BMP™ Improved Formula Presale

Ricky10 said:
Was it ever explained why Sinomenine and Quercetin were added to the formula? Essentially a pro-histamine and an anti-histamine at odds here. Quercetin is commonly known to not be all that bioavailable though...so the the Sinomenine would win. I am not sure if the dihydrate form resolves the bioavailability issue though. Apparently not enough for some people in this thread anyway.

Edit: Oh, I just saw that the goal is to inhibit the P-glycoprotein efflux pump with these ingredients...
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The Sino is included presumably because it is a potent P-gp inhibitor, among other things, but it could exacerbate allergies because of it's histamine releasing properties. Also, anyone on serotonergics or SSRIs might have greater odds of allergic response with mast cell involvement. Hives basically.

But something else might be going on, and the tattoo thing seems like a clue. Tattoos are not permanent, but more like temporarily permanent, because they are conveyed by macrophages that die and give their ink to new ones (that's why tatts blur over time.) BMPs induced expression of pro-inflammatory iNOS and TNF-a so inflammation is to be expected, and macrophages also have BPM receptors. BMP-6, for example, is known to regulate the proliferation and gene expression of macrophages, and so increased macrophage turnover might explain the '3-D effect' as the region could become overcrowded transiently by increased macrophage activity.

Basically, it may promote various forms of dermal inflammation in some, but there's no reason to believe it's auto-immune. The first thing I'd try is taking a low-dose antihistamine (just enough to stop the hives, no more) or maybe reduce the dose of BMP to see if that resolved the sides.
 
So I went back off BMP yesterday and today I can say that my rash has gone away almost completely. I might startup BMP again next week and see what happens. It's starting to become more likely that my rash was caused by BMP.
 
I am going to pay more attention to the timing, but I seem to think I get lethargic and sleepy after taking a dose :sleep:
 
The Solution said:
I have been on BMP almost 3 weeks.
Honestly, I got nothing from this product at all during the entire run
No improvements on anything (Mood, energy, strength, recovery).
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Explain more, how you have taken it? Maybe your body already on optimum form?
 
00A said:
Explain more, how you have taken it? Maybe your body already on optimum form?
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I have an entire log in the supplement log section.
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if i gave BMP to some obese individual and had them walk on a treadmill does that mean it automatically works? No

A supplement should work as claimed for any trainee. That is why there is a "Write-Up" outlining what to expect and the benefits of taking a product. Sure there will be people who do not respond to certain formulas or ingredients, but "Optimum" form is a far cry of being accurate since I am 20+ pounds over stage weight and train and eat just like everyone else on here who follows a consistent diet and training program.
 
The Solution said:
I have an entire log in the supplement log section.
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if i gave BMP to some obese individual and had them walk on a treadmill does that mean it automatically works? No

A supplement should work as claimed for any trainee. That is why there is a "Write-Up" outlining what to expect and the benefits of taking a product. Sure there will be people who do not respond to certain formulas or ingredients, but "Optimum" form is a far cry of being accurate since I am 20+ pounds over stage weight and train and eat just like everyone else on here who follows a consistent diet and training program.
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I missed that, intresting read, guess try CEL AE next!!
 
BigGame84 said:
Now that my rash has gone away, I’m giving BMP one more chance. Let’s see what happens.
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If this were me I would take 1 pill 2X per day and see how you tolerate it.
 
Ricky10 said:
Very possible, but I had the opposite response from the prior formula that was in the pouches..
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It's an adaptogen and like any adaptogen some get tired from it, some get the opposite, and some just sort of get a more calm neutral focus. My only guess as to why you would.
 
Currently on week 3 going into week 4 and what I have noticed is cardio related. When I run my actual skeleton feels stronger. Its quite a nice feeling.
 
Danksta710 said:
Currently on week 3 going into week 4 and what I have noticed is cardio related. When I run my actual skeleton feels stronger. Its quite a nice feeling.
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Haha that’s a pretty interesting feeling
 
Danksta710 said:
Currently on week 3 going into week 4 and what I have noticed is cardio related. When I run my actual skeleton feels stronger. Its quite a nice feeling.
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Haha that’s a pretty interesting feeling
 
Today I took 2 capsules 30 minutes before my workout and did not experience any lethargy. This was my first time doing a PWO dose and I definitely feel like my pump and fullness was enhanced. Strength and endurance seemed up to par, and I did have to rush things as my gym closes early on Saturdays.

On top of that, somebody had the nerve to talk to me so I was thrown completely out of my zone!

Note, this is also my first day of PCT, so I was happy to be looking so full and have such a nice pump going on!
 
Danksta710 said:
It's mostly cardio in the woods too so nice rough terrain. BMP is making those runs less taxing. That alone makes this product worth something for me. Looking forward to more benefits.
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Salidroside and EPO. One of the main reasons this was a key ingredient in CardioTryx.

I'm rewriting the BMP writeup with all of the immense new info on BMPs. The original writeup was early on, and needs a HUGE update. Apparently, though, my writeup guy has completely wiped himself off the face of the Earth, so I'm squuezing it in as I can.

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Posted on FB, forgot to post here.

Note that the study didn't show that BMP signalling was A signal in hypertrophy, but THE dominant signal.
Indeed, two independent groups have shown that BMP pathway, acting through Smad1/5/8, is the fundamental hypertrophic signal and dominates Myostatin signalling. Moreover, BMP-Smad1/5/8 negatively regulates a novel ubiquitin ligase, named MUSA1 that is required for muscle loss.
VERY close to announcing the MyoSynergy advance that we'll be releasing soon. A combined BMP/MyoSynergy protocol will be incredible.


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BMP 2/4/7 and Osteoarthitis - linked with Myostatin

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dsade said:
Posted on FB, forgot to post here.

Note that the study didn't show that BMP signalling was A signal in hypertrophy, but THE dominant signal.
Indeed, two independent groups have shown that BMP pathway, acting through Smad1/5/8, is the fundamental hypertrophic signal and dominates Myostatin signalling. Moreover, BMP-Smad1/5/8 negatively regulates a novel ubiquitin ligase, named MUSA1 that is required for muscle loss.
VERY close to announcing the MyoSynergy advance that we'll be releasing soon. A combined BMP/MyoSynergy protocol will be incredible.


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Really looking forward to MyoSynergy!
 
GreenMachineX said:
Really looking forward to MyoSynergy!
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I'm going to be out most of the week with kidney stone recovery, but hoping to start testing the week after.
 
The Solution said:
When do you think you will be able to put together Slintensity V2?
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I'm doing a bioavailability experiment on one of the new ingredients. It has a small dosage area that seems to activate GLUT4 only in muscle, while dosing too high activates GLUT4 non-specifically. Trying to find that sweet spot.

It's making a lot of sense, really, as muscle specific GLUT4 activation would be initially preferable and would only activate adipose GLUT4 in circumstances of massive over intake of carbs.
 
Been back on BMP since Saturday. 4 caps/day. No sign of any rash at all. So I’m going to say that my rash last week had nothing to do with BMP.
 
BigGame84 said:
Been back on BMP since Saturday. 4 caps/day. No sign of any rash at all. So I’m going to say that my rash last week had nothing to do with BMP.
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Cool! Still taking Stano-Plex too?

I can’t remember if you are also taking Anabolic Effect?
 
Ricky10 said:
Cool! Still taking Stano-Plex too?

I can’t remember if you are also taking Anabolic Effect?
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Yes. 900mg of the Stano-Plex.

I do have 2 bottles of Anabolic Effect but waiting to use those after the Stano Plex.

Also in the mail, I got the new formula of Hydra Head Six. Not sure what the label is but will post it when I receive it, either tomorrow or Thursday.

Anyways, glad I can continue on with BMP. Have 3 more bottles in my arsenal.
 
BigGame84 said:
Yes. 900mg of the Stano-Plex.

I do have 2 bottles of Anabolic Effect but waiting to use those after the Stano Plex.

Also in the mail, I got the new formula of Hydra Head Six. Not sure what the label is but will post it when I receive it, either tomorrow or Thursday.

Anyways, glad I can continue on with BMP. Have 3 more bottles in my arsenal.
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Gotcha. Yes, I saw HH6 was being reformulated. The former one was my favorite natty anabolic in recent years...undeniably effective supplement. Maybe BMP will become my new favorite though....we shall see!
 
I am going to start a Halodrol Cycle next week (6 week cycle) and use BMP with it (for the next 4 months at least), I know it will potentially be hard to tell if the BMP is helping at all, but I have done a couple Halodrol Cycles and know what to expect. (I love it)

Excited
 
According to Facebook, new myosynergy elite testing starts soon. I never had the opportunity to try the original. Looking forward to giving it a shot in combination with BMP
 
I just wanna drop by and confirm that for the past week and a half there has been no itchyness or Raised skin on my tattoos, I currently have No adverse side effects of BMP. I'm still on bottle number one! I never took any break, those effects subsided with time!!


Quick question though for the Calcium Pre Workout!

I have been taking a tums as mentioned, now that I'm using BFF VasoBlitz that includes 2g of Calcium Lactate do I still take the Tums? Or is that good? Thanks a lot!
 
That's a lot of Calcium. I would just stick with the 2g
 
Anyone else tried all preworkout? I've done it twice now and the pump is intense, is it more effective in the long run at split dosing or does it not actually matter too much?
 
Sparta12 said:
Anyone else tried all preworkout? I've done it twice now and the pump is intense, is it more effective in the long run at split dosing or does it not actually matter too much?
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Generally it would be less effective, though the acute effects are pretty great.

You would get better long term effects keeping with the split dosing.
 
Sparta12 said:
Anyone else tried all preworkout? I've done it twice now and the pump is intense, is it more effective in the long run at split dosing or does it not actually matter too much?
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I will say preworkout I personally really feel it as well. Everything just gets a boost, lifts, endurance, pumps etc.
 
I am 3/4 way thru my first of three bottles and everytime I take it about an hour after my toes feet and ankles get extremely itchy to the point I can’t stand it anymore and going to have to discontinue use. Nothing else has changed in my routine diet or supplementing besides BMP. Anything you can think of to try and do to combat or just probably not the right product for me? Thanks
 
alanhouston90 said:
I am 3/4 way thru my first of three bottles and everytime I take it about an hour after my toes feet and ankles get extremely itchy to the point I can’t stand it anymore and going to have to discontinue use. Nothing else has changed in my routine diet or supplementing besides BMP. Anything you can think of to try and do to combat or just probably not the right product for me? Thanks
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DO you have nerve damage/neuropathy, etc in your extremities? It's possible that your body is repairing damaged/less than ideal functioning nerves.


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No injuries to report. I’m fully healthy and 30 years old. No rash and have been trying not to itch but I’ve had poison ivy twice and it’s like that feeling just more intense. It’s almost like I dumped topical beta alanine all over my feet and let it soak in. Have taken pre wo with and without BA because I thought maybe that had something to do with it and it’s no change one way or other. It’s weird that this started popping up 10 or so days after I started taking it but the last week has been rough and I gotta stop. Feel like the product is good though besides that side effect.
 
Have you been using a public shower or pool?
 
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