The APEX "suggestion box"

[CATdiesel76]

I'm not sure that a stim would work the same way in a TD. I liked me some Clearshot too

As for producing new DS... I have a family now...

I did come up with a theoretical ROS for the compound you're talking about that I'd love to test just to see if I did it right.

gotcha didn’t know if any non transdermal products were an option hence the clearshot. I’d be scared to rub that stuff on me…

 

[ELROCK]

I am still working on some old bottles of Triton. Personally I love the stuff! Is the new version as effective as the previous version?

 

[Renew1]

I am still working on some old bottles of Triton. Personally I love the stuff! Is the new version as effective as the previous version?

Sure!

The carrier has been dramatically improved, but the active compound is still as effective as before.

 

[BigGame84]

I am still working on some old bottles of Triton. Personally I love the stuff! Is the new version as effective as the previous version?

The endurance is incredible. I've only been using it when I know I am working out an hour later after I apply. Most days I apply TD's at 7am but don't work out until 5pm, so I don't bother with Triton on those days. Just not sure of the half-life.

 

[ELROCK]

The endurance is incredible. I've only been using it when I know I am working out an hour later after I apply. Most days I apply TD's at 7am but don't work out until 5pm, so I don't bother with Triton on those days. Just not sure of the half-life.

You liking the new version as much as the previous version?

Yeah, I only use it on workout days I can apply it 1 hour before the workout.

 

[JKVol]

I'm not sure that a stim would work the same way in a TD. I liked me some Clearshot too

As for producing new DS... I have a family now...

I did come up with a theoretical ROS for the compound you're talking about that I'd love to test just to see if I did it right.

I’m your guy

 

[nostrum420]

I’m your guy

You can do HPLC?

 

[JKVol]

You can do HPLC?

Oh no… I meant your Guinea Pig

 

[Marne40]

Is Helioplex still in the works? Apologies if I missed any updated info for it, been slacking in here.

 

[schizm]

Iirc a compound similar to ursolic acid is being worked on, bring it!

 

[Rich Tits]

Probably the best recommendation I can now make for the longevity of your product line would be the removal of the essential oils from your carrier. I say this because there is a breadth of evidence suggesting that the two that you use are known to be allergenic following repeated exposure. More personally, (anecdotal evidence ik ik) two of my family members and my friend had developed a delayed hypersensitivity reaction (Allergic contact dermatitis) following chronic use of helios. Ideally, I'd like to avoid incurring the possibility myself given my intent in running your products as staples. While I can't offer a percentage of your consumer base that will develop a reaction, I can say that on the individual level that the probability of developing one increases with continued use. Rambling aside, I appreciate your consideration.

 

[xR1pp3Rx]

Probably the best recommendation I can now make for the longevity of your product line would be the removal of the essential oils from your carrier. I say this because there is a breadth of evidence suggesting that the two that you use are known to be allergenic following repeated exposure. More personally, (anecdotal evidence ik ik) two of my family members and my friend had developed a delayed hypersensitivity reaction (Allergic contact dermatitis) following chronic use of helios. Ideally, I'd like to avoid incurring the possibility myself given my intent in running your products as staples. While I can't offer a percentage of your consumer base that will develop a reaction, I can say that on the individual level that the probability of developing one increases with continued use. Rambling aside, I appreciate your consideration.

some of us find relief from dermatitis with helios and I personally have ran a minimum of 1 ml perday for probably a couple yrs strait almost. most days i run 2mls. not only that but I have been able to ditch my script for ketoconazol specifically for my dermatitis issues.

 

[Rich Tits]

some of us find relief from dermatitis with helios and I personally have ran a minimum of 1 ml perday for probably a couple yrs strait almost. most days i run 2mls. not only that but I have been able to ditch my script for ketoconazol specifically for my dermatitis issues.

I'm sure— which is predominantly a result of the THC downregulating the inflammatory cytokines expressed by the leukocytes, especially in the area of application. I'm saying the inclusion of potential allergens where necessity doesn't exist isn't ideal

 

[xR1pp3Rx]

i understand

 

[Rich Tits]

i understand

Thanks man. I love your guys' products and swim in Helios everyday lol. It would just be troublesome to source my own THC and I'd rather avoid the hassle of macgyvering my own carrier where I can instead just get those people back on your stuff.

 

[nostrum420]

Probably the best recommendation I can now make for the longevity of your product line would be the removal of the essential oils from your carrier. I say this because there is a breadth of evidence suggesting that the two that you use are known to be allergenic following repeated exposure. More personally, (anecdotal evidence ik ik) two of my family members and my friend had developed a delayed hypersensitivity reaction (Allergic contact dermatitis) following chronic use of helios. Ideally, I'd like to avoid incurring the possibility myself given my intent in running your products as staples. While I can't offer a percentage of your consumer base that will develop a reaction, I can say that on the individual level that the probability of developing one increases with continued use. Rambling aside, I appreciate your consideration.

The issue is if you don't have something to make it smell like something other that chemicals and moonshine, people don't like that. So, when I first built my carrier I researched the most universally accepted/liked scents and I found that mint and eucalyptus were not only well liked, they were well tolerated by those who didn't specifically "like" them. Additionally, they tend to have low instances of allergic reactions and have penetration enhancing characteristics.

That all being said, there is a terpene blend I really like and it may work well at a lower inclusion rate.

 

[Rich Tits]

The issue is if you don't have something to make it smell like something other that chemicals and moonshine, people don't like that. So, when I first built my carrier I researched the most universally accepted/liked scents and I found that mint and eucalyptus were not only well liked, they were well tolerated by those who didn't specifically "like" them. Additionally, they tend to have low instances of allergic reactions and have penetration enhancing characteristics.

That all being said, there is a terpene blend I really like and it may work well at a lower inclusion rate.

I definitely should've payed more thought to why iron-legion has "lavender essentials" lol. Totally get from a business perspective the idea of the whole package transdermal scent and all, especially with compounds that are strongly odorous. I suppose I was hoping there to be feasible alternatives where odor is a concern (though I've never cared one way or another as long as it works). Thanks for looking at other avenues; it's much appreciated.

 

[schizm]

How about a dedicated skin tightening formulaTD?

 

[xR1pp3Rx]

How about a dedicated skin tightening formulaTD?

Resveros has unique skin enhancing effects.

 

[nostrum420]

How about a dedicated skin tightening formulaTD?

Maybe but if you fill your GFs vagisil bottle with it, I'm not responsible for what happens next... good or bad...

 

[schizm]

Resveros has unique skin enhancing effects.

Issss that right hmmmm, I'll check it out

 

[Kronic]

How about a dedicated skin tightening formulaTD?

does that even work? I been injecting glutathione and I don't think there's even a difference. are you turning yellow?

or is there something like melanowhite I don't know about

 

[Renew1]

Resveros, huh?
Who would like a FREE Bottle of Resveros?

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Today's Apex Gift is ....... Let's see some more Greetings for this Exciting New Product!!!

anabolicminds.com

 

[GQdaLEGEND]

Ooooooh, how I would love to but that would mean a new facility.

this is why we need AMC to reach $10k , i will invest in that facility lol

 

[Rocket3015]

Not sure this is something Apex wants to get involved in but what about a localized TD with Clen in it? I’ve never tried it before but some say it’s legit. Since this is a “suggestion” thread I thought I’d throw it out there.

I like this idea !!

 

[JKVol]

I like this idea !!

Or they could make up TD that we can buy and we could add the Clen or anything for that matter.

 

[xR1pp3Rx]

Or they could make up TD that we can buy and we could add the Clen or anything for that matter.

isnt there a carrier available somewhere? salvo or something

 

[JKVol]

isnt there a carrier available somewhere? salvo or something

Yeah but if I’m gonna spend money, I’m gonna give it to my squad.

 

[xR1pp3Rx]

Yeah but if I’m gonna spend money, I’m gonna give it to my squad.

you ARE fo sho part of the squad yo!

 

[xR1pp3Rx]

Regulators!!! mount up!!!

 

[Kronic]

Regulators!!! mount up!!!

it was a clear black night, a clear white moon

 

[Marne40]

it was a clear black night, a clear white moon

Warren G was on the streets, tryin to consume

 

[JKVol]

Honestly, I've barely taken supplements the last 5 years.

I actually have 100+ Old School PH bottles, you name it I probably have it .
I also have original Craze 1st batch, Slim Xtreme, The Original DMAA from PA, Jungle Warfare etc.

I use to buy, and just collect

I still have my whole last order from Apex, and I'm always considering buying a bunch from these BOGO deals! I'm already 103kg with little effort, and I'm seeing so many good reviews on the recomp effects I thought I may give it a shot soon.

Would you be interested in unloading some of your goodies?

 

[Rocket3015]

Everything has a price ..............

 

[JKVol]

Don’t know if this is even possible at all but since we are throwing out crazy ideas, what about a TD appetite suppressant?

 

[Rocket3015]

Don’t know if this is even possible at all but since we are throwing out crazy ideas, what about a TD appetite suppressant?

Interesting idea

 

[xR1pp3Rx]

maybe a 6-paradol TD would be cool too!

 

[Cheeky Monkey]

Transdermal Nootropic? (Is that even possible?)

 

[schizm]

Probably mentioned before already but would be awesome to see a multi-angled formula that targets fat on the midsection, similar to what Evo's Eviserate/smolder did/does.

 

[JKVol]

Probably mentioned before already but would be awesome to see a multi-angled formula that targets fat on the midsection, similar to what Evo's Eviserate/smolder did/does.

For core fat loss, AndroLo was pretty awesome.

 

[BigGame84]

For core fat loss, AndroLo was pretty awesome.

Still have a bunch but I haven't used on my core because I am trying to ration it. Just using on my arms for now.

 

[Rocket3015]

Probably mentioned before already but would be awesome to see a multi-angled formula that targets fat on the midsection, similar to what Evo's Eviserate/smolder did/does.

In for this also !!

 

[xR1pp3Rx]

flashpoint and ursa combo perhaps? I mean would that even be similar?

 

[JKVol]

flashpoint and ursa combo perhaps? I mean would that even be similar?

I’m using both right now and they are truly amazing products.

 

[schizm]

flashpoint and ursa combo perhaps? I mean would that even be similar?

Flashpoint/Glycyrrhetinic Acid is one of the ingredients in eviscerate/smolder so some amount could def be tossed into a targeted formula for sure (just found it meh for me using it solo) but do have much love for Ursa and have just recently been experimenting with upper dosing along with on the abs.

 

[FilipeBR]

Can you do any prohormone in TD form ? Would go well with the awesome cutting stuff you guys have. Even if it's just some 11 Oxo

 

[BigGame84]

TD Ligustrazine

 

[JKVol]

TD Ligustrazine

What does this do? Never heard of it.

 

[xR1pp3Rx]

TD Ligustrazine

Ligustrazine induces viability, suppresses apoptosis and autophagy of retinal ganglion cells with ischemia/reperfusion injury through the PI3K/Akt/mTOR signaling pathway (nih.gov)


im interested in your reasoning... is this solely for eye health? or are you reaching with the mTOR pathway thing?

 

[BigGame84]

Ligustrazine induces viability, suppresses apoptosis and autophagy of retinal ganglion cells with ischemia/reperfusion injury through the PI3K/Akt/mTOR signaling pathway (nih.gov)


im interested in your reasoning... is this solely for eye health? or are you reaching with the mTOR pathway thing?

This is in several supplements. BLR Han Swolo. Olympus Labs Ep1louge... Just to name a few.

I'm going to steal from the Evomuse Top Muscle writeup to make this easier:

Ligustrazine

Next up, we’ve got a two-pronged attack from Ligustrazine—preventing muscle atrophy and promoting muscle growth. In research, there’s a few common ways to study muscle atrophy; one of them is to “denervate” a muscle, which involves clipping off the nerve supply, so it no longer gets electrical signals. I remember doing this in college biology lab, interesting stuff. You’re pretty much guaranteed a predictable amount of atrophy. Denervated rats treated with Ligustrazine lost significantly less muscle at 7, 14, and 28 days vs. control (61). Another common and reliable way to induce atrophy is to make a muscle weightless, which is referred to as “suspension”. The Ligustrazine treated rats showed significantly less muscle loss vs. control (62).

As for the second prong, Ligustrazine increases glucose uptake in muscle cells, upregulates mitochondrial biogenesis, and significantly increases BMP-7 (which is a key player in muscle growth, see BMP write-up for more info). And for a finishing move, it is a strong ROS scavenger, reduces unwanted inflammatory cytokines, and promotes vasodilation

61. Wang H, Liang B, Peng C, Wang P. [Effect of Ligustrazine on expressions of FoXO3a, MAFbx, and MuRF1 in denervated skeletal muscle atrophy rats]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi Zhongguo Xiufu Chongjian Waike Zazhi Chin J Reparative Reconstr Surg. 2012 May;26(5):597–600.
62. Zhang H, He Z, Gao Y, Hinghofer-Szalkay HG, Fan X. Muscle composition after 14-day hindlimb unloading in rats: effects of two herbal compounds. Aviat Space Environ Med. 2007 Oct;78(10):926–31.
63. Gao X, Zhao X, Zhu Y, Li X, Xu Q, Lin H, et al. Tetramethylpyrazine protects palmitate-induced oxidative damage and mitochondrial dysfunction in C2C12 myotubes. Life Sci. 2011 Apr 25;88(17–18):803–9.
64. Yuan X, Liu L, Fu Q, Wang C. Effects of ligustrazine on ureteral obstruction-induced renal tubulointerstitial fibrosis. Phytother Res PTR. 2012 May;26(5):697–703.