Must Read This ! "The One" is just DHT

It could have been developed to be injected (the blood has a pH of 7.4) where as the stomach has a pH of 1-3. Also could be used as an eye-drop, intranasal, ear drop, who knows. The compound was patented so the pharmaceutical industry had found some use for it.. just the question is what.

actually given the way that patent was written, it was just patented IN CASE the pharma industry found a use :)
 
There was actually one thread where a rep from IFORCE was recruiting board members to test their designer steroids on, and was asking the testers to pay for their own bloodwork. If you have a company and you plan on making money off of this product, you should be willing to pay for all R&D cost, and that is including bloodwork of the testers. I have never seen that in any other industry where the tester has to pay for the testing. A little ridiculous if you ask me.

Yeah, that proves my theory that I had about iForce. :rolleyes:
 
So heres a fun example. This molecule

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and this molecule
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Cleave off 2 methyl groups and the hydroxy. Similar structures, but the first is methamphetamine, the second ephedrine... So sure, chemically they are close but WAY different effect. I'm sure someone can come up with 2 that are even closer structurally but significantly different effect wise.

LOL- good one- small change in any structure can lead to numerous different changes in the effects of said molecule- even minor A ring alterations in these compounds can lead to significantly different effects. Other potential variables include:
stereochemistry
isomers
5-AR vs. non 5-AR
A ring saturation
methylation
bonding
synthesis methods (big one)
etc.

list of variables as differentiators on these compounds is extremely voluminous- I really wish people would do their homework instead of just trying to stir up **** and act like a baby

some suggested reading:
start with the write up for The One- read all the referenced studies given
pharmacology
basic chemistry concerning these compounds
synthesis methods

then come back and start another thread about what you have learned.....you may have a more solid argument, or, in this case, realize that you shouldn't have started this thread in the first place......
 
Im not so sure how good the One really is. Please send me ten bottles so I can do futhur testing.

PS. Dont forget the 2nd gear.
 
This doesn't make any sense. If the oxime group is cleaved off in the stomach, there will be no intrinsic activity nor any "time release" of the MDHT. If the acidity of the stomach (this happens in other drugs) can cleave off that group then you are left with straight MDHT. Then the author is right, this is a pro-drug to MDHT and the conversion is occuring in the stomach rather then the liver.

But at the same time we have to go back and question the legitimacy of the original article that is claiming this. Can someone back through the research and find out anything on steroidal oxime groups being cleaved off in the stomach?

little of the oxime, if any, is hydrolyzed in the stomach....
 
Uh you still do damage control regardless if the claims are bogus or not buddy... How many people are asking for an explanation already on this one....? My point exactly.

Lol 4?

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Necessary??? Is it necessary for me to drink my own urine?
No, but I do it anyway because it's sterile and I like the taste.

O/T but a large proportion of ingested Anavar remains in the urine unchanged- I guess you could call it recycling :)
 
O/T but a large proportion of ingested Anavar remains in the urine unchanged- I guess you could call it recycling :)

What i hadn't known until recently is that anavar is the only steroid that doesn't close growth plates.... but i still wouldnt get it from pee. Although i do have a standing offer from a pregnancy forum that my wife still visits to donate pee for me to make my own HCG :D
 
The Lord wants us to be with a woman. Just not psycho bitches. It's in the Bible, in so many words.

Did you get my response on the 2nd Gear lable?

The truth in one of the best ways I have seen it said lol.

Yeah I just seen the response, thanks. It makes sense as well. I was just interested in the reasoning on that since its something I plan to injest lol. It looked like a bit of overkill, then again you brought up some perfect points. I am content :D
 
"So in your limited research you can determine the long term health effects of a chemical that has zero study in that regard. You can determine the carcinogenic risk, the proliferation of dormant tumors cells in organs like your liver, kidneys, spleen, colon etc.

Think for a minute how many FDA approved drugs that have had years of studies before release have been removed from the market because of adverse health effects. They invested millions of dollars in research and trials before they released it with FDA approval to only find out that it was actually dangerous.

Consider that supplement companies, most in particular, DS manufacturers, invest zero to this research. The little research they do in labs might be limited to lipid and liver profiles on 3 people and the bulk of their trials are done on test subjects who report anecdotal findings of increased strength and bodyweight.

I hate to break it to you but you or I cannot possibly know what you are doing to your body taking these things and the manufacturers know equal or less. Your confidence level in your educated consumer roles is of little value when you consider that 10 or 20 years from now your mortality may be in the balance.

Just some food for thought."









Buzzzzkill!!

You just blew my plans to debut a deep-fried, methyl-hydrogenated designer anabolic.
 
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Buzzzzkill!!

You just blew my plans to debut a deep-fried, methyl-hydrogenated designer anabolic.
I think Krispy Kreme has already cornered that market. Word on the boards is that it will stack great with The One. The user logs are showing guys gaining like 15lb in two weeks.
 

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What i hadn't known until recently is that anavar is the only steroid that doesn't close growth plates.... but i still wouldnt get it from pee. Although i do have a standing offer from a pregnancy forum that my wife still visits to donate pee for me to make my own HCG :D

LOL-they have found in recent studies that estrogen is the culprit for epiphyseal closure, not testosterone- they gave short stature children AIs, and some of them ended up growing 6cm taller than expected height :)
 
Wow. This is one of the worst case of "cyber bullying" and "bullying and attacking whoever disagrees with you" that I have come across in AM.

Oh, well. I have learnt a lot from AM, and I think I will continue to do so. But this series of posts definitely gave me a bad impression.

Seems like everyone is dumping on the OP, and jumping in to stomp on him when he is down, and questioning his motives and such. (e.g. why is he trying to discredit the product? what were his past cycles and experiences? etc)

Of course, we could do the same thing to the people trying to defend the product. What are their motives and incentives. ( This group of people obviously have a vested interest in defending their product, and making sure that it sells, especially the people who invested lots of $$$ in it. Others may be 'linked' or 'related' to the company, or are trying to brown nose the company so that they can be testers in the future. Why the hell are they attacking the OP's previous history?????)

I actually felt that the OP definitely brought up something very interesting for all of us. That the compounds involved are not that original (as originally claimed), but modified from something else.

Nevertheless, I have seen enough BS and PR from supp companies than to expect otherwise.

As to the claims that the product works because of the various unsponsored logs, well, I am not sure how much to 'trust' these logs.

Anyway, the sample size so far (10 ppl ~20 ppl ??) is too small for me to be confident about the results.

Anyway, good luck to all who bought the product. Hope you really get the gains and minimal sides as claimed. Hope your PCT goes well, and you keep your gains and your health.

Good luck to AM too.
 
That the compounds involved are not that original (as originally claimed), but modified from something else.

We state that pretty clearly ourselves. Its an all new compound as its never before been available for sale, and we stated that it was originally mentioned . There hasn't been any new prohormone/designer steroids since the 1960s by your definition as Vida mapped out all the possible ones since the molecules can only bond in certain ways.

A clip of the post launching the product, from back in january

Brief History:

• Primary active ingredient (17a-methyl-etioallocholan-17b-ol-3-hydroxyimine) was first described by Z. Cekan and B. Pelc, Effects of 1-alkyl substitution on the biological action in a series of androstanes. Steroids 8,209 (1966).
• Never commercially produced – A COMPLETELY NOVEL MOLECULE.

We stated that more than 2 months ago.... Heres the thread

http://anabolicminds.com/forum/company-promotions/113105-here-ans-write.html

So again, other than being inflammatory i'm not sure what was brought to the table. The only factual piece of data was that there was actually a 1963 patent that described the product as well, so we were incorrect by 3 years on when it was first described. Not sure how relevant that is to anyone.

I do agree that bullying is not positive for AM or any public forum, but like I said myself repeatedly "where is there something factual in that article that you want me to address". The naming using the etioallocholan? using the Vida specified A:A ratios that are from in vitro animal tissue rather than oral human dosing? Those are industry standard, which i'm sure the author (and all the rest of us) has seen enough times that i'm not sure why he mentioned it. The OP refused to give anything factual that he wanted addressed from the article, yet tried to come up with other bizarre reasons as to why The ONE is a flawed product, most of which made no sense from a scientific viewpoint. Trying to show how adding a methyl group to a hormone affects it by posting an article about how the body uses methyl groups from SAMe in the liver? Just bizarre behavior the whole way around which is why his motives were questioned.
 
I’m not one to post much but the issue I have with this whole dam thread is that is seems to based on a website that really has no proof of credibility. They don’t even describe who they are anywhere on the site. Therefore, what gives them the right to say anything regarding this product? For all we know its some unqualified yahoo making claims that he/she has no right to make. I don’t know about you but I’m real skeptical about someone who makes claims without any qualifications. Just my two cents.
 
Wow. This is one of the worst case of "cyber bullying" and "bullying and attacking whoever disagrees with you" that I have come across in AM.

Oh, well. I have learnt a lot from AM, and I think I will continue to do so. But this series of posts definitely gave me a bad impression.

Seems like everyone is dumping on the OP, and jumping in to stomp on him when he is down, and questioning his motives and such. (e.g. why is he trying to discredit the product? what were his past cycles and experiences? etc)

I think the frustration with the OP is that they addressed it very well, and it was like talking to a sign. And also it was one of these "look what I read on the internet it must be completely true!" If there was some more legit argument there, responses would have been different I think.

I think they elaborated enough very early on. I do think the frustration should be redirected at the source, which seems to be a very incompetent source of insight about chemical compunds, other than ranting about its similarities and its origins...which they translate similarities as "the exact same thing". Via the eye catching headline.
 
whats the point of trying to argue.

anyways, my wife says the same thing to me, about side effects, but then tells me how hot I look. So in conclusion, I've bought the one, and will be taking it for 4 weeks, then after that taking epistane+tren for another four weeks. I'll look good for the summer, but have cancer at 40. dead by 50. or be hit by a drunk driver and die tomarrow night. life is a gamble either way.
sucks.:rippedhand:
 
It's always the path that matters most. It could start as one thing and end up "just mDHT," other than safety throughout the process, only the intermediates matter.
You have $0>> you worked your whole life>> you make $1M
You have $0>> you stole from people who trusted you>> you make $1M

You take "TO">> intermediates help you gain 15lbs>> mDHT
You take Product X>> intermediates help you gain 6lbs but you lose some hair>> mDHT
Both are "just mDHT" in the end but overall the two are very different.
 
Wow. This is one of the worst case of "cyber bullying" and "bullying and attacking whoever disagrees with you" that I have come across in AM.

Oh, well. I have learnt a lot from AM, and I think I will continue to do so. But this series of posts definitely gave me a bad impression.

Seems like everyone is dumping on the OP, and jumping in to stomp on him when he is down, and questioning his motives and such. (e.g. why is he trying to discredit the product? what were his past cycles and experiences? etc)

Of course, we could do the same thing to the people trying to defend the product. What are their motives and incentives. ( This group of people obviously have a vested interest in defending their product, and making sure that it sells, especially the people who invested lots of $$$ in it. Others may be 'linked' or 'related' to the company, or are trying to brown nose the company so that they can be testers in the future. Why the hell are they attacking the OP's previous history?????)

I actually felt that the OP definitely brought up something very interesting for all of us. That the compounds involved are not that original (as originally claimed), but modified from something else.

Nevertheless, I have seen enough BS and PR from supp companies than to expect otherwise.

As to the claims that the product works because of the various unsponsored logs, well, I am not sure how much to 'trust' these logs.

Anyway, the sample size so far (10 ppl ~20 ppl ??) is too small for me to be confident about the results.

Anyway, good luck to all who bought the product. Hope you really get the gains and minimal sides as claimed. Hope your PCT goes well, and you keep your gains and your health.

Good luck to AM too.

In a nutshell, I understand your viewpoints and having healthy skepticism about supplements and supplement companies is a good thing. However, as it pertains to the ONE...in order to make a judgment call I would advise you to do as I commonly say "Nut up, or Shut the F*ck up!"

Be advised...there is no disrespect intended. I appreciate you being blunt and not sugar coating anything and in return...I am no different.

I am not going to make any claims and tell you what to believe, or try to convince you either way...you are your own person and you have your right to your own opinions.

Cheers!:cheers:
 
I think the frustration with the OP is that they addressed it very well, and it was like talking to a sign. And also it was one of these "look what I read on the internet it must be completely true!" If there was some more legit argument there, responses would have been different I think.

I think they elaborated enough very early on. I do think the frustration should be redirected at the source, which seems to be a very incompetent source of insight about chemical compunds, other than ranting about its similarities and its origins...which they translate similarities as "the exact same thing". Via the eye catching headline.

In a nutshell....:goodpost:. I think your theory would be correct that responses would have different if the matter would have been handled differently.

Cheers!:cheers:
 
Healthy skepticism is fine...I always believe the proof's in the pudding. If the stuff works, and it does, that will all shake out long term. Some of our biggest proponents started out as skeptics.

I think this issue has been as beaten up as it can possibly be.
 
I might be mistaken, but i believe the closest non-methylated cousin to this is already in use as a prescription steroid for eye drops after lasik/PRK surgery.
 
whats the point of trying to argue.

anyways, my wife says the same thing to me, about side effects, but then tells me how hot I look. So in conclusion, I've bought the one, and will be taking it for 4 weeks, then after that taking epistane+tren for another four weeks. I'll look good for the summer, but have cancer at 40. dead by 50. or be hit by a drunk driver and die tomarrow night. life is a gamble either way.
sucks.:rippedhand:
As cool as you want to think you are LIFE is NOT a GAMBLE. It is a matter of intelligent decisions and choices that should not be left to chance. Leave a good life insurance policy for your wife. She's gonna need it for the next HOT guys she finds.
 
As cool as you want to think you are LIFE is NOT a GAMBLE. It is a matter of intelligent decisions and choices that should not be left to chance. Leave a good life insurance policy for your wife. She's gonna need it for the next HOT guys she finds.

lol, exactly what I was thinking!

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Something happens along the process of aging. You get to a point where you stop worrying about getting old and you worry you won't live to be old. It changes a man. Maturity!!! You can't buy it.
 
As cool as you want to think you are LIFE is NOT a GAMBLE. It is a matter of intelligent decisions and choices that should not be left to chance. Leave a good life insurance policy for your wife. She's gonna need it for the next HOT guys she finds.


yea, I've got a good life insurance pollicy set up. and life isn't a gamble? tell that to the family who is driving to dinner and a drunk driver speeds through a red light broad sides their mini van, and kills their children in the back. or to the family who's child is killed by a stray bullet from gang violence?
life is full of choices, one could argue, hey, those people from 9/11 chose to get on that plane that day, wrong place, wrong time. or one could say it wasn't their choice to get on a plane with an extrmely religious muslim who had plans to kill everyone on that plane including himself and the people in the world trade center. so are you saying all those people had a choice whether or not they were going to die that day? that it's their fault for getting up, going to work? really, I dont understand what your sayig, help me please.

life is full of choices, this is true, but life is also a gamble. yesterday is gone, tomarrow may never come, live for today. maturity does not come with age. I know im not, and never claim to be mature. im sorry, but if you think life is not a gamble, I think you are wrong, it is and you only have so much control over things that happen to you.

yes I take anabolics that may or may not cause problems in the future, people eat foods and drink stuff everyday that may or may not cause cancer.

yes, life is a gamble, and even when gambling you make a choice. love it or hate it.
 
You guys are gettin' way too deep with this s***. Now, paying $70 for a 1966 DHT constituent/clone/precursor, whatever... now THAT'S a f**k*n gamble. :bandit:
 
Look back to some of the reviews on mdht, and you'll read that most users reported drastic strength gains, agression (can be good or bad), hardness. Not too much in teh mass dept which fueld my skepticism toward the claim to put on 10-15lbs of pure muscle.


And the people who bought the one and running their own logs are probably making their log look "good" so they get sponsored with your next product. I just am finding it hard to believe anyone putting on 15-20 pounds in a couple weeks off this product that you guys claim. Just by reading the logs that arent on this board confirms my thoughts.

I know this is a quote from way back in the thread, but I don't feel like going through to whole thread to find a better post to respond to; I know a guy who could never gain any weight and then he took The One and put on 20lbs of lean muscle over the full cycle. Now whether it was due to increased appetite or agression or whatever I have no clue; all I know is it's true. Also, it is yet to be seen if he will be able to maintain the mass as he is just now starting the second gear. We shall see. I am about to try it out myself because I was so impressed with his results; maybe they were just placebo :dunno:

Edit: Hell, maybe the size gains are due to the consumer working out and eating right because they have $70 invested in The One and they don't want to waste it, lol who knows. It doesn't matter as long as it works, am I right? I'm sure it's a quality product and I hope I see the same results as most see.
 
I know this is a quote from way back in the thread, but I don't feel like going through to whole thread to find a better post to respond to; I know a guy who could never gain any weight and then he took The One and put on 20lbs of lean muscle over the full cycle. Now whether it was due to increased appetite or agression or whatever I have no clue; all I know is it's true. Also, it is yet to be seen if he will be able to maintain the mass as he is just now starting the second gear. We shall see. I am about to try it out myself because I was so impressed with his results; maybe they were just placebo :dunno:

Edit: Hell, maybe the size gains are due to the consumer working out and eating right because they have $70 invested in The One and they don't want to waste it, lol who knows. It doesn't matter as long as it works, am I right? I'm sure it's a quality product and I hope I see the same results as most see.

Losing some gains is normal, but if his nutrition and training continues to be right during his PCT then there is no reason why he cannot maintain his gains and even add to them.

IMO, regardless of whether you are using hormonals or anything else you should STILL be eating and training right for your goals, since you are investing time and effort and energy and money (i.e. gym membership, supplements, etc.) into doing so. You should always be pushing yourself in training and keep progressing; else what is the point in doing it?


~Rosie
Team APPNUT
 
Losing some gains is normal, but if his nutrition and training continues to be right during his PCT then there is no reason why he cannot maintain his gains and even add to them.

IMO, regardless of whether you are using hormonals or anything else you should STILL be eating and training right for your goals, since you are investing time and effort and energy and money (i.e. gym membership, supplements, etc.) into doing so. You should always be pushing yourself in training and keep progressing; else what is the point in doing it?


~Rosie
Team APPNUT

Oh I agree I was just being sarcastic (sorry if I came across the wrong way). My point was just that in spite of some of the ATTEMPTED negative jabs at The One and the fact that a few people doubt it's abilities, it does work and that's all that matters.

This is going to be my first run with a prohormone. I have been doing alot of research and I decided to go with The One due to it's reported low occurence of side effects and it's effectiveness which I've seen first hand. I am looking forward to it and will definately share my results.
 
Oh I agree I was just being sarcastic (sorry if I came across the wrong way). My point was just that in spite of some of the ATTEMPTED negative jabs at The One and the fact that a few people doubt it's abilities, it does work and that's all that matters.

This is going to be my first run with a prohormone. I have been doing alot of research and I decided to go with The One due to it's reported low occurence of side effects and it's effectiveness which I've seen first hand. I am looking forward to it and will definately share my results.

I see.

If you decided to log it, please post your log link here: Invalid Link Removed

If not, please post any feedback here: http://anabolicminds.com/forum/applied-nutriceuticals/119562-feedback-one.html

Cheers :cheers:


~Rosie
Team APPNUT
 
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