Best GDA?

I just remember in most every past thread on gda/ nutrient practitioners that ive seen the majority of people claimed need2slin was the best they have used by a large margin.
 
caino said:
Ssv2 got even more man
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I'm a big SSv2 fan, however I was just commenting on his choice of R-ALA instead if Na-R-ALA. :)

I'd even suggest the bulk route with Na-R-ALA. 300mg + 1-2g ALCAR is great for AMPk activation and nutrient partitioning.
 
Seriously can't wait for Glycophase to be released. It's a really solid formula and will be a great option for guys not wanting to spend a lot.
 
I just bought Burn 24.

If it sucks I am going to get all the other heavy rep hitters to neg train the Omega reps. ;)
 
Anyone have access to this article?:
[h=1]Mechanism of action of natural products used in the treatment of diabetes mellitus.[/h] Invalid Link Removed
 
jerrysiii said:
Anyone have access to this article?:
[h=1]Mechanism of action of natural products used in the treatment of diabetes mellitus.[/h] Invalid Link Removed
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The only "aid" with diabetics that has been proven is cinnamon I believe.
 
mtinsideout said:
What about apple cider vinegar and green tea?
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Has been studied for lowering blood sugar for treatment of pre diabetics

I don't believe its been studied on diabetics specifically.
 
mr.cooper69 said:
There have been tons
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I know there are a lot of studies in type 2 and borderline type 2. Cinnamon has been studied a **** ton on type 1. Ill have to look again later.
 
pyrobatt said:
I know there are a lot of studies in type 2 and borderline type 2. Cinnamon has been studied a **** ton on type 1. Ill have to look again later.
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The difference is really non-existent, with the primary difference being insulin-dependence vs independence in early stage type II diabetics. Some examples are jiagolan, berberine, oleuropein, etc
 
mr.cooper69 said:
The difference is really non-existent, with the primary difference being insulin-dependence vs independence in early stage type II diabetics. Some examples are jiagolan, berberine, oleuropein, etc
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coop educates me again. Ill do some research when I get home.
 
jimbuick said:
I'm down.

Which ones are omega reps anyway? :evil:
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Cj and Haiz. :D

I like Burn24 quite a bit so I hope Ben doesn't upset his stomach again. :(
 
bolt10 said:
Cj and Haiz. :D

I like Burn24 quite a bit so I hope Ben doesn't upset his stomach again. :(
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My stomach is fragile lol.

It arrives tomorrow. I better let stop negging people so I am on full charge, just in case. ;)
 
Coop or someone more knowledgeable than me: What are your thoughts on Salacia oblonga extract? Is this study saying that the compound expresses selective GLUT-4 translocation?: Invalid Link Removed

Seems like the ideal ingredient, but I don't see it listed in any GDA.
 
jerrysiii said:
Coop or someone more knowledgeable than me: What are your thoughts on Salacia oblonga extract? Is this study saying that the compound expresses selective GLUT-4 translocation?: Invalid Link RemovedSeems like the ideal ingredient, but I don't see it listed in any GDA.
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Where does it say it's selective?

Also, mangifern has virtually 0 oral bioavailability
 
jerrysiii said:
I only see the summary. The conclusion mentions muscle cells but does not mention adipose. So I assumed selective. Is the extract not administered orally in the study?
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Never, ever jump right to the conclusions. The methods state that they assayed glut4 translocation for muscle cells ONLY. What counts is this:

"S. oblonga extract increased 2-deoxy-D-glucose uptake by 50% in L6-myotubes and 3T3-adipocytes."
 
mr.cooper69 said:
Never, ever jump right to the conclusions. The methods state that they assayed glut4 translocation for muscle cells ONLY. What counts is this:

"S. oblonga extract increased 2-deoxy-D-glucose uptake by 50% in L6-myotubes and 3T3-adipocytes."
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Thanks for the clarification. Seems like a pretty good insulin mimic though.
 
I'm considering dropping GDA's until I wrap up this phase of keto, I don't see much benefit to keeping them in or am I wrong? Kept them in originally just because they had become part of my routine after proving effective with carb meals. But as it stands I am <50 carbs a day and if I took a GDA with my weekly refeed I think that would somewhat defeat it's purpose. Am I correct in these assumptions?

Currently using SSv2. Have AP and Recompadrol on hand.
 
Driven2lift said:
I'm considering dropping GDA's until I wrap up this phase of keto, I don't see much benefit to keeping them in or am I wrong? Kept them in originally just because they had become part of my routine after proving effective with carb meals. But as it stands I am <50 carbs a day and if I took a GDA with my weekly refeed I think that would somewhat defeat it's purpose. Am I correct in these assumptions?

Currently using SSv2. Have AP and Recompadrol on hand.
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This makes a lot sense to me. I'd suggest a whole body workout prior to your carb-up. Given the ultra-low carb diet, you should already be in a very good state to take in carbohydrate. The whole body workout would just be a plus.
 
Driven2lift said:
I'm considering dropping GDA's until I wrap up this phase of keto, I don't see much benefit to keeping them in or am I wrong? Kept them in originally just because they had become part of my routine after proving effective with carb meals. But as it stands I am <50 carbs a day and if I took a GDA with my weekly refeed I think that would somewhat defeat it's purpose. Am I correct in these assumptions?

Currently using SSv2. Have AP and Recompadrol on hand.
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Correct. I would either drop the GDA or dose it pre-bed for GH release which would be nice.
 
mr.cooper69 said:
Still wouldn't make it selective, ppar y certainly plays a role in glucose -> adipose
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I gotta find that study I have talking about ppar y partial agonist being good for insulin sensitivity without the added weight gain.

I know I have it! Probably in my write up somewhere
 
EBF Inc said:
As a full agonist. Yes.
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If you look at the study he posted, mangiferin had an equivalent effect on glucose transport into myotubes vs adipose.

In the end it won't matter because mangiferin has been documented to barely permeate the rat intestinal epithelium. The story is likely much worse in humans
 
mr.cooper69 said:
If you look at the study he posted, mangiferin had an equivalent effect on glucose transport into myotubes vs adipose.

In the end it won't matter because mangiferin has been documented to barely permeate the rat intestinal epithelium. The story is likely much worse in humans
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I'd have to look.

But it acts as an alpha glucosodase inhibitor which is one action along with ppar activity
 
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