Modifilan - Fucoidan, Fucoxanth, Fucothin
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One of the most impressive aspects of Modifilan that sets it apart from other types of seaweed products is its very high content of soluble polysaccharides like Fucoidan, laminarin and alginate. The former compound is particularly rich in such simple sugars as glucuronic acid, mannose and fucose that give Laminaria its distinctive taste.
The ongoing research into Fucoidan has conclusively demonstrated its ability to induce cancer cell apoptosis (programmed cell death) in leukemia, stomach and colon cancer cell lines. This biological data support epidemiological observations that Laminaria is an important factor contributing to the relatively low breast cancer rates reported in Japan.
It has also been demonstrated that Fucoidan acts as a so-called activator of the reticulo-endothelial system, specifically as an enhancer of phagocytosis. This suggests another aspect of antitumor activity of Fucoidan related to the activation of macrophage-mediated tumor cell killing.
There are also non-polysaccharide fractions from Laminaria that have been found to have a significant cancer-preventative anti-mutagenic (anti-DNA damage) activity against typical genotoxic substances.
Another promising use of the sulfated polysaccharides Fucoidan and laminarin is in the prevention and treatment of cardiovascular disease. Several mechanisms are involved: the inhibition of smooth muscle cell proliferation (monoclonal hyperplasia) which is an important step in atherogeneses; activation of enzymes involved in the beta-oxidation of fatty acids which can be useful in the prevention and treatment of hyperlipedemia. Laminarin has been shown to have a hypotensive effect. It also exhibits 30% of the anticoagulant activity of heparin.
All of these properties of sulfated polysaccharides make Modifilan clinically applicable in the prevention and treatment of coronary heart disease, cerebrovascular disease, atherosclerosis, cancerogenesis and cancer metastasis.
The non-digestible polysaccharide alginate that comprises 50% of Modifilan's total dry weight has the unique ability of binding heavy metals and radioactive substances to its own molecules. As the alginate is non-digestible it is excreted from the body together with toxic compounds. This is particularly important for cadmium and mercury, as these metals are found at dangerously high levels in air, water and food. Alginate can also remove isotopes that have previously been absorbed by the human body from the environment. Even small amounts of radioactive pollution will expose surrounding cells to harmful radioactive emission.
At the Cardiovascular Center at the Sakhalin Hospital, patients were given up to ten grams of Modifilan every day for three months. The results showed:
a. Decrease of cholesterol by 26.5%
b. Decrease of B-lipoproteins by 25.1%
c. Decrease of triglycerides by 32.1%
No negative reactions were found in the kidneys, the liver and other organs. No side effects were found.
As a result of scrupulous scientific and clinical examination MODIFILAN was officially recognized as a leading prophylactic nutritional product by government of Russia. On November 12, 1997 our product was given State Certificate of Recommendation, approved by Ministry of Health. Following is the original content of that document:
RECOMMENDATIONS
For use of the preventive food supplement MODIFILAN in ecologically polluted regions.
1. Title: Modifilan (tablets, powder).
2. Ingredients: polysaccharides (alginate, Fucoidan, seaweed fibers), vitamins A, B1, B2, B3, B12, C, E, macro- and micro-elements (iodine, manganese, magnesium, iron, calcium, chromium, selenium, zinc, etc.)
oh yeah, in addition to killing cancer, it also helps you loose weight by bumping your metabolism, ala dnp. It's also one of the key ingredients in pyrogenx, anthony roberts and protein factory's new/next fat burner. Modifilan is the highest concentration of fucoidan/fucoxanth/fucothin that I've been able to locate.
I would be curious to hear your opinion of this stuff. It might be a product worth carrying. It's also supposed to be one of the most potent antioxidants available.