bdcc said:Very interesting section on experimental cryotherapy for fat loss in that book.
About cold baths if I'm
Correct? Freezing fat cells or bringing them out to burn them so To speak. If I am correct, is that the 12 or more carbon fat cells? Long chain fatty acids?
Dermatol Surg. 2009 Jul 13.
Cryolipolysis for Noninvasive Fat Cell Destruction: Initial Results from a Pig Model.
Zelickson B, Egbert BM, Preciado J, Allison J, Springer K, Rhoades RW, Manstein D.
Department of Dermatology, University of Minnesota Medical School, Minneapolis, Minnesota.
BACKGROUND Liposuction is one of the most frequently performed cosmetic procedures in the United States, but its cost and downtime has led to the development of noninvasive approaches for adipose tissue reduction. OBJECTIVE To determine whether noninvasive controlled and selective destruction of fat cells (Cryolipolysis) can selectively damage subcutaneous fat without causing damage to the overlying skin or rise in lipid levels. METHODS Three Yucatan pigs underwent Cryolipolysis at 22 sites: 20 at cooling intensity factor (CIF) index 24.5 (-43.8 mW/cm(2)), one at CIF 24.9 (-44.7 mW/cm(2)), and one at CIF 25.4 (-45.6 mW/cm(2)). Treated areas were evaluated using photography, ultrasound, and gross and microscopic pathology. Lipids were at various times points. One additional pig underwent Cryolipolysis at various days before euthanasia. RESULTS The treatments resulted in a significant reduction in the superficial fat layer without damage to the overlying skin. An inflammatory response triggered by cold-induced apoptosis of adipocytes preceded the reduction in the fat layer. Evaluation of lipids over a 3-month period following treatment demonstrated that cholesterol and triglyceride values remained normal. CONCLUSIONS Cryolipolysis is worthy of further study because it has been shown to significantly decrease subcutaneous fat and change body contour without causing damage to the overlying skin and surrounding structures or deleterious changes in blood lipids.
Aesthetic Plast Surg. 2009 Jul;33(4):482-8. Epub 2009 Mar 19
Clinical efficacy of noninvasive cryolipolysis and its effects on peripheral nerves.
Coleman SR, Sachdeva K, Egbert BM, Preciado J, Allison J.
Department of Surgery, NYU School of Medicine, 44 Hudson Street, New York, NY, 10013, USA, [email protected].
BACKGROUND: Cryolipolysis provides a method for noninvasive fat reduction that significantly reduces subcutaneous fat in a pig model without apparent damage to skin and surrounding structures. This study aimed to determine whether fat reduction in humans caused by cold exposure is associated with alteration in local sensory function or nerve fibers. METHODS: In this study, 10 subjects were treated with a prototype cooling device. Fat reduction was assessed in 9 of the 10 subjects via ultrasound before treatment and at the follow-up visit. Sensory function was assessed by neurologic evaluation (n = 9), and biopsies (n = 1) were collected for nerve staining. RESULTS: Treatment resulted in a normalized fat layer reduction of 20.4% at 2 months and 25.5% at 6 months after treatment. Transient reduction in sensation occurred in six of nine subjects assessed by neurologic evaluation. However, all sensation returned by a mean of 3.6 weeks after treatment. Biopsies showed no long-term change in nerve fiber structure. There were no lasting sensory alterations or observations of skin damage in any of the subjects evaluated. CONCLUSION: Noninvasive cryolipolysis results in substantial fat reduction within 2 months of treatment without damage to skin. The procedure is associated with modest reversible short-term changes in the function of peripheral sensory nerves.
PMID: 19296153
Cryolipolysis for subcutaneous fat layer reduction.
Avram MM, Harry RS.
Dermatology Laser & Cosmetic Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. [email protected]
BACKGROUND AND OBJECTIVE: Cryolipolysis is a unique non-invasive method for the selective reduction of fat cells with controlled, localized cooling. It is important, therefore, to understand the potential efficacy and safety of this new procedure for fat layer reduction. MATERIALS AND METHODS: A review of the literature associated with cryolipolysis was performed to evaluate the findings from pre-clinical and clinical studies with respect to the mechanism of action, efficacy, and safety. RESULTS: Cryolipolysis has demonstrated efficacy in both human and animal studies. Histology findings also confirm the selective reduction of fat in both humans and animals, with evidence of a gradual thinning of the fat layer over a period of two to four months. Importantly, cryolipolysis has not produced any significant adverse side effects in studies to date and any noted effects have been minor and temporary. CONCLUSION: Although the mechanism of action for cryolipolysis is not yet completely understood, the efficacy and safety of this non-invasive procedure for fat layer reduction has been demonstrated in the studies available to data. Further studies willl assist in identifying the mechanism and elucidate the full potential of this technology to perform safe, non-invasive fat reduction for areas of local fat accumulation. Copyright 2009 Wiley-Liss, Inc.
Cryolipolysis for Reduction of Excess Adipose Tissue.
Nelson AA, Wasserman D, Avram MM.
Division of Dermatology, UCLA Medical Center, Los Angeles, CA.
Controlled cold exposure has long been reported to be a cause of panniculitis in cases such as popsicle panniculitis. Cryolipolysis is a new technology that uses cold exposure, or energy extraction, to result in localized panniculitis and modulation of fat. Presently, the Zeltiq cryolipolysis device is FDA cleared for skin cooling, as well as various other indications, but not for lipolysis. There is, however, a pending premarket notification for noninvasive fat layer reduction. Initial animal and human studies have demonstrated significant reductions in the superficial fat layer thickness, ranging from 20% to 80%, following a single cryolipolysis treatment. The decrease in fat thickness occurs gradually over the first 3 months following treatment, and is most pronounced in patients with limited, discrete fat bulges. Erythema of the skin, bruising, and temporary numbness at the treatment site are commonly observed following treatment with the device, though these effects largely resolve in approximately 1 week. To date, there have been no reports of scarring, ulceration, or alterations in blood lipid or liver function profiles. Cryolipolysis is a new, noninvasive treatment option that may be of benefit in the treatment of excess adipose tissue. Copyright © 2009 Elsevier Inc.
Very interesting section on experimental cryotherapy for fat loss in that book.
Basically, you induce frost bite in the adipose tissue without harming the skin (different cellular composition and blood flow patterns between skin and adipose allow for skin to maintain temps better). To do this, a skin fold is "sucked out" and exposed to cold between two metal plates . Apoptosis (death) in the fat cells ensues, and results in the breakdown of this tissue by macrophages, its transport into the blood, and its eventual excretion. Following a few sessions, the results are seen over several months, usually about a 25% reduction in skin fold thickness.
Br
No, its called cryolipolysis, and its a clinical procedure similar to liposuction but non-invasive.Basically, you induce frost bite in the adipose tissue without harming the skin (different cellular composition and blood flow patterns between skin and adipose allow for skin to maintain temps better). To do this, a skin fold is "sucked out" and exposed to cold between two metal plates . Apoptosis (death) in the fat cells ensues, and results in the breakdown of this tissue by macrophages, its transport into the blood, and its eventual excretion. Following a few sessions, the results are seen over several months, usually about a 25% reduction in skin fold thickness.Br
The process he experimented with in the book is not the same as this, it is much more basic.
Performed on himself with skinfold measures taken and dietary calories tracked.
bdcc said:You obviously haven't read the book, it is nothing about cold baths at all!![]()
No need to apologise! We are all here to learn. What was the conclusion that he came up with? I have never heard of him.Apologies... Was a topic on paleo solution I got mixed up with. Matt LaLonde did a section on this
In this New York best seller, Tim Ferriss claims that he gained 34lbs of muscle in 4 weeks. Here is what I think
I have the book
I will post up some excerpts from the ice treatments he suggest