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EvoMuse BMP - Body Modify:Phenotype Writeup

just placed an order for the BMP double pack, plus Virile Mane! Stoked! The BMP from our TPS orders will be heading out soon too correct? Hope you're doing better Matt!
 
cubs1987 said:
just placed an order for the BMP double pack, plus Virile Mane! Stoked! The BMP from our TPS orders will be heading out soon too correct? Hope you're doing better Matt!
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Thanks!

Yes, all of the TPS order are in one stack, and the BMP-only orders are being separated.
 
Just got a couple nerve restore/myo elite stacks to try. Definitely getting two of these Friday if they are still around :)
 
GiftedNatty said:
Just got a couple nerve restore/myo elite stacks to try. Definitely getting two of these Friday if they are still around :)
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Nerve restore is so dam good with epi-(-) very good choice. find its made me allot more explosive and face paced to you become allot quicker with your reps and can really controll heaiver sets better. alongside epi-(-)'s endurance it makes for a wicked strength+endurance combo pre great as a non stim option to with high volume
 
Auslifter said:
Nerve restore is so dam good with epi-(-) very good choice. find its made me allot more explosive and face paced to you become allot quicker with your reps and can really controll heaiver sets better. alongside epi-(-)'s endurance it makes for a wicked strength+endurance combo pre great as a non stim option to with high volume
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I haven't actually tried epi just yet at all. I love HV and E9 though and currently use both. I'm hoping nerve restore will help some of my back issues(nothing serious just some dull pain here and there mostly in my upper back & shoulder/trap area)
 
Eclectic9kid said:
That's exactly why I figured I'd try it.. And it has totally helped.
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That's a relief to hear. It's never joint issues in my case so I thought this would be perfect for me. I foam roll weekly and my upper back tension is still unreal lol
 
Man I just found this thread and am very intrigued. I love dsades innovative touches and have been using your stuff for years. Time to look into this.
 
This was on fb last night for those who don't follow us ;)

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Well I screwed up my fulfilling everyone's entire TPS order. Having to type each address in again by hand. My apologies if is screw up any names...typing like a madman.
 
And he accidentally locked the thread and it's now open. :lol:
 
What a dumbas....oh wait
 
Showing as in stock or out of stock?
 
I still have BMP in stock and MyoElite will be back in stock next week!
 
Alright cool. Is BMP one of thse things that get better with time? I have two bottles already and another will stretch about 6 weeks into a cut I have planned
 
mechka_grizli said:
Alright cool. Is BMP one of thse things that get better with time? I have two bottles already and another will stretch about 6 weeks into a cut I have planned
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yeah absolutely.
 
How should you take both doses if you workout in the morning?? Directions say 1 an hr before you workout and 1 in the morning.
 
dsade im sorry but I did search around cause I remember you saying it, just can't locate it.

But what is the reason for the synergy between BMP and MyoE and what difference in effects will be noticed?
 
Doesn't look like it's been mentioned, so I was wondering if vitamin k was not recommended to go along with BMP? From the info I've found it looks like one of the proteins it interacts with (MGP) has a modulatory role with BMP-2, at least in terms of arterial calcification where it helps prevent it by inhibiting BMP-2. I also couldn't find if it mattered if it was carboxylated or not.
 
SonicSWOLE said:
I see BMP and MyoE are up at NP and *****************, fire that mean orders from your store for BMP shipped?
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They should all be out the door. If you have an order you need me to check, shoot me a PM
 
If working out in the morning (fasted), should BMP be dosed pre-workout and then 5-6 hours later? Also, is there an advantage to dosing 1 more extra cap, and if so, when would it be most beneficial? Just wondering because I've got 4 bottles sitting and I'm starting this tomorrow.
 
ma70 said:
If working out in the morning (fasted), should BMP be dosed pre-workout and then 5-6 hours later? Also, is there an advantage to dosing 1 more extra cap, and if so, when would it be most beneficial? Just wondering because I've got 4 bottles sitting and I'm starting this tomorrow.
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Yes, dose preworkout then later.

With BMP I don't think there will be an advantage in dosing more.
 
dsade said:
Yes, dose preworkout then later.

With BMP I don't think there will be an advantage in dosing more.
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Alright. Thanks! I'll be starting BMP and my second bottle of Hybrid BRITE. Currently running out of MyoSynergy so I might hop onto MSE soon, but I think I want to analyze the effects of BMP before I jump onto that.
 
how would you suggest dosing for the night lifters (5:30pm-7:30pm). Dose with breakfast in the morning and then pre-workout?
 
cubs1987 said:
how would you suggest dosing for the night lifters (5:30pm-7:30pm). Dose with breakfast in the morning and then pre-workout?
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That's how I'm doing it, when I can workout.
 
BlackWinging said:
Doesn't look like it's been mentioned, so I was wondering if vitamin k was not recommended to go along with BMP? From the info I've found it looks like one of the proteins it interacts with (MGP) has a modulatory role with BMP-2, at least in terms of arterial calcification where it helps prevent it by inhibiting BMP-2. I also couldn't find if it mattered if it was carboxylated or not.
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Bump on this.
 
BlackWinging said:
Doesn't look like it's been mentioned, so I was wondering if vitamin k was not recommended to go along with BMP? From the info I've found it looks like one of the proteins it interacts with (MGP) has a modulatory role with BMP-2, at least in terms of arterial calcification where it helps prevent it by inhibiting BMP-2. I also couldn't find if it mattered if it was carboxylated or not.
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Sorry I missed this...It looks like keeping your vitamin K intake at a reasonable recommended level will prevent calcification in the VSMCs and act as a protective agent. but it/s dependent upon the MK4 form.

I would say that overall a normal intake of Vitamin K (the below indicates dairy and meat as sources) will be protective without inhibiting BMP-2's contribution to muscle growth.

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Thromb Res. 2008;122(3):411-7. doi: 10.1016/j.thromres.2007.12.005. Epub 2008 Jan 30.
Effects of the blood coagulation vitamin K as an inhibitor of arterial calcification.
Wallin R1, Schurgers L, Wajih N.
Author information
Abstract
INTRODUCTION:

The transformation of smooth muscle cells (VSMCs) in the vessel wall to osteoblast like cells is known to precede arterial calcification which may cause bleeding complications. The vitamin K-dependent protein MGP has been identified as an inhibitor of this process by binding BMP-2, a growth factor known to trigger the transformation. In this study, we determined if the vitamin K-dependent Gla region in MGP by itself can inhibit the growth factor activity of BMP-2 and if menaquinone-4 (MK4) regulates gene expression in VSMCs.
MATERIALS AND METHODS:

A synthetic gamma-carboxyglutamic acid (Gla) containing peptide covering the Gla region in human MGP was used to test its ability to inhibit BMP-2 induced transformation of mouse pro-myoblast C2C12 cells into osteoblasts. MK4 was tested by microarray analysis as a gene regulatory molecule in VSMCs.
RESULTS AND CONCLUSIONS:

The results show that the Gla - but not the Glu-peptide inhibited the transformation which provide evidence that the Gla region in MGP is directly involved in the BMP-2/MGP interaction and emphasizes the importance of the vitamin K-dependent modification of MGP. From the data obtained from the microarray analysis, we focused on two quantitatively altered cDNAs representing proteins known to be associated with vessel wall calcification. DT-diaphorase of the vitamin K-cycle, showed increased gene expression with a 4.8-fold higher specific activity in MK4 treated cells. Osteoprotegrin gene expression was down regulated and osteoprotegrin protein secretion from the MK4 treated cells was lowered to 1.8-fold. These findings suggest that MK4 acts as an anti-calcification component in the vessel wall.

PMID:
18234293
[PubMed - indexed for MEDLINE]
PMCID:
PMC2529147
 
dsade said:
Sorry I missed this...It looks like keeping your vitamin K intake at a reasonable recommended level will prevent calcification in the VSMCs and act as a protective agent. but it/s dependent upon the MK4 form.

I would say that overall a normal intake of Vitamin K (the below indicates dairy and meat as sources) will be protective without inhibiting BMP-2's contribution to muscle growth.
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No problem, thanks for the reply. It puts me at ease knowing that Vit. K won't interfere with this pathway much. I did have another question, this time about the high dose of vitamin E. Since antioxidants are thought to reduce adaption to exercise by reducing ROS mediated signalling, is the anabolic stimulus provided by the BMP's enough to not need to worry about that pathway?
 
BMP signaling is not really dependent on that initial rush of ROS to trigger protein synthesis.
 
How long do you recommend to use BMP? I remember seeing some of the beta threads and they were stating it got better as they used it. I'm deciding whether to do 2 8 week cycles or just 1 long 16 week cycle.
 
ma70 said:
How long do you recommend to use BMP? I remember seeing some of the beta threads and they were stating it got better as they used it. I'm deciding whether to do 2 8 week cycles or just 1 long 16 week cycle.
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ma70 if I remember correctly, he said there is no reason to cycle it
 
Hey guys,
For the powder. It says 825 grams twice a day. Does anyone know what this converts into when speaking about teaspoon/tablespoon? I am awaiting my delivery but was trying to figure out ahead of getting it. Much appreciated.
 
kwinslow said:
Hey guys,
For the powder. It says 825 grams twice a day. Does anyone know what this converts into when speaking about teaspoon/tablespoon? I am awaiting my delivery but was trying to figure out ahead of getting it. Much appreciated.
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If you've ordered recently, there should be a scooper for ya.
 
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