2021 overview of my research thus far:
This is what it does for me, you may be different, get baseline and mk677 "insulin-like growth factor 1" tests done on yourself.
25mg mk677 = GH and IGF readings = 4.0 iu pharm grade GH from China for the first 2 to 3 weeks...then the body kicks in a self-regulating mechanism to keep the levels from getting to high, this is good imho, as this helps to keep glucose levels normal which I have tested yearly, always normal.
25mg mk677 = GH and IGF readings = 3.4 iu pharm grade GH from China from week 3 onward to 6th month.
25mg mk677 = GH and IGF readings = 3.2 iu pharm grade GH from China during 8th month.
At this point (7th to 8th month) I always stop using the mk677 so that it will remain effective for the next year, there is also not any point imho of continuing past the 8th month, as levels start to decline slightly from the high peak after the 6th month. This always indicates to me that it is time to stop, and then re-start again next year, around 4 months or so later.
IGF-1 range for my age group of 48 ------- 67 to 205 ng/ml igf-1
IGF-1 range for older adults ----------------- 59 to 225 ng/ml igf-1
IGF-1 range for young adults is ------------ 116 to 358 ng/ml igf-1
4-6-18, baseline igf -1 = 227 ng/ml------------------------------------------------- baseline
4-11-18, 2 days on 4iu of pharm grade HGH from China = 380 ng/ml--------------increase of 153 points
4-25-18, 2 weeks on mk677 only = 372 ng/ml------------------------------------increase of 145 points (nearly 150 point increase only lasts 2 to 3 weeks)
9-7-18, 6 months on mk677 only = 322 ng/ml------------------------------------increase of 95 points
11-2-18, 8 months on mk677 only = 304 ng/ml-----------------------------------increase of 75 points (levels start to fall after 6 months on mk677)
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new year:
3-18-19, 4 weeks on mk677 only = 327 ng/ml-------------------------------------increase of 100 points, (2-22-19 thru 3-18-19 thus far)
Year 2018 = 322 ng/ml igf-1 (level at 6 months on 25mg mk677 in morning) is equivalent of 3.4 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me.
Year 2019 = 327 ng/ml igf-1 (after 1 month on 25mg mk677 in the am) is equivalent to 3.4 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me. Used 8 months from March - Oct 2019.
2-3-20, baseline igf-1 = 229 ng/ml igf-1------------------------------------------new baseline
2-24-20, began mk677 early morning dosage again (25mg), did not take a blood reading on mk677 year of 2020 as ran out of funds in account. Used it till end of Sept 2020.
Photos:
(1) baseline from 4-6-18 = 227
(2) baseline from 2-3-20 = 229
(3) Pharm grade Chinese GH, 4-11-18 on 4iu after 2 days = 380
(4) 2 weeks on mk677, 4-25-18 = 372
(5) 6 months on mk677, 9-17-18 = 322
(6) 8 months on mk677, 11-2-18 = 304 (levels begin to drop from peak after 6 months just like in the study)
(7) 1 month on mk677, 3-18-19 = 327 (this 100 point increase is the level that is seen after 1 month, and also at 6 months)
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new year:
1-15-2021 began taking 25mg mk677 again, will use for 7 months at least.
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Observed notes over 4 years:
1) I only recommend it to people who don't experience lethargy on it, those like myself.
2) MK677 runs me only 1/7th the price of China pharm grade HGH. See coupons for 6 different places on post #374.
2) As Matsuo noted, "It’s hard to control BP with high test and MK, same as with high test and GH..."
Noticed slightly increased blood pressure (still in normal range) while using 200-225mg TRT test a week with mk677, but when I decreased my test dose to 140mg for several weeks, completely normal BP of 115 to 125 when in combo with the mk677, which is what I will continue to use from now on.
It's possible to keep your blood pressure normal while on 10 week cycle once to twice a year while using MK677 with low dose test with primobolan. I use 140mg test cyp a week TRT all year long with a yearly cycle of 500 to 600mg primobolan...no water retention, high quality muscle gain which you keep most of, no blood pressure issues, next to zero sides, great mood & no greater hair loss than testosterone, suggest home brew primo, as then it is inexpensive.
The Primobolan compilation:
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Is Primo Worth it for men?
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3) I'm 52 but 25mg of mk677 for 7 months of the year gives me the GH and igf levels of a gifted 18 year old. When I use it: high nitrogen retention, increased endurance, increased gains in gym, good pumps and full feeling in muscles, smart drug like brain enhancements (best smart drug imho), no lethargy. Look even better for the spring and summer & fall when I go to the waterpark every year with summer pass, where I used to lifeguard ages ago. Dreams are enhanced (vivid and pleasant) and even quite colorful at times with deep sleep while on it. The colorized dreams occasionally really shocked me as I never dream in color normally.
4) When I speak of the smart drug like effects of MK677, have noticed it improves my cognition, sharper focus with eyesight, able to work longer, smarter and harder at work, focus with ease, stay up later into the night if I desire, and retain a more pleasant outlook on life in general throughout the day, good anti-depressant qualities in other words, synergizes very well with daily fish oil capsules (DHA & EPA) taken for the brain.
5) Favorite supplements: Arachidonic acid (4 caps or 1400mg) taken pre-workout on workout days only, not necessary to take it daily studies show for 2 month cycle, only on workout days, then can be used month after month, year long, incredible pumps, greater lean muscle gains compared to placebo. 6 grams HMB daily, BCAA's preworkout and daily, CLA 2g taken before meals = 6g daily, 6 capsules arginine & ornithine 500mg/250mg preworkout for increased natural GH during workout, been using since age 20. Betaine 1.25g x twice a day, CLA + betaine = amazing synergy, 6 capsules fish oil, chromium picolinate, vanadyl sulfate, R-Alpha Lipoic Acid (R-alpha Lipoic acid = 300mg/S-alpha Lipoic acid = 250mg).
See ergo-log.com website for studies on all the above supplements when used by weight lifters compared to placebo. Or see post #275 for studies.
Favorite protein: 60g met-rx pure protein at once. I love 300g cold chicken salad for lunch many days...90g protein, chop and add celery, green onions, olives and use 1.5 tablespoon Better Body Foods 100% pure avacado oil Mayo in place of mayo. Keto diet daily is my favorite and fasting after 8 hours combined with cardio x 3 times a week is one of my favorite things to follow, get at least 1g protein per lb of bodyweight. I still get all my meals in within the 8 hour period when follow the fasting. When not fasting, will add in boiled egg whites when get home.
Favorite study:
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DarrenG29 said:
Mk677 hunger is unbelievable can swallow so much food down it’s not even funny
massive fullness along with it
Did you ever check your blood sugar while running mk677 I would run metformin or long acting insulin along with it if your blood sugar is high upon waken fasted
Yes, agree. Great muscle fullness. The increased hunger dies down for me every year after 4 weeks on it.
6) Sept 2018 labs (measured during 7month of taking mk677 daily) reveal labs to be completely normal for insulin sensitivity, and this was without taking +R-ALA or berberine. I have since added +R-ALA supplement the previous year & this year however (one before at least 2 of 3 meals). +R-ALA is also great post-workout, studies show the ability of +R-ALA to enhance insulin action on glucose metabolism in skeletal muscle, esp in those with some form of developed insulin resistance.