I know that the old skoolers mostly did the 1 dose a day, but I think that was just so they didn't have to count and remember
![Big grin :D :D](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
particularly with stuff that has shorter half life, having to dose 4-5 times over the day to stay at constant levels is a drag.
For me its always been 2 points that make either pulsing, or doing full dose all at once make more sense.
The first is suppression. With short to moderate half life substances, having it all be clear of system before you go to sleep means you are more likely to create more testosterone while you sleep. Also related to this is the math of suppression. Using compound x, lets say that at 20mg your body sees enough androgen in blood to no longer produce test. taking that 20mg 3x a day means your body has that "enough androgens" all day long. Taking 60mg at once means your body has the "enough androgens" signal for only 6-8 hours, so the other 16-18 hours of the day it still sees the need to produce.
The other point is sleeping. With some things like 1-t having 3-4 hour half life, am I supposed to wake up during the nite to take it ? If not, i'm not keeping the constant levels anyhow, so trying to force constant levels during the day to have it disappear at night seems pointless.