Prolactin Control: Inihibit-P or Prolactrone?

JYD

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Like the title says, looking to control prolactin. Stress is at an all time high. Need to control prolactin... I have something for cortisol.

Cheers!
 
mw1

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Like the title says, looking to control prolactin. Stress is at an all time high. Need to control prolactin... I have something for cortisol.

Cheers!
Check out the reply from MrCooper on the subject...Inhibit P all the way
 
jgntyce

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X2 with inhibit P.
 
Jiigzz

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Inhibit P has stellar feedback across the board. You can't go wrong
 
LeanEngineer

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Another vote for inhibit P. I've seen tons of positive reviews on it and I love it myself. I'd go with it especially if you've never tried it.
 
booneman77

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I've used both personally and never saw a difference in effects so for me, its a no-brainer since inhibit-p is waaayyyyyy cheaper
 
kbayne

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Like the title says, looking to control prolactin. Stress is at an all time high. Need to control prolactin... I have something for cortisol.

Cheers!
Inhibit-P or Mucuna Pruriens extract L-Dopa 98%
 
AntM1564

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I haven't used either, but I am an advocate of SNS. Inhibit P gets my vote.
 
warbird01

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I've used both personally and never saw a difference in effects so for me, its a no-brainer since inhibit-p is waaayyyyyy cheaper
$25 v. $45
 

JYD

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I stacked the Inhibit-P with VPI Arimistane and am having trouble sleeping. Think I'm gonna drop the arimistane.
 
The_Old_Guy

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Do you have fluid coming out of your nipples, or a blood test showing high prolactin?
 

JYD

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It was high about a year ago. I did a run of inhibit-p. I chose to take it for the l-dopa effects.
 
cheftepesh1

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Definitely inhibit-p for the price and quality alone makes it the better choice.
 
The_Old_Guy

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It was high about a year ago. I did a run of inhibit-p. I chose to take it for the l-dopa effects.
So you had it measured via a blood test, 1 year ago?
 

JYD

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So you had it measured via a blood test, 1 year ago?
Hey old man, leave it alone. We get your point, okay? You clearly have nothing else better to do this morning. Life's short, especially when you're old. I took a productive i have taken before for the mood and well-being effects I had on it and I'm taking it again.

Give it a rest. Go take a nap.
 
The_Old_Guy

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Hey old man, leave it alone. We get your point, okay? You clearly have nothing else better to do this morning. Life's short, especially when you're old. I took a productive i have taken before for the mood and well-being effects I had on it and I'm taking it again.

Give it a rest. Go take a nap.
Hahaha! Wow, I feel so put in my place. You clearly have zero knowledge about any of this stuff - enjoy your placebo and ever shrinking wallet.
 
The_Old_Guy

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Since I always like to educate, consider that 20ng/ml is considered the top of normal range for prl in men. Only about one half of 1 percent (in a study on 1,821 men) have prl above 20ng/ml. In another study, levels below 5ng/ml were shown to:

https://www.ncbi.nlm.nih.gov/pubmed/19210705

The reason that low prolactin can so negatively affect your sex life was shown in a 2009 study in the Journal of Sexual Medicine that divided over 2,500 men with sexual dysfunction into quartiles and found that the low prolactin men were:

74% more likely to have Metabolic Syndrome
43% more likely to erectile dysfunction resulting from arterial disease and plaque
38% more likely to have premature ejaculation

The lowest quartile consisted of prolactin levels below 5 ng/ml. For this reason, if you having any kind of erectile dysfunction or loss of libido and, if you also have low prolactin levels, this may provide you a clue as to how to troubleshoot the underlying issue.
If you don't know where you are, what happens if you take a "Prolactin Lowering Supplement" and it puts you below 5ng/ml?

If you are trying to influence something that has a "healthy range", where above or below is BAD, I think it would behoove people to know what their number is.

For other stuff that doesn't matter, go ahead and recommend/take stuff til the cows come home - there's no LD50 for Ashwaghanda or Maca, etc... - but stuff that influences hormones? Irresponsible to recommend or take without knowing IMO.
 
vujade

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The_Old_Guy a loan wolf in the bodybuilding world on a crusade to educate the masses of the evils of supplements one post at a time
 

JYD

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Since I always like to educate, consider that 20ng/ml is considered the top of normal range for prl in men. Only about one half of 1 percent (in a study on 1,821 men) have prl above 20ng/ml. In another study, levels below 5ng/ml were shown to:

https://www.ncbi.nlm.nih.gov/pubmed/19210705



If you don't know where you are, what happens if you take a "Prolactin Lowering Supplement" and it puts you below 5ng/ml?

If you are trying to influence something that has a "healthy range", where above or below is BAD, I think it would behoove people to know what their number is.

For other stuff that doesn't matter, go ahead and recommend/take stuff til the cows come home - there's no LD50 for Ashwaghanda or Maca, etc... - but stuff that influences hormones? Irresponsible to recommend or take without knowing IMO.
Hey, thank you for this. I thought about it before you sent this and said, "This guy prolly gets annoyed with people buying sh&t and not doing proper research." And that's legit; I get the same way when my buddy spends a bunch of cash on music gear he doesn't need or know anything about. I was coming from the standpoint that if I want to part with $20 on something that I felt/placebo made a difference, I should be allowed to do that and not be judged.

I'll apologize for getting a bit annoyed, but I knew where you were going and didn't care to here it: it's my $20 and I don't regret losing it.

That said, I do appreciate you looking out for others and their wallets: that is EXACTLY why I come here. I am one of those that will occasionally try something without bloodwork, but the only things I do are minimal, like LJ100 and a cortisol product as I do have a very stressful life at the moment.

Either way, thanks for the follow up and for your help. Cheers.
 

BlockBuilder

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I took inhibit p without knowing my prolactin levels but I do take an antidepressant (lexapro). Loved it. Sex drive went through the roof and my loads were bigger than they've ever been in my life. Placebo or not don't care.
 
GQdaLEGEND

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love inhibit P
p5p, vitex, l-dopa .. all you need and can find close to $20
 
The_Old_Guy

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I see the emoji! :D

Hell, Carbergoline has so many negative side effects, I sure as shjt would try an OTC first too - if I *knew* I was high ;)
 
Jiigzz

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thebigt

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jgntyce

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yup, it always works for me....inhibit-P and E are both effective and cheap compared to others products in their category's!!!
Hence why SNS sells quality products and cost effective prices!
 

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Has anyone used Inhibit-P during a cycle with deca and test?
 

ucheoma

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LOL at the wave of recommendations. Note that none asked the difficult but truthful question posed by oldguy.

OP, of course its your money and body but no need to get ageist just because someone's trying to educate you. Good on you for apologising
 

JYD

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LOL at the wave of recommendations. Note that none asked the difficult but truthful question posed by oldguy.

OP, of course its your money and body but no need to get ageist just because someone's trying to educate you. Good on you for apologising
Ha! Agreed, but I wasn't being ageist at all. Rather, I was going off his name. 49, is not old in my book. 65+ and you're on your way. But judging by Old_man's pic, he could probably tell me to drink my own urine to look that good and I'd try that.
 
Jiigzz

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LOL at the wave of recommendations. Note that none asked the difficult but truthful question posed by oldguy.

OP, of course its your money and body but no need to get ageist just because someone's trying to educate you. Good on you for apologising
Yeeeah, but he posted from the side of commin issues, but didn't note that decreased PRL even in normal populations still increased sexual issues as well.

it has the data to support it from the side of that as well.
 

ucheoma

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Yeeeah, but he posted from the side of commin issues, but didn't note that decreased PRL even in normal populations still increased sexual issues as well.

it has the data to support it from the side of that as well.
Not sure i fully get your drift. However all he mentioned was stress was at an all time high. No further info on this and in comes a wave of company recommendations. Not one post suggesting tackling the root cause of verifging how he knows his prolactin is high. I know this is a supp thread but cmon!
 
The_Old_Guy

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If you look at the conflicting studies posted, my two totaled about 4,500 Men.... the other one was 10(?) Gun to my head, I know which side I would choose based of the N= numbers alone.

And, so... are we promoting/advocating that we should strive for 0ng/ml?
 
Jiigzz

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If you look at the conflicting studies posted, my two totaled about 4,500 Men.... the other one was 10(?) Gun to my head, I know which side I would choose based of the N= numbers alone.

And, so... are we promoting/advocating that we should strive for 0ng/ml?
But yet you seems to have misunderstood/ misinterpreted what the study was testing for, because you indicate that low prolactin is responsible for increasing the rates of many lifestyle diseases (as indicated by your first post ITT); yet the authors state that low PRL is likely resultant from blunted central serotonin transmission, which is also investigated here: https://www.ncbi.nlm.nih.gov/pubmed/10459408 and here: http://www.sciencedirect.com/science/article/pii/0024320578905738

As a quote from inside the paper you referenced:
The association between BCSF and MetS is not surprising, as central serotonin is involved in the control of many behaviors (eating, locomotion, sleep) and autonomic functions (thermogenesis, cardiovascular control, insulin secretion) possibly related to the development of the syndrome
[24,25]. However, at present, it is not clear whether the impairment of central serotonergic pathways should be considered as a possible cause
of MetS or of another abnormality induced by MetS itself or by insulin resistance.

In animal models, diabetes per se can disturb central serotonin synthesis and decrease serotonin receptor affinity [30]. Furthermore, pituitary gland, and in particular lactotroph cells, undergo increased apoptosis in poorly controlled diabetes mellitus [31].
And further:

Our findings are consistent with the hypothesis of a hyperglycemia-induced reduction of PRL secretion.
And again:

Our data do not support the hypothesis of a metabolic derangement induced by low PRL
So in actual fact, the data you posted supports the idea that disturbed serotonin transmission underpins a lot of the issues you relate to PRL, when in actual fact salivary PRL is a marker tool used to identify serotonin transmission.

Yes, the abstract states one thing, but if you actually read the paper, you will find more to the story.

The present data show, quite unexpectedly, that low, rather than high, PRL levels are associated with arteriogenic ED. In fact, the detrimental effect of hyperprolactinemia on male sexual behavior is mainly mediated by a
decreased sexual drive and by the concomitant hypogonadism [5]. Mechanisms through which PRL controls penile vascular reactivity are beyond the aims of the present study. However, we can speculate that the association of MetS and arterio-genic ED with low PRL reflects the impairment of central serotoninergic transmission.
Then of course we can go back and see that impaired serotonin transmission can be attributed to that a lot of pathologies:

Role in insulin release: http://journals.plos.org/plosbiology/article?****10.1371/journal.pbio.1000229

Serotonin derivatives and atherogenesis: http://pubs.acs.org/doi/abs/10.1021/jf060254p

etc.
 
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warbird01

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I see the emoji! :D

Hell, Carbergoline has so many negative side effects, I sure as shjt would try an OTC first too - if I *knew* I was high ;)
**** I remember the first time I took caber. Accidentally took it during the day and passed out lol
 
Jiigzz

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GQdaLEGEND

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and you can find it under $20 at many sites

Heck of a deal .. just googled "but SnS inhibitP" found it in 2stores and in stock
 
thebigt

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and you can find it under $20 at many sites
if I am ordering mainly sns/cel products I've found that nutraplanet prices are usually the lowest!!!
 

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