Ptlhains
Active member
Has anyone noticed increased anxiety?
Yes...it went away at about 1.5-2 weeks. How many days / weeks are u?
Has anyone noticed increased anxiety?
I need to get my hands on this.![]()
When you get to the point where you can consciously cycle between the two, you try to reach a point where you can "kind of" see both at the same time.
Once you are able to do this, grasshopper, it will be time for you to leave.
Invalid Link RemovedHi Matt, don't mean to de-rail the thread but what exactly do you mean by that?
I always try to balance smart business (which I pretty much fail miserably most of the time) with taking care of customers going through rough times. If you're up for running a 2 month log, I'll kick in the BMP.Things are tight now, but it’s on my to do list haha
@dsade ooohhhh if you need a guinea pig like that, I'm your guy! Next weekend will be my last of the "summer stretch" (which had more drinking and travel - not just my usual weekly work travel, but weekends too) and im heading into my typical fall building season but the last 3 years trying not to just bulk because I had historically yoyo'd my weight waaayyyy too far and then had to do a dramatic cut in the spring just to get back to something shirtlessly acceptable... I could also add in the bottle I have already to extend it to 3 months if that adds to the enticement (not running anything else either)I always try to balance smart business (which I pretty much fail miserably most of the time) with taking care of customers going through rough times. If you're up for running a 2 month log, I'll kick in the BMP.
Looking for someone who's trying to recomp (gain muscle/strength while losing fat), so training needs to be intense and incrementally increasing with slight caloric/protein elevation.
Hey@dsade Any follow up as to why the label on the new BMP does not match the dosages you initially listed on this thread?
In your original post, you listed the new and improved formula to be this:
-Kaempferol Cyclodextrin Complex 75 mg
-Rhodiola Rosea (std for Salidroside 8%) 240 mg
-Osthole Cyclodextrin Complex 100 mg
-Ligusticum Wallichii Extract (std for 98% Ligustrazine) 100 mg
-Sorghum Extract 100:1 200 mg
-Paeoniflorin 100 mg
-Quercetin 200mg
-Sinomenine 100mg
....Yet my bottles say this:
Kaempferol Cyclodextrin Complex 70 mg
(5 mg less then what was stated)
&
Sinomenine 75mg (25 mg less the n stated)
Every other ingredient is listed at correct dosages from original post. I'm not complaining as I'm loving my run of the new BMP, I was just curious as to why they are different.
Got it, thanksHey
Production chimed in above...the label is correct, the writeup was incorrect.
Yes...it went away at about 1.5-2 weeks. How many days / weeks are u?
Well, my post was meant for you. If you're up for it, I'm game.I am currently slowly gaining, but will probably look to hold steady through October at new heavier weight. (if that counts as “recomp”).
My training is not the typical bodybuilding or bro style. More CrossFit, although I doubt what pops into most people’s minds when I say that would reflect what it is truly like.
I can give more info if needed about it, but training is intense and very structured.
If this falls into the conditions you would like I’d be honored to try my best to log this as best I could.
Already following your log....I am currently slowly gaining, but will probably look to hold steady through October at new heavier weight. (if that counts as “recomp”).
My training is not the typical bodybuilding or bro style. More CrossFit, although I doubt what pops into most people’s minds when I say that would reflect what it is truly like.
I can give more info if needed about it, but training is intense and very structured.
If this falls into the conditions you would like I’d be honored to try my best to log this as best I could.
If anything, I have been more sensitive to caffeine (thus finding it more effective) than usual - so BMP may be doing this. I think you need to regulate this yourself based on other factors - such as - are you getting a good sleep.Week 6 or 7.
I know this supp makes people who use nicotine more sensitive to it. I drink a lot of caffeine. Do you guys think BMP might be making that more effective and I should lower the caff? Loving the BMP. I feel and look tight. Cardio in the woods is still awesome. Still got that strong skeleton feeling going on. Almost feel like a Terminator ;-)
If anything, I have been more sensitive to caffeine (thus finding it more effective) than usual - so BMP may be doing this. I think you need to regulate this yourself based on other factors - such as - are you getting a good sleep.
I believe that to obtain the performance we are looking for - we need to get a good sleep, have low stress and be able to assimilate nuitrients well (healthy gut and bowel) - which are all things that get trashed when I utilize too much caffeine. I don't use pre-workouts or stims anymore. Just 2-3 cups of coffee per day (4 cups and I personally cross that line).I think you are right. I'll start cutting back tomorrow and see if it helps.
Caffeine has its benefits. Just limit it to 200mg. I don’t see anything wrong with that amount.
What is your mega dose and do you feel it worked?
You will get rewarded for easing back....good job.Been needing an excuse to back off the caff anyways. Glad BMP is making me more sensitive to it. I had a Reign when I first woke up and that will be the only caff I have today. BMP > Caff.
This is speculation at this time. It is well known that nicotine usage causes bone weakening, through increased resorption and failed re-calcification. Since the BMP pathway controls this process, I'm speculating a central feedback mechanism where nicotine decreases BMP signalling, leading to bone resorption, thus strengthening (in a self-sabotage manner) the cravings for nicotine. It was just a personal observation that my own cravings for nicotine are vastly decreased.May have missed this but curious why it would increase sensitivity somehow. I thought @dsade and others mentioned that they didn't have as many nicotine cravings from a few pages back.
@Dsade I take a baby aspirin daily and also take Benazepril for high blood pressure. I take 1.5g daily of organic matcha powder in pills, and I've just come to see that green tea is also a p-gp inhibitor. However, I've also read that aspirin, even at low doses (study I saw was 100mg) is an activator of p-gp.This is speculation at this time. It is well known that nicotine usage causes bone weakening, through increased resorption and failed re-calcification. Since the BMP pathway controls this process, I'm speculating a central feedback mechanism where nicotine decreases BMP signalling, leading to bone resorption, thus strengthening (in a self-sabotage manner) the cravings for nicotine. It was just a personal observation that my own cravings for nicotine are vastly decreased.
THis is a little shaky for me to answer, as it comes very close to a line I can't cross legally, but let me look into that particular medication.@Dsade I take a baby aspirin daily and also take Benazepril for high blood pressure. I take 1.5g daily of organic matcha powder in pills, and I've just come to see that green tea is also a p-gp inhibitor. However, I've also read that aspirin, even at low doses (study I saw was 100mg) is an activator of p-gp.
Given that you've added p-gp inhibitors to the new formula to enhance update, do you have any recommendations on dosing times with BMP, aspirin, blood pressure meds?
I know you're not a doc, but I cant really ask my doc either as he's not much a believer in supplements, and I can guarantee he'd just tell me to stop taking whatever, etc.. he's very recently told me to not take creatine because of kidney damage lol.
I understand that, and I'm the one fully responsible for what I choose to take or not to take. I appreciate it.THis is a little shaky for me to answer, as it comes very close to a line I can't cross legally, but let me look into that particular medication.
Funny thing you guys mentioned caffeine. Again, I am in the middle of my 3rd bottle of BMP. I recently acquired a cold brew coffee maker. Cold brew requires about 7 oz of coffee beans for the same amount of coffee that 2 oz. of coffee beans makes with hot coffee and I did not think about the added caffeine. I have always been tolerant of stims and never have I ever considered caffeine to be a potential issue.
Well, last week I was finishing off my pot of cold brew in the afternoon and I started to just feel like h3ll. I just seemed to have an aversion to the coffee. The next morning the aversion remained and I decided to forgo all caffeine.
Something strange is happening though - life changing energy increases. I woke up at 4 AM yesterday naturally (something that would have been impossible for me up until then). I did go to sleep earlier than normal last night but was wide awake at 6 AM this morning and I have been having a tremendously productive week.
When I first started BMP I had an improvement in mood, then it leveled out. Now that I am off caffeine, I literally feel like a new person.
I hadn't considered BMP in this equation...I wonder now...
Either way, I have always been "stim tolerant" and could drop a gram of caffeine and go to sleep. Now, I do not think I will be using the stuff all that much ever again. I feel like a crazy, placebo driven zealot.
I understand that, and I'm the one fully responsible for what I choose to take or not to take. I appreciate it.
FWIW some mornings I take the Benazepril (note that I'm taking generic Benazepril HCL, not Lotensin, the "brand" version that also has a diuretic with it), along with the Matcha (an apparent p-gp inhibitor), and even Epitome, and have not had any negative incidents that are apparent to me. Its usually about 2, to 2.5, hours later that I will then take the baby aspirin (apparent p-gp activator).
I can always drop the aspirin during my BMP run, as that was a personal choice and not one recommended to me by my doctor.
Well I'll have to experiment and be careful, because I already know my docs "advice" lol.BMP contains Ligustrazine, which can act as a mild Calcium-Channel Blocker (at least in a few Chinese women when delivered intravenously.) That possibility may or may not possess the ability to augment the Lotensin, but I don't think the P-gp issues would be clinically signifigant based on what you described. Of course, as Matt stated, inquire of your doc if you aren't sure.
Granted, I'm only on 2 caps per day BMP but haven't noticed any changes in caffeine or nicotine tolerance/response.
Why are you only on 2 caps per day? 4 caps a day proved too hard on my body, so curious if you experienced similar effects. Thanks for your input.
Mu receptor agonists are associated with a host of undesirable effects. Inhibiting the release of gonadotropins being particularly notable. Curious how you wouldn’t even classify this as being a side effect?But one auxiliary effect I have noticed (wouldn't really call it a side-effect per say) is I've come to associate using BMP with delayed orgasm. I have concluded that it's likely the Sinomenine in the product, which acts as a MOP activator. Mu-agonists are notorious for delayed ejaculation/orgasm, so this product has possibly compromised my proficiency at "quickies."![]()
Sinomenine has a higher substrate affinity for the p-GP efflux pump. Co-administration with paeoniflorin shows a dramatic increase in p absorption, with a corresponding decrease in s absorption. Sinomenine "distracts" the p-GP efflux pump (and loosens caco-2 tight junction barrier) by acting as substrate, allowing the paeoniflorin to absorb.Mu receptor agonists are associated with a host of undesirable effects. Inhibiting the release of gonadotropins being particularly notable. Curious how you wouldn’t even classify this as being a side effect?
While that sounds promising, I then have to ask if we know the impact of paeoniflorin on human androgens? Not trying to be rude, just curious if you have any inside info that would contradict the ovary cell studies..Sinomenine has a higher substrate affinity for the p-GP efflux pump. Co-administration with paeoniflorin shows a dramatic increase in p absorption, with a corresponding decrease in s absorption. Sinomenine "distracts" the p-GP efflux pump (and loosens caco-2 tight junction barrier) by acting as substrate, allowing the paeoniflorin to absorb.
Likely very little of the Sinomenine is making it into circulation.
That was handled earlier in the thread.While that sounds promising, I then have to ask if we know the impact of paeoniflorin on human androgens? Not trying to be rude, just curious if you have any inside info that would contradict the ovary cell studies..
Yes, it seems that it wasThat was handled earlier in the thread.
Mu receptor agonists are associated with a host of undesirable effects. Inhibiting the release of gonadotropins being particularly notable. Curious how you wouldn’t even classify this as being a side effect?
Yes. Salidroside is also one of the main ingredients in Nerve Restore.On BMP for a little under 3 weeks now. Getting comments on slimming down, especially my face. I can tell in photos as well.
Bought a second bottle and adding Stanoplex tonight with it.
Wasn't there some talk about this reactivating things, nerves maybe, etc? I feel like I'm noticing some things..
Crap, sorry forgot to get back with you. I'll hit you up shortly.Should be starting this up soon, will post a log once I do.
I noticed this week that, out of the blue, my pants are feeling super loose, and my belt is loose even a notch tighter. This is strange because over the last 3 months I lost about 14 pounds and over the past 2 weeks I have gained 3 pounds back (life going on, diet not as solid).
I have been doing things that I would think make it worse and my body is actually feeling a bit leaner.
The only other change I have made is to cut out caffeine a few weeks back and I had a couple B12 shots. I doubt that is doing it...but who knows.
Yes sir, has helped my sciatic nerve as well as Thoracadorsal nerve, overall inflammation is down as well =)On BMP for a little under 3 weeks now. Getting comments on slimming down, especially my face. I can tell in photos as well.
Bought a second bottle and adding Stanoplex tonight with it.
Wasn't there some talk about this reactivating things, nerves maybe, etc? I feel like I'm noticing some things..