SPP Presents: Abliderate Advanced

dsade said:
Abliderate Advanced is primarily used to target VAT while also helping to eliminate the estrogenic component. It's also designed to help with Insulin sensitivity and to inhibit fatty acid uptake in abdominal fat. It also has a higher concentration of 7-oxo.

Good stuff!
 
Abliderate Advanced is primarily used to target VAT while also helping to eliminate the estrogenic component. It's also designed to help with Insulin sensitivity and to inhibit fatty acid uptake in abdominal fat. It also has a higher concentration of 7-oxo.

Okay,so should I just not bother buying the OG version?
 
Abliderate Advanced is primarily used to target VAT while also helping to eliminate the estrogenic component. It's also designed to help with Insulin sensitivity and to inhibit fatty acid uptake in abdominal fat. It also has a higher concentration of 7-oxo.

Although the burn for the Eviscerate smolder is not all that bad, I notice no real burn sensation from the Abliderate Advanced.
 
What risks is someone looking at if someone chooses to run abliterate advanced year round? Just curious.
 
^ I doubt there would be any "risks" running this year round. However, I think it's probably best if this is cycled. Continuous use might ware off the effects. Dsade would have the correct answer...
 
The only risk you take is skin drying in the area of application. If you pick up a good moisturizer (like BoBu) you should be able to keep irritation down.
 
Ok I've been doing this for a week now and I love it. When I apply the AA I go next to the AC and the cold air makes my skin right. Feels great. Not sure if it enhances it in any way lol but it sure tightens up. Might want to give it a try guys
 
Had my first application today after exfoliating with Java soap. I didnt feel any burning, I would call it more of a warming sensation. After about 5 minutes, wow did I feel my mid-section start tightening up. It was a pretty awesome feeling. Looking forward to continuing use and seeing the results. 2 bottles worth.
 
Abliderate Advanced is primarily used to target VAT while also helping to eliminate the estrogenic component. It's also designed to help with Insulin sensitivity and to inhibit fatty acid uptake in abdominal fat. It also has a higher concentration of 7-oxo.

how many grams in 7-oxo original v/s advanced?
 
Had my first application today after exfoliating with Java soap. I didnt feel any burning, I would call it more of a warming sensation. After about 5 minutes, wow did I feel my mid-section start tightening up. It was a pretty awesome feeling. Looking forward to continuing use and seeing the results. 2 bottles worth.

You shouldn't see any burn with Abliderate Advanced. The capsaicin is responsible for the burn in Eviscerate/Smolder and it isn't in Abliderate Advanced. Keep us updated on your results though, I simply love the product!
 
  • Marie-Noëlle Dieudonné, Anes Sammari, Esther Dos Santos, Marie-Christine Leneveu, Yves Giudicelli, René Pecquery
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  • The Journal of Steroid Biochemistry and Molecular Biology, Volume 101, Issue 1, September 2006, Page 85
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[h=2]Abstract[/h]Adipose tissue is an important site of steroid hormone biosynthesis, as type I 11β-hydroxysteroid dehydrogenase (HSD1), the enzyme responsible for the conversion of cortisone into cortisol and the P450 aromatase, the enzyme catalysing androgens aromatization into estrogens, are both expressed in human adipose tissue. In the present report, we have investigated the possibility that sex steroids and leptin could regulate these two enzymes in cultured preadipocytes from men and women intra-abdominalfat depots.
In women preadipocytes, human recombinant leptin down-regulates HSD1 mRNA expression (−58%) and P450 aromatase activity (−26%). Conversely, leptin up-regulates the HSD1 (2.4-fold) and the P450 aromatase (1.6-fold) mRNA expression in men preadipocytes. In women preadipocytes, 17β-estradiol strongly stimulates HSD1 mRNA expression (10-fold) and, in contrast, decreases by half the P450 aromataseexpression. In men, 17β-estradiol has no influence on HSD1 expression but up-regulates P450 aromatase mRNA expression (2.4-fold). Finally, androgens increase by a factor of 2.5–5 the mRNA expression of both enzymes in men.
These findings suggest that sex steroids and leptin either increase or decrease local cortisol and estrogens productions in men or in women preadipocytes, respectively. They also indicate that steroid metabolism in adipose tissue is controlled by a coordinated regulation of P450 aromatase and HSD1 expressions. Finally, the important sex-specific differences described herein may also contribute to explain the sexual dimorphism of body fat distribution in humans.
 
  • Marie-Noëlle Dieudonné, Anes Sammari, Esther Dos Santos, Marie-Christine Leneveu, Yves Giudicelli, René Pecquery
  • Invalid Link Removed
  • The Journal of Steroid Biochemistry and Molecular Biology, Volume 101, Issue 1, September 2006, Page 85
  • Invalid Link Removed

[h=2]Abstract[/h]Adipose tissue is an important site of steroid hormone biosynthesis, as type I 11β-hydroxysteroid dehydrogenase (HSD1), the enzyme responsible for the conversion of cortisone into cortisol and the P450 aromatase, the enzyme catalysing androgens aromatization into estrogens, are both expressed in human adipose tissue. In the present report, we have investigated the possibility that sex steroids and leptin could regulate these two enzymes in cultured preadipocytes from men and women intra-abdominalfat depots.
In women preadipocytes, human recombinant leptin down-regulates HSD1 mRNA expression (−58%) and P450 aromatase activity (−26%). Conversely, leptin up-regulates the HSD1 (2.4-fold) and the P450 aromatase (1.6-fold) mRNA expression in men preadipocytes. In women preadipocytes, 17β-estradiol strongly stimulates HSD1 mRNA expression (10-fold) and, in contrast, decreases by half the P450 aromataseexpression. In men, 17β-estradiol has no influence on HSD1 expression but up-regulates P450 aromatase mRNA expression (2.4-fold). Finally, androgens increase by a factor of 2.5–5 the mRNA expression of both enzymes in men.
These findings suggest that sex steroids and leptin either increase or decrease local cortisol and estrogens productions in men or in women preadipocytes, respectively. They also indicate that steroid metabolism in adipose tissue is controlled by a coordinated regulation of P450 aromatase and HSD1 expressions. Finally, the important sex-specific differences described herein may also contribute to explain the sexual dimorphism of body fat distribution in humans.
 
Just a note: VERY limited stock. Our bottle error has not been rectified yet, in spite of a ton of calls. They have less than 30 bottles to work with.
 
Once again, AA is back at the Planet and no longer sold out.
 
Just came in to profess my love of AA. I got my first bottle the first week in August and it's still not quite empty! My second bottle is stashed in my cabinet. :D
 
Just came in to profess my love of AA. I got my first bottle the first week in August and it's still not quite empty! My second bottle is stashed in my cabinet. :D

Results? It is probably my favorite product of our line.
 
Just came in to profess my love of AA. I got my first bottle the first week in August and it's still not quite empty! My second bottle is stashed in my cabinet. :D

Very cool, bro! :cool2:
 
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