EvoMuse BMP - Body Modify:Phenotype Writeup

aver4581

Member
Awards
0
Did hypnosis to quit smoking day before starting bmp. Lets see how it goes. Interesting taste..
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Woke up and did a line of BMP to start the day. 5 minutes later my shirt split in half because I was so pumped.
The sad thing is, someone who doesn't know you are joking will probably read this one day after searching online and think you are serious and try it....or maybe that would just be funny and not sad? I don't know haha.
 

Rand0m

Member
Awards
1
  • Established
The sad thing is, someone who doesn't know you are joking will probably read this one day after searching online and think you are serious and try it....or maybe that would just be funny and not sad? I don't know haha.
I did another line at lunch and now my pants split. Instant calf gains.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Did hypnosis to quit smoking day before starting bmp. Lets see how it goes. Interesting taste..
Good luck with this man - you don't need that crap, it doesn't do anything to make your life better. I know you can win your freedom back :) Keep at it!
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I did another line at lunch and now my pants split. Instant calf gains.
OK, BRB- going to snort my entire bag now.
 

aver4581

Member
Awards
0
Really enjoying the bmp. Skin feels better and muscles feeling fuller. Today goes into week 7 waiting for the dcp im calling it a write off :(((. 3 weeks till my holiday sitting at 14%-15% bf
 

Rand0m

Member
Awards
1
  • Established
Been on BMP for 4 days but my muscles are feeling pretty full (like a carb pump). I haven't worked out since starting due to being so busy so that's a surprise. I get back on my regular rotation tomorrow so I'll be able to dose it preworkout. Still in a slight deficit for the rest of this month so I'm hoping for some strength/endurance effects.
 

aver4581

Member
Awards
0
Libido is now shooting up! Unfortunately im back on the death sticks :-(
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Is that with the tamper?
 

Rand0m

Member
Awards
1
  • Established
My last couple doses have been sticking to the roof of my mouth which hasn't been pleasant. I have everything to cap it but still lazy at the thought of it. So far it seems to be positively affect my strength but a little early to tell, hopefully it continues this week.
 

shockrock3

Well-known member
Awards
2
  • Established
  • First Up Vote
Sold out already...damn
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
I'm showing 12 left in stock.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Make that 11 :)...swear it said sold out earlier. Can't wait.
Been having some glitches this weekend. Probably overloaded with traffic.
 
DieselNY

DieselNY

Well-known member
Awards
3
  • Established
  • First Up Vote
  • RockStar
Am I the only person here that thinks that powder smells and looks like Ice-T Crystal Lite? I kinda like it
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
dsade - I think this was asked before, but any benefit in say, double dosing BMP? I believe at one point you were recommending 3 g/day. Does the final version just working better? Or did you drop a bulky ingredient that didn't do much? Just curious...
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Two scoops of bmp has me feeling gooood
I keep hearing this from a bunch of people. Can you expand on it? How does it make you feel? Relaxed? Stimmed? Alert?

Might have to try this.
 

josun

Active member
Awards
1
  • Established
I keep hearing this from a bunch of people. Can you expand on it? How does it make you feel? Relaxed? Stimmed? Alert?

Might have to try this.
Idk it's like a relaxed stim feel, it feels like I smoked some sativa honestly
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
dsade - I think this was asked before, but any benefit in say, double dosing BMP? I believe at one point you were recommending 3 g/day. Does the final version just working better? Or did you drop a bulky ingredient that didn't do much? Just curious...
Yeah, I ended up dropping the Aspergillus Awamori from the final formula. There were several reasons for it, though I still have it planned for another product down the road. Notably, we didn't have the necessary time to do the full safety evaluation and the capping procedure requires special breathing apparatus.

Still an ingredient that I am very excited about.

Anim Sci J. 2015 Mar;86(3):305-11. doi: 10.1111/asj.12281. Epub 2014 Dec 5.
Effect of feeding Aspergillus awamori and canola seed on the growth performance and muscle fatty acid profile in broiler chicken.
Saleh AA1, Hayashi K, Ijiri D, Ohtsuka A.
Author information
Abstract

The aim of this study was to examine effects of dietary supplementation with Aspergillus awamori and feeding canola seed on the growth and fatty acid profile in broilers. Twenty-eight chicks (15 days old) were assigned to the following groups: (1) control, fed a basal diet; (2) awamori, fed the basal diet supplemented with 0.05% A. awamori; (3) canola, fed a diet containing 5% canola seed; and (4) canola + awamori, fed the canola diet supplemented with A. awamori (seven birds/group). Body weight gain was increased by A. awamori but not influenced by canola seed. Breast muscle weight was increased in either awamori or canola groups. Although plasma triglyceride and cholesterol were decreased by feeding A. awamori or canola seed, fat content in the breast muscle were increased, accompanied by decrease in saturated fatty acids and increase in unsaturated fatty acids. Moreover, decreased thiobarbituric acid reactive substance and increased α-tocopherol content in the breast muscle was observed in all experimental groups. In conclusion, these results suggested that feeding canola seed and A. awamori might improve growth performance, and modified muscle fatty acid profile and α-tocopherol content, suggesting that they may improve meat quality.

© 2014 Japanese Society of Animal Science.
KEYWORDS:

Aspergillus awamori; broiler; canola seed; fatty acid; growth performance

PMID:
25773115
DOI:
10.1111/asj.12281

Biomed Res Int. 2014;2014:946859. doi: 10.1155/2014/946859. Epub 2014 May 4.
Integrative effects of feeding Aspergillus awamori and fructooligosaccharide on growth performance and digestibility in broilers: promotion muscle protein metabolism.
Saleh AA1, Amber K1, El-Magd MA2, Atta MS3, Mohammed AA1, Ragab MM1, Abd El-Kader H4.
Author information
Abstract

This study was conducted to show the effect of Aspergillus awamori (AA), fructooligosaccharide (FOS), and combined Aspergillus awamori and fructooligosaccharide (AA + FOS) on growth, digestibility, blood parameters, and expression of some growth-related genes. A total of 60 broiler chicks at the age of 15 d were divided into a control group (n = 15) and 3 treatment groups. The control group was fed a basal diet, and the treatment groups were fed basal diets supplemented with 0.05% AA, 0.05% FOS, and combined of 0.05% AA and 0.05% FOS. Results from measurement of growth performance and digestibility revealed a significant increase in the body weight gain with improved feed conversion rate in the experimental groups. Interestingly, dry matter digestibility (DMD) and crude protein utilization (CPU) were improved. In addition, plasma total cholesterol and low density lipoprotein-cholesterol (LDL-C) were decreased, while plasma high density lipoprotein-cholesterol (HDL-C) was increased by feeding AA, FOS, and AA + FOS. Expressions of growth hormone secretagogue receptor (GHSR), insulin-like growth factor 1 (IGF-1), and insulin-like growth factor 1 receptor (IGF1R) were increased in experimental groups. In conclusion, the supplementation of either Aspergillus awamori or fructooligosaccharide or both improves digestibility and growth performance probably by promoting skeletal muscle protein metabolism.

PMID:
24895630
PMCID:
PMC4026947
DOI:
10.1155/2014/946859
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Idk it's like a relaxed stim feel, it feels like I smoked some sativa honestly
So you took 2 heaping scoops?

With the osteomyelitis back I'm honestly in a whole lot of pain, and I won't be seeing my pain specialist for another 3.5 weeks. I have Kratom, that was pretty weak, so I've been looking to try anything for stress and pain relief.
 

josun

Active member
Awards
1
  • Established
So you took 2 heaping scoops?

With the osteomyelitis back I'm honestly in a whole lot of pain, and I won't be seeing my pain specialist for another 3.5 weeks. I have Kratom, that was pretty weak, so I've been looking to try anything for stress and pain relief.
Yea I took two big scoops. It will definitely make u happy lol
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Yea I took two big scoops. It will definitely make u happy lol
I'll give it a shot in the morning. Sometimes the salidroside keeps me awake and I have a huge day of orders tomorrow.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Yeah, I ended up dropping the Aspergillus Awamori from the final formula. There were several reasons for it, though I still have it planned for another product down the road. Notably, we didn't have the necessary time to do the full safety evaluation and the capping procedure requires special breathing apparatus.

Still an ingredient that I am very excited about.

Anim Sci J. 2015 Mar;86(3):305-11. doi: 10.1111/asj.12281. Epub 2014 Dec 5.
Effect of feeding Aspergillus awamori and canola seed on the growth performance and muscle fatty acid profile in broiler chicken.
Saleh AA1, Hayashi K, Ijiri D, Ohtsuka A.
Author information
Abstract

The aim of this study was to examine effects of dietary supplementation with Aspergillus awamori and feeding canola seed on the growth and fatty acid profile in broilers. Twenty-eight chicks (15 days old) were assigned to the following groups: (1) control, fed a basal diet; (2) awamori, fed the basal diet supplemented with 0.05% A. awamori; (3) canola, fed a diet containing 5% canola seed; and (4) canola + awamori, fed the canola diet supplemented with A. awamori (seven birds/group). Body weight gain was increased by A. awamori but not influenced by canola seed. Breast muscle weight was increased in either awamori or canola groups. Although plasma triglyceride and cholesterol were decreased by feeding A. awamori or canola seed, fat content in the breast muscle were increased, accompanied by decrease in saturated fatty acids and increase in unsaturated fatty acids. Moreover, decreased thiobarbituric acid reactive substance and increased α-tocopherol content in the breast muscle was observed in all experimental groups. In conclusion, these results suggested that feeding canola seed and A. awamori might improve growth performance, and modified muscle fatty acid profile and α-tocopherol content, suggesting that they may improve meat quality.

© 2014 Japanese Society of Animal Science.
KEYWORDS:

Aspergillus awamori; broiler; canola seed; fatty acid; growth performance

PMID:
25773115
DOI:
10.1111/asj.12281

Biomed Res Int. 2014;2014:946859. doi: 10.1155/2014/946859. Epub 2014 May 4.
Integrative effects of feeding Aspergillus awamori and fructooligosaccharide on growth performance and digestibility in broilers: promotion muscle protein metabolism.
Saleh AA1, Amber K1, El-Magd MA2, Atta MS3, Mohammed AA1, Ragab MM1, Abd El-Kader H4.
Author information
Abstract

This study was conducted to show the effect of Aspergillus awamori (AA), fructooligosaccharide (FOS), and combined Aspergillus awamori and fructooligosaccharide (AA + FOS) on growth, digestibility, blood parameters, and expression of some growth-related genes. A total of 60 broiler chicks at the age of 15 d were divided into a control group (n = 15) and 3 treatment groups. The control group was fed a basal diet, and the treatment groups were fed basal diets supplemented with 0.05% AA, 0.05% FOS, and combined of 0.05% AA and 0.05% FOS. Results from measurement of growth performance and digestibility revealed a significant increase in the body weight gain with improved feed conversion rate in the experimental groups. Interestingly, dry matter digestibility (DMD) and crude protein utilization (CPU) were improved. In addition, plasma total cholesterol and low density lipoprotein-cholesterol (LDL-C) were decreased, while plasma high density lipoprotein-cholesterol (HDL-C) was increased by feeding AA, FOS, and AA + FOS. Expressions of growth hormone secretagogue receptor (GHSR), insulin-like growth factor 1 (IGF-1), and insulin-like growth factor 1 receptor (IGF1R) were increased in experimental groups. In conclusion, the supplementation of either Aspergillus awamori or fructooligosaccharide or both improves digestibility and growth performance probably by promoting skeletal muscle protein metabolism.

PMID:
24895630
PMCID:
PMC4026947
DOI:
10.1155/2014/946859
Sounds very interesting. Wondering if this is part of the hung formula you were talking about.

So do you think it is worth experimenting with a double dose? Or do you not want to speculate in public?

So you took 2 heaping scoops?

With the osteomyelitis back I'm honestly in a whole lot of pain, and I won't be seeing my pain specialist for another 3.5 weeks. I have Kratom, that was pretty weak, so I've been looking to try anything for stress and pain relief.
Do you use agmatine at all? I am sure you may know this, but it seriously potentials opiods and other pain killers, and has some pain killing and anxiety reducing effects on its own. I believe it also reduces tolerance to some nsaids. I personally believe the mood enhancing and anxiety reducing effects are really the only direct method of pain killer - but we all know anxiety makes pain worse and we can cope better when we are calm.
 

shockrock3

Well-known member
Awards
2
  • Established
  • First Up Vote
So you took 2 heaping scoops?

With the osteomyelitis back I'm honestly in a whole lot of pain, and I won't be seeing my pain specialist for another 3.5 weeks. I have Kratom, that was pretty weak, so I've been looking to try anything for stress and pain relief.
Were you using the Red Vein Kratom strain? That one is supposed to illicit the most feeling of "relaxed" out of all of them.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Were you using the Red Vein Kratom strain? That one is supposed to illicit the most feeling of "relaxed" out of all of them.
I did the Maeng Da strain at 9+grams. It was alright, but still didn't quite cut it.

I do need to get some more bulk agmatine. I need it for the Demolish anyway, and I do recall it being pretty effective at potentiating the oxy. I can't really go any higher with my dosage, though, and keep being able to do anything remotely productive. Especially when I am in design/research finalization mode (Clear Edge and Demolish, aling with Skyn Fyrm) I have to be extremely clear or I lose the clarity of inspiration.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I did the Maeng Da strain at 9+grams. It was alright, but still didn't quite cut it.

I do need to get some more bulk agmatine. I need it for the Demolish anyway, and I do recall it being pretty effective at potentiating the oxy. I can't really go any higher with my dosage, though, and keep being able to do anything remotely productive. Especially when I am in design/research finalization mode (Clear Edge and Demolish, aling with Skyn Fyrm) I have to be extremely clear or I lose the clarity of inspiration.
My grandmother is using Fentanyl and Oxycodone for pain (she can barely get out of a chair and stand). She became mumbly and out if it and I was trying to tell my mom and aunt it was the opiates, but they wouldn't listen because the doctor said to do it. They just figured she was getting old and losing it. Then she wouldn't wake up and went to the ER.

I finally convinced the doctor to put her on 500 mg Agmatine 2x per day. She is now clear headed and using the smallest fentanyl patch available and a half of a 5 mg oxy pill twice per day. She hurts a little, but it definitely made them more effective and reduced side effects.

Too bad there isn't much more I can offer. .
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
My grandmother is using Fentanyl and Oxycodone for pain (she can barely get out of a chair and stand). She became mumbly and out if it and I was trying to tell my mom and aunt it was the opiates, but they wouldn't listen because the doctor said to do it. They just figured she was getting old and losing it. Then she wouldn't wake up and went to the ER.

I finally convinced the doctor to put her on 500 mg Agmatine 2x per day. She is now clear headed and using the smallest fentanyl patch available and a half of a 5 mg oxy pill twice per day. She hurts a little, but it definitely made them more effective and reduced side effects.

Too bad there isn't much more I can offer. .
I took a gram last night before bed, with the residual effect of the 12 hour release 10mg. I don't know what the hell happened but I jumped out of bed at 4am swinging and ready to fight. Before I realized that I had been dreaming I managed to twist my back up something fierce.

To make it better, I fell in the shower this morning. Trying as hard as I can to get moving, since we have a TON of orders from over the weekend but damn am I hurting bad today.

Gonna go ahead and drop another gram and take one of the instant release ones.
 

chedapalooza

Legend
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
I took a gram last night before bed, with the residual effect of the 12 hour release 10mg. I don't know what the hell happened but I jumped out of bed at 4am swinging and ready to fight. Before I realized that I had been dreaming I managed to twist my back up something fierce.

To make it better, I fell in the shower this morning. Trying as hard as I can to get moving, since we have a TON of orders from over the weekend but damn am I hurting bad today.

Gonna go ahead and drop another gram and take one of the instant release ones.
Feel better man!
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I took a gram last night before bed, with the residual effect of the 12 hour release 10mg. I don't know what the hell happened but I jumped out of bed at 4am swinging and ready to fight. Before I realized that I had been dreaming I managed to twist my back up something fierce.

To make it better, I fell in the shower this morning. Trying as hard as I can to get moving, since we have a TON of orders from over the weekend but damn am I hurting bad today.

Gonna go ahead and drop another gram and take one of the instant release ones.
Dude, you're your own worst enemy! You're a prize figher, vs. yourself! Try not to hurt yourself more man. We need those orders! haha.

With my grandmother, I told them to start at 500 mg 2X per day. After it seemed to be working, my mom decided to go to 500 mg 3X per day. I think it actually brought back some of the sides as far as my grandmother being out of it and such. So more might not be better.

I've also seen some studies that suggested taking the AGM maybe 15-30 minutes BEFORE the opiate dose was best. Not a lot of help when you're having breakthrough pain though and need relief.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
.

I've also seen some studies that suggested taking the AGM maybe 15-30 minutes BEFORE the opiate dose was best. Not a lot of help when you're having breakthrough pain though and need relief.
I had heard that about Cimetidine, but not Agmatine.

Side Note: I think I found a decent agmatinase inhibitor that I want to try out in the preworkout, or maybe even as a pain relief formula.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I had heard that about Cimetidine, but not Agmatine.

Side Note: I think I found a decent agmatinase inhibitor that I want to try out in the preworkout, or maybe even as a pain relief formula.
Very very interesting in the AGM inhibitor.

I've been doing a lot of Alzheimer's research and arginase inhibition seems to be promising. I have a theory that since Agmatine has brain protecting effects and provides a lot of the same functionality as arginine, it may be really good for AD patients too. Couple with an inhibitor, it could be super interesting.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Also, I'm surprised no one has taken a different approach to joint pain - increase blood flow, reduce pain perception...which Agmatine may help with. But everyone goes in the same direction.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Also, I'm surprised no one has taken a different approach to joint pain - increase blood flow, reduce pain perception...which Agmatine may help with. But everyone goes in the same direction.
I don't
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I noticed. That's why you could tell me to buy your special gasoline and drink it and I would get 3 bottles.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
I noticed. That's why you could tell me to buy your special gasoline and drink it and I would get 3 bottles.
It's got electrolytes.
 
GreenMachineX

GreenMachineX

Well-known member
Awards
4
  • Established
  • First Up Vote
  • Best Answer
  • RockStar
Also, I'm surprised no one has taken a different approach to joint pain - increase blood flow, reduce pain perception...which Agmatine may help with. But everyone goes in the same direction.
Increasing blood flow would also promote healing, aside from pain perception, correct?
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Increasing blood flow would also promote healing, aside from pain perception, correct?
Yes. A big part of the problem with Joint issues is they heal so slowly because blood flow is almost non existent. Nutrients get to the joint more through leakage through surrounding tissues than blood (at least that's my impression). Something that would increase flow would be better for healing. Glucosamine and chondroitin and most products in that light, IMO, don't even hardly get to the tissue that needs it
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Yes. A big part of the problem with Joint issues is they heal so slowly because blood flow is almost non existent. Nutrients get to the joint more through leakage through surrounding tissues than blood (at least that's my impression). Something that would increase flow would be better for healing. Glucosamine and chondroitin and most products in that light, IMO, don't even hardly get to the tissue that needs it
Yep, that's the problem with the osteomyelitis....no blood flow to the bones so the antibiotics have a tough tine getting in there.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
Yep, that's the problem with the osteomyelitis....no blood flow to the bones so the antibiotics have a tough tine getting in there.
I finally got a second to look up osteomyelitis ....I am sorry to hear you have that Matt. Sounds unbelievable.

I can't imagine how you would increase blood flow to bones...but my first thought is to modify marrow? Kind of ironic that bones create our blood and then don't get much of it after the fact.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
I finally got a second to look up osteomyelitis ....I am sorry to hear you have that Matt. Sounds unbelievable.

I can't imagine how you would increase blood flow to bones...but my first thought is to modify marrow? Kind of ironic that bones create our blood and then don't get much of it after the fact.
I can't imagine how much worse it would be without the BMP, honestly.

I'm working on the blood flow issue right now, mostly for the preworkout but funny how that personal motivation kicks your ass into gear.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I can't imagine how much worse it would be without the BMP, honestly.

I'm working on the blood flow issue right now, mostly for the preworkout but funny how that personal motivation kicks your ass into gear.
Yeah, I am not directly effected, but I have a close family friend who recently developed Alzheimer's and I started reading hundreds of studies. And I am sorry to say that I see signs that the pharmaceutical companies may not be trustworthy with our health. Sometimes it may be best to take it into your own hands.
 
dsade

dsade

NutraPlanet Fanatic
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
Yeah, I am not directly effected, but I have a close family friend who recently developed Alzheimer's and I started reading hundreds of studies. And I am sorry to say that I see signs that the pharmaceutical companies may not be trustworthy with our health. Sometimes it may be best to take it into your own hands.
That's kind of what got me into this business to begin with, trying to recover from being hit by a drunk driver after my back was already screwed up by Army Malpractice.
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
That's kind of what got me into this business to begin with, trying to recover from being hit by a drunk driver after my back was already screwed up by Army Malpractice.
I hate to be a conspiracy theorist - and I'm not sure there is an intent on the individual level - but the system is just a mess. Doctors can't do anything outside the box because if they do anything, they have to be able to point the finger at someone else to say, "This is industry standard". So if you have an incurable disease, you can't try something that "might" help because it is not proven. Plus, they really get their training from other doctors and pharmaceutical company propaganda. They are basically mechanics, "If this symptom comes up, you use this tool (drug) to treat it."

And pharmaceutical companies can only make a profit on specific, non-natural products. So in the case of AD, resveratrol may be promising, but they don't want to prove that resveratrol can have an impact because they make no money at that - but they do want to study resveratrol to see HOW it works and create a drug that works on that ONE pathway, synthetically, that can't be had naturally. I read a long time ago that if aspirin was discovered today, pharmaceutical companies would not release it because it doesn't fit their drug model of today. I understand that now and agree. They want drugs that do one thing, one thing only, and don't cascade into other areas. I see the purpose of this for limiting liability, but it eliminates potential uses that actually fix problems.

Add into that the fact that there is so much government regulation, insurance interference, etc. - and it's just a mess.

As far as the AD, in 2014 Duke University conducted a study that showed that rats given DMFO (an arginase inhibitor used to treat cancer) showed signs of the reversal of Alzheimer's symptoms. This suggests an arginine deficiency is at play, which is the first time we've actually had some kind of pathology for the disease instead of just trying to treat symptoms. There have been a couple more studies that fit in with this study over the past 2 years - such as a recent study that shows the amyloid plaques and tau proteins in the brain may actually have antibacterial activity. This, to me, suggests the apparent symptoms are actually a response to an underlying cause - arginine deficiency fits this model as many forms of bacteria simulate arginine deficiency by releasing arginase, and arginine deficiency itself will lead to increase ammonia build up. The studies fit together suddenly - but there was a study in 1998 pointing in this same direction that appears to be completely ignored, I'm guessing because the conclusion was that we can impact AD by implementing the same guidelines and treatments we use for cardiovascular health, which means no new drugs, no new cures, no new treatments. It seems to have been missed, or ignored, for 16 years.
 

chedapalooza

Legend
Awards
4
  • RockStar
  • Legend!
  • Established
  • First Up Vote
I take agmatine daily and have horrible chronic myalgia and joint pain..
 
HIT4ME

HIT4ME

Well-known member
Awards
4
  • RockStar
  • Established
  • First Up Vote
  • Best Answer
I take agmatine daily and have horrible chronic myalgia and joint pain..
Not surprising. It isn't a powerful pain killer. It is a slight pain killer, and like I said I think the anxiolitic effects account for the pain reduction - you are calmer so you deal with the pain better. It won't eliminate pain, but is your pain slightly worse when you don't take it for long periods? I bet you would be surprised.

And if you take pain medication with it, the pain medication will work better than it would if you weren't using Agmatine.
 

Similar threads


Top