UPDATE:
year 2022, Part II: please post here:
Thread continued here with 7 blood works taken with mk677 over a 5 year period, like 4iu of pharm grade HGH:
Please post here! give us your experiences.
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Compilation of MK677 bloodwork results
What we are finding is that some people using MK677 and having bloodwork done are testing around the equivalent of 3iu of GH, and some lucky individuals are testing as high as the equivalent of 4iu of GH.
I had baseline IGF-1 bloodwork done (227), tested 4iu of Chinese pharm grade GH after 3 days (380), and am currently on a 4 week run of 15mg MK677 by itself, when I will have bloodwork done in several weeks to do a comparison as well, when I will report back with bloodwork.
After a week, I am a fan of MK-677, I weigh my own caps (as the taste is terrible) with a 1mg scale, and prefer taking it 1st thing in the morning, function fine on it, have a sense of wellbeing, muscle-fullness + pumps, increased recovery from workouts + anti-aging benefits as I am 48. It does feel like several IU of GH to me. Personally, I sleep very well at night by taking it in the morning. Yes, there is some appetite increase, but the fat percentage has actually gone down by 1% allready on the MK677 + year-round keto diet except for 25g carbs 1 hour pre-workout (always from crunchy peanut butter, glycemic index of 14) and postworkout on workout days. I consume 180g of protein a day, with 50g of that from met-rx daily and fats are kept high. Non-workout days carbs are kept to less than 20g. The peanut butter helps to give me energy for the workout. Also on TRT of 200mg test c a week as well, with 1/8th to 1/4mg armidex twice a week with each 100mg shot. I continue to loose fat while fat free mass is up. Also happy to report that blood pressure is normal. I own two books on HGH: "Grown young with HGH" and "Growth Hormone Secretagogues in Clinical Practice", both books have a discussion about the results and benefits of MK677, and how it was discovered.
Very long time reader, first time poster in this section, lifted for 15 years in my youth, age now is 49, started lifting again several months ago, thank goodness for muscle memory, making great progress again.
I just got the results back after using a chinese generic (pharm grade) for only 3 days, I did the testing improperly, as I later read you are supposed to be "on it" for at least 2 weeks before testing IGF-1, but here are my results anyways. I will post the actual labs when I get home.
Anyhow, I took 4iu on Sunday, 3iu on monday, then took tuesday off (24 hours), then took a 4iu shot into shoulder in the morning and had bloods pulled 2 hours later, my baseline was igf-1 of 227 ng/ML [high] (ref range for my age is 67 to 205) and the bloodwork after the 4iu shot of GH came back 380 igf-1, so that was a rise of 153, not bad for only around 2 days "on". Looks to be around 95 point jump per each 1iu. In the future I will use the stuff for 3 weeks straight at 4iu, and then have a proper "stable igf-1" bloodwork done.
The Beauty of Modern Science: Ibutamoren (MK-677) - Mind And Muscle
hxxp://mindandmuscle.net/articles/beauty-modern-science-ibutamoren-mk-677/
I have read of one person (Fitraver) who posted bloodwork with a 135 point IGF-1 increase with using just 12.5mg of MK677. I am just curious if I can get the same reading with 15mg after several weeks. MrSaturatedfat when from 232 igf1 to 312 igf1 on 25mg, thebigone went from 150 to 242 igf1 on 20mg and machine5150 went from 141 to 217 igf1 on 20mg. Sayitaintsoap went to 376 igf1 from an unknown baseline. Simply google their names + words mk677 + bloodwork to read more.
If I can get a good reading off several weeks of MK-677 (say an 80 to 100 point increase), I think I would then alternate it monthly (one month gh only, one month mk677 only) with the 4iu a day (5 on 2 off) of GH in order to save funds.
Here are the results of the research I did so far:
------------
self:
227 igf1---->380 igf1 (4iu chinese generic pharm grade) = 153 point jump
Peptides:
-----------
Alpha6164's (medical doctor's best friend):
167 igf1---->272 igf1 (100mcg grf(1-29) + 100mcg ghrp2 x 3 times a day) = 105 point increase
MK677:
---------
Fitraver:
224 igf1---->359 igf1 (12.5mg mk677) = increase of 135 points*
MrSaturatedfat:
232 igf1---->312 igf1 (25mg mk677) = increase of 80 points**
thebigone:
150 igf1---->242 igf1 (20mg mk677) = increase of 92 points***
machine5150:
141 igf1-----217 igf1 (20mg mk677) = increase of 76 points****
Sayitaintsoap:
unknown igf1---->376 igf1 (25mg mk677) = unknown increase*****
*See Fitraver post "bloods on 12.5mg mk677"
**See Mrsaturatedfat post "37 days on mk677"
***See thebigone post "Humatrope,MK677 and other GH labs for you guys"
****See machine5150 post "MK677 Before and After Blood Work w/ IGF Levels Raised 53.9%"
*****See sayitaintsoap post "THT's MK-677 review and blood work"
**Notice the similar point jumps between peptides and mk677, either one seems to reach a max of around 100 igf-1 points.
Anyhow, I now switched to only 15mg a day of Mk677, and will use this for 3 weeks, then have my bloodwork done so I can compare it to the 4iu of GH.
p.s. I have a question: I have read of several brothers who take a lesser dose of GH (around 2iu) with 10 to 15mg of Mk677 and report great progress, and that it saves them money. But I cannot understand how this works, as I would think the body would then detect the high amount of circulating igf-1 from the GH, which would then in turn tell the pulse from the mk677 to "not work". But this appears not to be the case...why is this so? MK677 can only reach say an increase of 75 to 100 extra IGF-1 points, and never above this as the body self-regulates it according to already circulating IGF. I just don'tunderstand how the two can be taken together and apparently work so well? I don't plan on doing this, just wondering.
------------------------------------------------------------
ref 1: additional information on mk677 only:
A few favorite quotes on Mk-677 at lower dosage:
Cybersage (from forum):
Alpha6164 (medical doctor and bodybuilder, from the long 60 page thread at prof muscle, he performed nearly a dozen bloodtests and charged them to his medical practice):
year 2022, Part II: please post here:
Thread continued here with 7 blood works taken with mk677 over a 5 year period, like 4iu of pharm grade HGH:
25mg MK677 bloodwork FAQ = 4iu pharm grade HGH (used 25mg mk677 for 6 months out of the year for 5 years straight with 7 bloodworks) - AnabolicMinds.com
This is 2022 part II of the giant part I (50,000 view) 2018 MK677 thread: https://anabolicminds.com/community/threads/bloodwork-study-of-4iu-gh-vs-peptides-mk677-similar-to-2-3-iu-gh.302178/ Please post here! Give us your experiences. Smont said: There is no amount of mk that will make it...
anabolicminds.com
-------------------------------------------------------------------------------------------
-------------------------------------------------------------------------------------------
Compilation of MK677 bloodwork results
What we are finding is that some people using MK677 and having bloodwork done are testing around the equivalent of 3iu of GH, and some lucky individuals are testing as high as the equivalent of 4iu of GH.
I had baseline IGF-1 bloodwork done (227), tested 4iu of Chinese pharm grade GH after 3 days (380), and am currently on a 4 week run of 15mg MK677 by itself, when I will have bloodwork done in several weeks to do a comparison as well, when I will report back with bloodwork.
After a week, I am a fan of MK-677, I weigh my own caps (as the taste is terrible) with a 1mg scale, and prefer taking it 1st thing in the morning, function fine on it, have a sense of wellbeing, muscle-fullness + pumps, increased recovery from workouts + anti-aging benefits as I am 48. It does feel like several IU of GH to me. Personally, I sleep very well at night by taking it in the morning. Yes, there is some appetite increase, but the fat percentage has actually gone down by 1% allready on the MK677 + year-round keto diet except for 25g carbs 1 hour pre-workout (always from crunchy peanut butter, glycemic index of 14) and postworkout on workout days. I consume 180g of protein a day, with 50g of that from met-rx daily and fats are kept high. Non-workout days carbs are kept to less than 20g. The peanut butter helps to give me energy for the workout. Also on TRT of 200mg test c a week as well, with 1/8th to 1/4mg armidex twice a week with each 100mg shot. I continue to loose fat while fat free mass is up. Also happy to report that blood pressure is normal. I own two books on HGH: "Grown young with HGH" and "Growth Hormone Secretagogues in Clinical Practice", both books have a discussion about the results and benefits of MK677, and how it was discovered.
Very long time reader, first time poster in this section, lifted for 15 years in my youth, age now is 49, started lifting again several months ago, thank goodness for muscle memory, making great progress again.
I just got the results back after using a chinese generic (pharm grade) for only 3 days, I did the testing improperly, as I later read you are supposed to be "on it" for at least 2 weeks before testing IGF-1, but here are my results anyways. I will post the actual labs when I get home.
Anyhow, I took 4iu on Sunday, 3iu on monday, then took tuesday off (24 hours), then took a 4iu shot into shoulder in the morning and had bloods pulled 2 hours later, my baseline was igf-1 of 227 ng/ML [high] (ref range for my age is 67 to 205) and the bloodwork after the 4iu shot of GH came back 380 igf-1, so that was a rise of 153, not bad for only around 2 days "on". Looks to be around 95 point jump per each 1iu. In the future I will use the stuff for 3 weeks straight at 4iu, and then have a proper "stable igf-1" bloodwork done.
The Beauty of Modern Science: Ibutamoren (MK-677) - Mind And Muscle
hxxp://mindandmuscle.net/articles/beauty-modern-science-ibutamoren-mk-677/
I have read of one person (Fitraver) who posted bloodwork with a 135 point IGF-1 increase with using just 12.5mg of MK677. I am just curious if I can get the same reading with 15mg after several weeks. MrSaturatedfat when from 232 igf1 to 312 igf1 on 25mg, thebigone went from 150 to 242 igf1 on 20mg and machine5150 went from 141 to 217 igf1 on 20mg. Sayitaintsoap went to 376 igf1 from an unknown baseline. Simply google their names + words mk677 + bloodwork to read more.
If I can get a good reading off several weeks of MK-677 (say an 80 to 100 point increase), I think I would then alternate it monthly (one month gh only, one month mk677 only) with the 4iu a day (5 on 2 off) of GH in order to save funds.
Here are the results of the research I did so far:
------------
self:
227 igf1---->380 igf1 (4iu chinese generic pharm grade) = 153 point jump
Peptides:
-----------
Alpha6164's (medical doctor's best friend):
167 igf1---->272 igf1 (100mcg grf(1-29) + 100mcg ghrp2 x 3 times a day) = 105 point increase
MK677:
---------
Fitraver:
224 igf1---->359 igf1 (12.5mg mk677) = increase of 135 points*
MrSaturatedfat:
232 igf1---->312 igf1 (25mg mk677) = increase of 80 points**
thebigone:
150 igf1---->242 igf1 (20mg mk677) = increase of 92 points***
machine5150:
141 igf1-----217 igf1 (20mg mk677) = increase of 76 points****
Sayitaintsoap:
unknown igf1---->376 igf1 (25mg mk677) = unknown increase*****
*See Fitraver post "bloods on 12.5mg mk677"
**See Mrsaturatedfat post "37 days on mk677"
***See thebigone post "Humatrope,MK677 and other GH labs for you guys"
****See machine5150 post "MK677 Before and After Blood Work w/ IGF Levels Raised 53.9%"
*****See sayitaintsoap post "THT's MK-677 review and blood work"
**Notice the similar point jumps between peptides and mk677, either one seems to reach a max of around 100 igf-1 points.
Anyhow, I now switched to only 15mg a day of Mk677, and will use this for 3 weeks, then have my bloodwork done so I can compare it to the 4iu of GH.
p.s. I have a question: I have read of several brothers who take a lesser dose of GH (around 2iu) with 10 to 15mg of Mk677 and report great progress, and that it saves them money. But I cannot understand how this works, as I would think the body would then detect the high amount of circulating igf-1 from the GH, which would then in turn tell the pulse from the mk677 to "not work". But this appears not to be the case...why is this so? MK677 can only reach say an increase of 75 to 100 extra IGF-1 points, and never above this as the body self-regulates it according to already circulating IGF. I just don'tunderstand how the two can be taken together and apparently work so well? I don't plan on doing this, just wondering.
------------------------------------------------------------
ref 1: additional information on mk677 only:
A few favorite quotes on Mk-677 at lower dosage:
Cybersage (from forum):
Sandpig: (9/6/2017)Yes, Fitraver saw an over 100 point increase while running it at 12.5mg (half dose)
Elvia1023: (19,000 posts)Drop down to 12.5 . Eventually the lethargy and other issues will slowly fade. Once they do, you can bump it up again. Took me two months at 12.5 before I could go to 25.
RamboStallone (9/6/2017: 7,000 posts):Everyone responds differently but 25mg is far too much for you. Others are fine at that dose but most aren't. I would recommend 10-12.5mg and with that the side effects will be minimized but the results still there. You won't be as full and pumped but you will feel multiple times better. 10-12.5mg is great for muscle fullness, pumps, recovery, size and strength. I am fine at 10mg but once I get to 15mg and over I can barely function and the fatigue is unbearable. I actually prefer MK-677 to HGH in many ways... especially for gaining size.
ref 2: additional information on peptides only:This is why I personally recommend starting at 5mg. MK677 increases gh/igf levels for a 24hr period from a single dose, this is longer than any other peptide or GH product, and in my opinion stronger than any gh supp including exogenous GH. I've used this stuff for years now and everytime I restart it anything over 5mg puts me on my ass. It's all the sides of increased gh/igf just more pronounced with MK677 then any other gh product including the effects. I blow up on the stuff immediately. The cts is unbearable. My recommendation, lower the dose brother.
Alpha6164 (medical doctor and bodybuilder, from the long 60 page thread at prof muscle, he performed nearly a dozen bloodtests and charged them to his medical practice):
Alpha6164 saidI dont think peptides in usual 2-3x daily can equal 5iu of quality GH daily. Here is why. When i was on 5iu of Rips daily, my IGF was in the 600s. That is coming from a baseline of 160s. We know from three different tesamorelin studies that 2mg of tesamorelin raised IGFs 109-180 from basline. So if i started with 160 i could go to 260-340. Now that is a great number from baseline and can be almost a 200% increase and you will get fat loss benefits, anti-aging etc. But definitely not in the range of 5iu of synthetic GH.
My best friend and partner was on 100/100mcg of GRF/GHRP-2 three times a day and his IGF increased about 120 from baseline. So very in line with 2mg of tesamorelin.
Alpha6164 in conclusion said:My best friend used GRF1-29/ghrp-2 100/100 three times daily and his IGF went from 167 to 272 in 8 weeks. Yes we are not getting IGFs in the 500-700s as with high dose GH but having a rise of 40% on such a small dose is pretty significant.
ref3: will post 1st two bloodwork results when get home.Peptides will raise your GH as if you were on 2-3iu of synthetic GH daily. So it is great for people that wanna be on anti-aging dosage or for fast loss purposes.
Using a 100/100mcg combo 3x daily will raise your IGF similar to if you were on 2-3iu of GH daily. Most people on 4iu of GH will have IGFs in the high 300s to low 400s. But raising your IGF by 100-150 points from baseline can only help you with better recovery, healing, metabolism etc.
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