Tell SNS What You Would Like to See From Us (2020 Edition)

A DHT Booster

For Anti-aging:
NMN + Resveratrol+ PQQ + Gotu Kola + fisetin


For the libido
Cnidium Monnieri made me nauseous

I didn't like Stinging Nettle and Maca, because they haven't done much for me. Instead try adding pygeum and Vitex. Pygeum increase my loads. Vitex suppose to that too but never tried it.

Mucuna non-extract, because of the L-Dopa. Although I think Vitex might also act on dopamine receptors.

In my expirence

Effect/$:
Longjack > Tribulus
Fadogia > Bulbina


For Probiotic Formula:
Probiotic bacteria LKM512 seems to help for life extension
 
aaronuconn said:
My vote is for taurine. Fits well with the premise of the product. How about coconut water powder?
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I was leaning towards Taurine or Citrulline.

I thought about coconut water powder but my fear is that there are quite a few people allergic to coconut and I want something that pretty much anyone can use. Plus, I don't want every flavor to have a coconut taste.
 
GQdaLEGEND said:
taurine def. how about inositol
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Inositol would be possible. Curious as to your suggested reasoning on this over Taurine just out of curiosity.
 
aaronuconn said:
How about L-Ornithine L-Aspartate with the electrolytes? Could be a good addition to the product. Idk about taste, though
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I thought about that because I love the ingredient. The taste isn't bad at all; it's just not a cheap ingredient and may would add to the price more than some of the other things we are talking about.
 
Resolve10 said:
This was my first thought haha

Agreed.

Ornithine HCL doesn't have too much taste IIRC, need to get around to LOLA myself.

What about Glutamine + Alanine? Doesn't Alanine have a sweeter taste too? I know Sustamine has research for hydration benefits and increased electrolyte uptake, but also know it is a bit expensive. Unsure how bonded (Sustamine) vs L-Alanine + Glutamine compares.
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Glutamine/Alanine would add too much to the price if we did and effective dose and would make it taste a little chalky. Branded Sustamine is ridiculously expensive.

I wasn't expecting Glycine suggestions. I'm definitely open to that.
 
aaronuconn said:
Much interest in Testofen? Feel like I remember this back in the day.

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I don't know of anyone it ever really sold well for. I thought about it a long time ago but it would almost have to be a single ingredient product bc the price is so expensive.
 
aaronuconn said:
New study on Palmitoylethanolamide and muscle recovery.

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Great ingredient. If anyone is interested in this, let me know.

We would have to get creative with the naming since we already have a PEA-500 Xtreme that is a different ingredient and this one is abbreviated PEA as well.
 
sns8778 said:
Glutamine/Alanine would add too much to the price if we did and effective dose and would make it taste a little chalky. Branded Sustamine is ridiculously expensive.

I wasn't expecting Glycine suggestions. I'm definitely open to that.
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listening to the customers and giving them what they want is why I've been a sns/cel loyal customer for all these many years...how many years have you been with sns/cel now STEVE?...it's got to be a bunch!!!!
 
mik95 said:
A DHT Booster

For Anti-aging:
NMN + Resveratrol+ PQQ + Gotu Kola + fisetin


For the libido
Cnidium Monnieri made me nauseous

I didn't like Stinging Nettle and Maca, because they haven't done much for me. Instead try adding pygeum and Vitex. Pygeum increase my loads. Vitex suppose to that too but never tried it.

Mucuna non-extract, because of the L-Dopa. Although I think Vitex might also act on dopamine receptors.

In my expirence

Effect/$:
Longjack > Tribulus
Fadogia > Bulbina


For Probiotic Formula:
Probiotic bacteria LKM512 seems to help for life extension
Click to expand...

For DHT boosters, I think Epiandrosterone is a great option. Some good choices are:
- Competitive Edge Labs Stano-Plex 300 (Epiandro + VASO6)
- Muscle Addiction EpiAndro300 (straight Epiandro)
- Muscle Addiction EpiAndro Lean (Epiandro + KSM-66 + Paradoxine)
- Xtreme Performance Gels EpiAndro Gel

We use Vitex in Inhibit-P and some people experience great libido increases with it. (Also has Mucuna in it which you mentioned above also)

Never tried Pygeum; would be curious if other people that have have seen similar results.

Thank you for the probiotic suggestion. Will look into that one.
 
thebigt said:
listening to the customers and giving them what they want is why I've been a sns/cel loyal customer for all these many years...how many years have you been with sns/cel now STEVE?...it's got to be a bunch!!!!
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Thank you for the kind words and support.

SNS - since 2004.
CEL - since 2007.
 
thebigt said:
listening to the customers and giving them what they want is why I've been a sns/cel loyal customer for all these many years...how many years have you been with sns/cel now STEVE?...it's got to be a bunch!!!!
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We always love having your support BigT! Steve is 100% customer focused in every single product decision he makes.

That's one of the reasons I love SNS.
 
Jiigzz said:
We always love having your support BigT! Steve is 100% customer focused in every single product decision he makes.

That's one of the reasons I love SNS.
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steve and I used to talk all the time about formestane, back when cel was going to release td formestane[I believe cel was the 1st to release a td formestane once e-form got discontinued]. we have had many discussions over the years-a really great guy!!!
 
Any interest in Robuvit?

I think @Resolve10 has used it with success previously (IIRC).

“Contrary to Belcaro et al. (2014), who has found improvement of mood in chronic fatigue syndrome patients administered with Robuvit 200 mg daily for 6 months, we have found significant mood improvement in volunteers without fatigue syndrome—after 4-week administration of Robuvit in higher dose (300 mg/day).”

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aaronuconn said:
Any interest in Robuvit?

I think @Resolve10 has used it with success previously (IIRC).

“Contrary to Belcaro et al. (2014), who has found improvement of mood in chronic fatigue syndrome patients administered with Robuvit 200 mg daily for 6 months, we have found significant mood improvement in volunteers without fatigue syndrome—after 4-week administration of Robuvit in higher dose (300 mg/day).”

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Improvement in Mood, Oxidative Stress, Fatigue, and Insomnia Following Supplementary Management With Robuvit

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thebigt said:
@sns8778 how about a product designed to reduce RBC?
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I'd be interested to hear ingredient suggestions. I'm open to most any ideas if there is enough interest.
 
aaronuconn said:
Any interest in Robuvit?

I think @Resolve10 has used it with success previously (IIRC).

“Contrary to Belcaro et al. (2014), who has found improvement of mood in chronic fatigue syndrome patients administered with Robuvit 200 mg daily for 6 months, we have found significant mood improvement in volunteers without fatigue syndrome—after 4-week administration of Robuvit in higher dose (300 mg/day).”

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Very expensive ingredient to use in a formulation. I considered it s a single ingredient but not sure if there is enough demand for it.
 
Resolve10 said:
This is interesting, hadn't seen this! PEA has some other interesting studies, but this intrigues me. Can't seem to find a Levagen branded product here in the US (I didn't look super hard), but there are quite a few options for standard PEA. May do some more reading today now.
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From the full text:

"There were no main effects of treatment or time by treatment interactions for muscle soreness or thigh circumference."

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"Myoglobin concentration peaked +1 h after exercise and declined thereafter (p < 0.01; Figure 5). Myoglobin concentration was lower for the PEA than placebo group at +1, +2, and +3 h post exercise (p < 0.05). Creatine kinase peaked +24 h after exercise and decreased thereafter (p < 0.05). There was no change in lactate dehydrogenase over time. There were also no main effects of treatment or time by treatment interactions for creatine kinase and lactate dehydrogenase (Table 2)."

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"There were no main effects of time or treatment for interleukin-6 and 10 (Table 2), demonstrating that these inflammatory markers were not changed by the exercise. Tumor necrosis factor-α peaked post exercise and declined thereafter (p < 0.05), but there were no main effects of treatment or time by treatment interactions (Table 2)."

"Protein kinase B phosphorylation peaked immediately after exercise for the PEA group only (p < 0.05; Table 3) and returned to baseline values 1 h after exercise. There were no main effects of time or treatment for: cAMP response element-binding protein, extracellular signal-regulated kinases 1/2, c-Jun N-terminal kinases, nuclear factor kappa-light-chain-enhancer of activated B cells, p38 mitogenactivated protein kinases, ribosomal protein S6 kinase beta-1, and signal transducer and activator of transcription 3 and 5 (Table 3), demonstrating that these phosphoprotein signaling pathways were not induced by the exercise."

Pretty underwhelming results overall. There are a few limitations to this study and I would not run out to supplement PEA based this alone.
 
SweetLou321 said:
From the full text:

"There were no main effects of treatment or time by treatment interactions for muscle soreness or thigh circumference."

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"Myoglobin concentration peaked +1 h after exercise and declined thereafter (p < 0.01; Figure 5). Myoglobin concentration was lower for the PEA than placebo group at +1, +2, and +3 h post exercise (p < 0.05). Creatine kinase peaked +24 h after exercise and decreased thereafter (p < 0.05). There was no change in lactate dehydrogenase over time. There were also no main effects of treatment or time by treatment interactions for creatine kinase and lactate dehydrogenase (Table 2)."

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"There were no main effects of time or treatment for interleukin-6 and 10 (Table 2), demonstrating that these inflammatory markers were not changed by the exercise. Tumor necrosis factor-α peaked post exercise and declined thereafter (p < 0.05), but there were no main effects of treatment or time by treatment interactions (Table 2)."

"Protein kinase B phosphorylation peaked immediately after exercise for the PEA group only (p < 0.05; Table 3) and returned to baseline values 1 h after exercise. There were no main effects of time or treatment for: cAMP response element-binding protein, extracellular signal-regulated kinases 1/2, c-Jun N-terminal kinases, nuclear factor kappa-light-chain-enhancer of activated B cells, p38 mitogenactivated protein kinases, ribosomal protein S6 kinase beta-1, and signal transducer and activator of transcription 3 and 5 (Table 3), demonstrating that these phosphoprotein signaling pathways were not induced by the exercise."

Pretty underwhelming results overall. There are a few limitations to this study and I would not run out to supplement PEA based this alone.
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Great post. I'm more intrigued by Palmitoylethanolimide based on feedback from people that I know and trust even than from the data myself. Demand wise in general, we are getting asked for this some.
 
Something I have been interested in is the potential of the N-phenylpropenoyl-L-amino acids N-caffeoyldopamine and N-coumaroyldopamine being able to provide similar effects to other proven beta-2-agonists, which can promote muscle hypertrophy and decreased fat mass. Now I know these were trialed in Compound 20 by USPLabs back in the day and are the supposed actives in the Cocoabuterol on the market now. I know this is likely to not get a lot attention due to these products not being the highest reviewed items and there is no human data proving efficacy. I think dosing and bioavailability and limitations of these options though. These compounds seem to be either not well absorbed, broken down by COMT, or altered by the gut microbiome. I think it would be cool to see what a product providing these with something to enhance absorption and help prevent microbiome alterations would do, it could be combined with EGCG to try and alter the COMT activity in peripheral tissues as well. This more of me nerding out then anything, cool potential class of compounds though.

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Edit: I see there were others mentioning interest in this ingredient in this thread. I will look around at other methods to potentially enhance bioavailability besides ECGC.

Further edit:

It seems that N-phenylpropenoyl-L-amino acids are either not absorbed well, conjugated via COMT, hydrolyzed in the liver, and because they ae not absorbed well by the small intestine they can remain in the GI tract where there are altered by the gut bacteria in the large intestine then the metabolites are absorbed. I would think the adding piperine and EGCG with these compounds could lead to greatly enhanced product. Piperine could inhibit hydrolysis in the liver and potentially enhance absorption across the gut barrier of the small intestine which would leave less to be metabolized by the microbiome. The EGCG as stated before could inhibit COMT peripherally.

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sns8778 said:
I'd be interested to hear ingredient suggestions. I'm open to most any ideas if there is enough interest.
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not exactly sure what ingredients would be used to lower RBC, I've heard grape seed extract but other than that I really haven't researched it enough to name ingredients...

not sure about general population, but pretty sure there would be interest on this forum if you were to come up with a effective formula!!!

as far as marketing you could call it a general wellness supplement and market it that way to the yoga dudes, lol.
 
I have compiled a list of supplements that allegedly reduce RBC, but I cannot attest to these products actually working.
 
Beau said:
I have compiled a list of supplements that allegedly reduce RBC, but I cannot attest to these products actually working.
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well then submit them already, lol....:geek:
 
DMB/Naringen/Grapefruit
Inositol Hexaphosphate (IP6)
Alpha Lipoic Acid
Green Tea/Green Tea Extract
Losartan (prescribed pharma product)
Tyrosine (possibly, but without its co-factors B6 and C)
Vitamin K2 (MK7)
Nattokinase
Quercetin
Curcumin
 
Beau said:
DMB/Naringen/Grapefruit
Inositol Hexaphosphate (IP6)
Alpha Lipoic Acid
Green Tea/Green Tea Extract
Losartan (prescribed pharma product)
Tyrosine (possibly, but without its co-factors B6 and C)
Vitamin K2 (MK7)
Nattokinase
Quercetin
Curcumin
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you get this @sns8778 ? @Beau no grape seed extract?
 
Grapefruit and grapefruit seed extract is spoken about frequently.

I know GSE has benefit, I just don't know if it is hematocrit related. I will have to look.
 
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Beau said:
Grapefruit and grapefruit see extract is spoken about frequently.

I know GSE has benefit, I just don't know if it is hematocrit related. I will have to look.
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TBH I haven't invested much time to research, I was being lazy and leaving it up to @sns8778 to do the heavy lifting.
 
mik95 said:
Are you guys bring more nootropics to market?

May be you can do a CILTEP stack
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CILTEP is about as weak of a formula you can find for the price. If SNS puts out more nootropic products I hope they are nothing like CILTEP. Just my opinion of course.
 
ELROCK said:
CILTEP is about as weak of a formula you can find for the price. If SNS puts out more nootropic products I hope they are nothing like CILTEP. Just my opinion of course.
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Couldn’t agree more, focus XT blows that out of the water. Lately I’ve been having great effects mixing my energized aminos with focus XT
 
What is CILTEP ?
and agree focus XT is one of the best nootropic out there .. better suited for “gamers” too
 
GQdaLEGEND said:
What is CILTEP ?
and agree focus XT is one of the best nootropic out there .. better suited for “gamers” too
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CILTP is Chemically induced Long term potentiation, it's from another forum

PDE 4 and others inhibition:

2x450 mg Artichoke Extract. Other artichoke extract brands have been reported to work too.

cAMP Increase:

4mg of Forskolin

Dopamine Metabolism Support (Important for avoiding fatigue due to increased dopamine metabolism!):

500mg Phenylalanine (Lower doses work better for some)
B-Vitamin Complex
200mg Caffeine (Optional)

For mitigating forskolin's effects on Acetylcholinesterase:

800mg ALCAR (Generally 200mg of ALCAR for every 1mg of forskolin)

An earlier recommendation before we started adding ALCAR to counteract forskolin's effects was to take the following in the afternoon:

350mg Jarrow N-Acetyl L-Tyrosine (Possibly no longer necessary)
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mik95 said:
CILTP is Chemically induced Long term potentiation, it's from another forum
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Looks very meh. I also don’t know where you’d find 4mg of Forskolin given it’s typically dosed in 25mg increments. That’s also a oddly specific number for ALCAR, given it’s usually in increments of either 500mg or 750mg. Could always use bulk powder, but that’s a hassle to measure it to those specific milligrams.
 
aaronuconn said:
Looks very meh. I also don’t know where you’d find 4mg of Forskolin given it’s typically dosed in 25mg increments. That’s also a oddly specific number for ALCAR, given it’s usually in increments of either 500mg or 750mg. Could always use bulk powder, but that’s a hassle to measure it to those specific milligrams.
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was thinking the same... a bit of a strange formula and nothing that strikes me as even relatively special (even looking comprehensively vs just one-by-one).

100% would take focus xt or even some of the solo noots SNS offers over that.
 
Beau said:
Grapefruit and grapefruit seed extract is spoken about frequently.

I know GSE has benefit, I just don't know if it is hematocrit related. I will have to look.
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thebigt said:
TBH I haven't invested much time to research, I was being lazy and leaving it up to @sns8778 to do the heavy lifting.
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I'll be glad to look into this when I have the time. I'm spread super thin and pretty much behind at life at the current moment haha.
 
mik95 said:
Are you guys bring more nootropics to market?

May be you can do a CILTEP stack
Click to expand...

We are open to doing more nootropics as long as they are compliant and there is a demand for them.

I am not impressed at all with the CILTEP Stack to be honest with you. I think Focus XT is a better product in pretty much every regards to that.

ELROCK said:
CILTEP is about as weak of a formula you can find for the price. If SNS puts out more nootropic products I hope they are nothing like CILTEP. Just my opinion of course.
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I agree. CILTEP has good marketing behind it but it appears to be intentionally designed to be a VERY inexpensive product to make in order to allow for a high markup for marketing purposes. Not knocking the concept, that's the way a lot of products in this industry are now.

mik95 said:
CILTP is Chemically induced Long term potentiation, it's from another forum
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That seems like part of their marketing (which they are very good at).

You can compare the ingredients to Focus XT and Focus XT contains a ton more active ingredients all at efficacious dosages.

aaronuconn said:
Looks very meh. I also don’t know where you’d find 4mg of Forskolin given it’s typically dosed in 25mg increments. That’s also a oddly specific number for ALCAR, given it’s usually in increments of either 500mg or 750mg. Could always use bulk powder, but that’s a hassle to measure it to those specific milligrams.
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4 mg. of Forskolin has not data on it that I'm aware of. It is a very expensive ingredient and it seems like is just thrown in there at a low dosage to have it on the label. Not knocking them, a lot of brands do that.

Focus XT has plenty of ALCAR in it and for anyone wanting more they can always use ALCAR-500.

https://seriousnutritionsolutions.com/products/focus-xt-series/
Use code anabolicminds20 to save 20% off.

FocusXT Label (Storming Grape Limeade) Supp Facts.png
 
Beau said:
DMB/Naringen/Grapefruit
Inositol Hexaphosphate (IP6)
Alpha Lipoic Acid
Green Tea/Green Tea Extract
Losartan (prescribed pharma product)
Tyrosine (possibly, but without its co-factors B6 and C)
Vitamin K2 (MK7)
Nattokinase
Quercetin
Curcumin
Click to expand...

Great list. Thank you.
 
just ordered sns phenibut and inhibit-e...just sayin
 
I just wanted to let anyone following the thread know that we extended our Memorial Day sale thru Sunday. Invalid Link RemovedInvalid Link Removed
 
Bumping for any update on the viability of these suggestions.

Especially interested in that possibility of a 50 or 60% Icariin product. Thanks.
 
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