Something I posted for our reps- I will put it up here as well:
Couple quick reads on how the Lit-Up formula minimizes any type of potential side effects from D-Aspartic Acid:
http://ceu-usa.com/courses/WC001/test_drive/methylation_cycle.htm
http://hopes.stanford.edu/n3619/drugs-supplements-treatments/disease-mechanisms-and-drugs-target-them/inflammation/folic-acid
http://www.chronicfatiguetreatments.com/wordpress/treatments/methylation-cycle-block-theory-chronic-fatigue-syndrome/
This is why some people get depressed or anxious on regular DAA products- DAA activates the NMDA receptor, and NMDA activation, while ok in itself, is not good in excess. When homocysteine begins to build up (it is a by-product in the SAM-e cycle), it can actually cause additional excess activation in the NMDA receptor. This can lead to a lot of the sides you are hearing about from DAA, such as anxiety, depression, and night sweats. However, homocysteine has two routes of disposal- and this is the beauty of the formulation:
1. It can accumulate and be disposed of in the urine
2. It can be transformed (re-methylated) into methionine by folic acid, where it can re-enter the SAM-e cycle and be used again.
As you can see in the articles, Folate, TMG, and B-12, are all substrates that help to increase step 2- and this is why you will see few, if any DAA-related sides from Lit-Up- the product contains agents that re-methylate homocysteine, thus preventing any type of build-up in the tissues and keeping it from overloading the NMDA receptor....