Betaine ideal dosing?

uubiduu

Well-known member
I want to take 2.5g daily. What do you think is the best time for taking it? Pre-Workout or on an empty stomach? With PWO shake?
 
All pre-workout if you can handle it (GI distress).
 
Ya go pre-workout and 2.5 shouldn't be too rough. It was only when I went above that dose that I got hit with some GI issues, but still nothing crazy.
 
I had no idea it was a PWO dose. I've been doing a gram 3 times a day. Interesting.
 
uubiduu said:
Would also like to know! Started it some hours ago and it hit me hard GI wise no joke.
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The worst is explosive poops on squat days...
 
rob112 said:
Is there acute effects? Or is it saturation though?
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It really doesn't matter when you take it....pre, post, etc., with or without food. Its well absorbed and the results are due to chronic use (i.e.: it being taken up and stored by the muscles). Excretion of actual betaine is incredibly low. Working on a review of the performance enhancing effects of betaine and a deep speculation into mechanisms. Hoping to have it submitted early in '14.
 
ZiR RED said:
It really doesn't matter when you take it....pre, post, etc., with or without food. Its well absorbed and the results are due to chronic use (i.e.: it being taken up and stored by the muscles). Excretion of actual betaine is incredibly low. Working on a review of the performance enhancing effects of betaine and a deep speculation into mechanisms. Hoping to have it submitted early in '14.
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Awesome. I look forward to that.
 
ZiR RED said:
It really doesn't matter when you take it....pre, post, etc., with or without food. Its well absorbed and the results are due to chronic use (i.e.: it being taken up and stored by the muscles). Excretion of actual betaine is incredibly low. Working on a review of the performance enhancing effects of betaine and a deep speculation into mechanisms. Hoping to have it submitted early in '14.
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Insane!Looking forward to read this.
 
ZiR RED said:
It really doesn't matter when you take it....pre, post, etc., with or without food. Its well absorbed and the results are due to chronic use (i.e.: it being taken up and stored by the muscles). Excretion of actual betaine is incredibly low. Working on a review of the performance enhancing effects of betaine and a deep speculation into mechanisms. Hoping to have it submitted early in '14.
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You the man. I will say there is some evidence that preworkout dosing may positively affect the hormonal profile while weight training. Mild effects
 
mr.cooper69 said:
You the man. I will say there is some evidence that preworkout dosing may positively affect the hormonal profile while weight training. Mild effects
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Is that like the possible IGF mimicking? I thing that is what I seem before.
 
mcc23 said:
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$25 for the Full text. Looks interesting.
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There's a number of studies in pigs showing betaine increases GH production. There is one human study that shows this as well (Apicella et al., 2013 (2012?)). There is 1 animal study that shows betaine is taken up by the hypothalamus and inturn increases GHrP secretion, which is one of the mechanisms behind the increase in GH. I believe there is also another study that shows betaine increases hepatic GH binding and the resultant IGF-1 release. All of the animal studies were with chronic (6+ weeks) and the Apicella study was 2 weeks.

Cooper,can you link me to the acute studies where betaine increases the hormonal response to exercise?
 
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