liposomal L-Carnitine,, but now I am starting to see it pop for pretty much all of the letter vitamins, magnesium, glutathione, etc.
I have several different thoughts on Liposomal delivery.
I think that for some things it can be good BUT I think in a lot of cases it's just a sales pitch and some companies use a lot of label deception and others are just outright lying about it to begin with.
For some ingredients, IF a company is using true Liposomal delivery, then I think it can be beneficial - but just like not everything is a good candidate for transdermals, not everything is a good candidate for Liposomes either.
^^^ The above though is a big IF on a lot of levels though because a lot of companies that are claiming to offer liposomal products are full of crap and what they're really doing is either just straight lying or using some creative labeling deception to trick people.
A true liposomal should be the active ingredient itself encased in a liposome which provides for an advanced delivery system.
I'm sorry, no offense to anyone that claims to use them or do this, but even very large raw material manufacturers with advanced very expensive equipment will tell you that this is a complicated process - whereas some companies act like its something super simple that they can do themselves. While in theory, one may could make a small amount of raw material into liposomal oneself with the right equipment, that doesn't mean that it will stay stable that way and be in the proper format by the time it reaches the customer. It also does not mean that one could do it on a commercial scale.
It's so difficult to do it and keep it stable that most raw material suppliers are only interested in doing it on things they can do metric tons of - like Vitamin C or Glutathione for example.
I'll give you an example - I don't discuss this much, but I've done consulting on the raw material side of the industry for 19 years and work with some of the largest raw material vendors in the world. Right now, I know of a company that has been working on a Liposomal/Phytosomal project and they, with a large development team, great equipment, and vast financial resources (50mil+ a year company) have been working on stability testing for over 8 months on this particular ingredient.
^^^ I use the above as an example of how ridiculous it sounds to me when some people try to make it sound like its so easy and they can do it themselves. Again, they may can do so on a small amount of grams, but they have no idea that its going to stay that way and it likely wouldn't by the time you received it.
Now, that leads me to an area that really just ticks me off that a lot of companies do and that's that they will trick people into thinking they're getting a liposomal or phytosomal ingredient. Companies will label a product and name it a fancy blend that has or implies liposomal or phytosomal in the prop blend name and then label it in a way that its actually a proprietary blend of just the ingredient and phosphatidylcholine, which is the ingredient used in the process to make a lipsomal ingredient.
Also, the next part - a lot of companies do this as a sales pitch but also to save money bc phosphatidylcholine is cheap so what you wind up actually getting may really be an underdosed amount of ingredient and the dosage looking higher than it is bc of the supposed phytosomal/liposomal delivery.
I hope that all makes sense.
For me, I would not buy a product with a supposed liposomal delivery unless it was something like Liposomal Vitamin C or Glutathione and even then, I don't think its needed for Vitamin C and I would only buy from a brand I absolutely trusted. Even on Liposomal Vitamin C and Glutathione, there are a lot of brands on Amazon that do what I mentioned above about the prop blend type labeling.