Being in CA, I'm not sure if I've had a truly good cut of steak. I hear people talking about grain fed cow all the time, but I don't think I've ever had it.
Do they have costco there ...?
yes and I am a member.
ABSTRACT FROM JOURNAL OF CLINICAL ENDOCRONOLOGY AND METABOLISM
Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane (Aromasin) is a potent and selective irreversible aromatase inhibitor. To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg exemestane daily, orally, for 10 d with a 14-d washout period. Blood was withdrawn before and 24 h after the last dose of each treatment period. A PK study was performed (n = 10) using a 25-mg dose.
RESULTS :
The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 ± 24% (mean ± SD; P = 0.002 vs. baseline) and 32 ± 29% (P = 0.008) decreases in estradiol concentrations, 71 ± 12% (P < 0.0001) and 74 ± 12% (P < 0.0001) decreases in estrone concentrations, and 45 ± 27% (P = 0.004) and 51 ± 20% (P = 0.02)
There was an increase in circulating testosterone concentrations after both 25 mg (60 ± 58%; P = 0.001) and 50 mg (56 ± 48%; P = 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 ± 36%; P = 0.004) and 50 mg (47 ± 59%; P = 0.052) exemestane, respectively (Fig. 1Go and Table 2Go).
SHBG concentrations were decreased by 21 ± 7% (P = 0.0003) and 19 ± 39% (P = 0.18) at 25 and 50 mg exemestane, respectively.
Free testosterone concentrations were increased by 117 ± 74% (P = 0.0001) and 154 ± 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone.
There were no changes in circulating serum triglycerides, cholesterol, or LDL or HDL cholesterol concentrations with either dose of exemestane.
END WEEK #3
13 WEEKS OUT FROM SHOW
Week 3 was when things really started coming together..
Weight: Holding in the 189-190lb range. Still amazed that I am packing away these amounts of cals, and struggling to hold on to weight. A cheat meal was added mid-week, on a non-WO day, on top of my regular fare -- this put the total cals on that day ~5000.
Strength: I'm not one to judge & gauge effectiveness or progression by simply how much poundage I can move..still, I'm tossing around weights like they're toys. Yesterday was an intense leg session, best one yet of prep, and my ATG squats were strong, moving like a machine in there..very pleased in this department.
Stamina: After builiding myself up gradually in terms of activity first 2 weeks, I really let things all hang out during week 3. I feel, well, like a youngster again.
Libido: LOL. Well, I been focused on a great many things currently, so the "desire" part has receeded..
(the dude downstairs just hasn't been on the same page; he seems to be always on the prowl, at the slightest whim)
Drive: If there is one thing that shines out to me even with all these positive facets, it is this category. I want to hit my sessions each day with ferocity..I want to train when I'm scheduled to rest..I dream about my workouts, and I even mess up my purchases at the grocery store because I have my training on the brain.
Recovery: No letdown, continues to be impeccable, despite my brutal and intense sessions.
Discussion:
The steroidal education of (and introduction to) Snag continues, and this week I was finally able to spend some more time researching and self-edifying. And there's a reason for that (other than my normal thirst for knowledge)..
First - all the minor nusances have mostly dissipated. Night sweats are gone (my sheets are thankful), no problems peeing (was only isolated few times)..no abnormal feeling in my testicles. The one nusance that remains, is a bit of acne. Nothing bad, but my back is broke out a tad, a little on my chest (chest could also be irritation from shaving it & tanning, no biggie).
One thing that did not go away but rather increased, was L nipple irritability and swelling. And so - safeguards were put in play to combat estrogen-related side effects going forward, in the form of Aromasin (exemestane), an aromatase inhibitor. Dosing started yesterday, at 12.5mg ED. So now, I'm taking 2 steroids. (watch out, I'm off the hook)
This stuff of course was new to me, altho I see it has been around and in use for well over a decade. Very intriquing..as is the whole field of steroidal compounds. So much here to learn..
Anyway, a small bit of info on exemestane below, for those who are curious.
I also would like to make a special thanks to DreamWeaver and Finaflex for dropping some of their new preworkout product on me, Ignite 2. Again, have not been using a preWO at all to this point in prep, and I prolly won't for another week yet, but looking forward to checking this out guys..pic of product below.
Updated pics to follow later, gotta wait for the photographer.
OVERALL RATING, WEEK 3: Rolling. Like a boulder. Feel great!
Will let you know!Can't wait tio see your reaction to it...
Looking Great Bro, I think you are gonna just cruz through this cut! Looking forward to your thoughts on IGNITE-2!
That smoothness DW, is a relaxed shot, totally relaxed gut as I spread out my lats - that's why I call it my "modeling" pose (not aiming for muscularity, rather showing more of a mainstream approach).
The smoothness I'm talking about, is being deflated from my low carb day (yes, 250g carbs is my low day, LOL)..
And notes on the pics guys: of course, taken cold again. This is also a lower-carb day in my 3-day cycling pattern now (yes, I've gone and complicated things, with a cycling pattern within my already set pattern>>>>>)
It's weird, how much different I can look thruout the day let alone from day-to-day, fuller at times and more defined and flat at others - between meals even..crazy stuff.
Indeed.That's the way it is when you are lean, the water dictates the look, drives me crazy..
Small(ish) update:
I don't usually get too excited over training arms, and I certainly don't like to report back on these sessions.
But - in only the second arm-focused routine I have done in prep (arms + abs this day), I am enthused. :smoker:
DW and ScottyDoc got me curious on the Ignite 2, so I figured wth, I'll throw down 1/2 scoop and take a sneak peak..
And with that, I was off & running. I've already said every training session has been explosively awesome, but this one seemed to kick into another gear. When I pull out 12-15 sets each just to focus on bi's & tri's -- you know I am in a zone. :yup:
(abs were sufficiently annihilated too, ~250 reps on various exercises)
I just felt good..dint wanna stop blowing up the guns!
Pic, following the session.
Which one looks better fellas?
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DW and ScottyDoc got me curious on the Ignite 2, so I figured wth, I'll throw down 1/2 scoop and take a sneak peak..
And with that, I was off & running. I've already said every training session has been explosively awesome, but this one seemed to kick into another gear. When I pull out 12-15 sets each just to focus on bi's & tri's -- you know I am in a zone. :yup:
(abs were sufficiently annihilated too, ~250 reps on various exercises)
I have been interested in trying the ignite myself. looks like a good product.
My goodness....a random note here:
I am absolutely loving the way I look, upon rising, the morning after my high carb days (~500g)..
on these days I feel large indeed.
WOW.
Thanks brother..I think that's more a reflection of my hi-rep ab session yesterday, and the illusion of my little ab muscle bellies being poofed out a bit.Wow there seems to be some definitely leaning in the abdominal area since a couple of days ago...
What's up anthon88? long time no see, hope all has been well.What's up Snag! I'll definitely be keeping an eye on this log.
Food is simply a means to an end..one of the least heralded aspects of development and overall health IMO.Man your dedication on the diet really does make me re-analyze my own dedication, lol!
Sidenote this morning:
My butt looks thinner as I wake up today. Srs.
I have never had striated glutes.
I am so looking forward to the buns being shredded.. :ntome:
What's up anthon88? long time no see, hope all has been well.
Kind of a different log, than what are previous conversations have been centered around, eh?
Man your dedication on the diet really does make me re-analyze my own dedication, lol!
Actually a bit over 3.5yrs, pretty much non-stop, my own version of keto. Built in carb-ups (all-carb meal style) and scheduled cheat days.I think Snag has gone a whole year on the Keto diet before or something ungodly.
Birth of the AndroSeries
February 5, 2011 by Eric Potratz
I can recall May 15th, 2010 pretty well.
I was outside the Primordial Performance office in Portland OR with one of the original Primordial Performance investors Dustin Adler, talking about the future of the company. The discussion wasn't really about Dustin's financial interest since he had already sold off his personal shares. He was really just obsessed with business and wanted to get a feel for the core concept of the company.
"Do you feel the business is doing well?" Dustin asked me.
"Yeah, our products are pretty solid, people like them, and as soon as we pay down some of our debt we should be able to release some new products" I replied, keeping a positive spin on the question.
Dustin slowed his walk. "Do you think Primordial is the greatest in the world at what it offers?" he asked inquisitively.
Greatest at what? I thought. I took a moment to think of a worthy reply. Dustin was a longtime friend and someone I respected very much. He had insightful information on a wide variety of topics, and always had a good sense – I knew the question was leading to something.
Before I could reply, he stopped, looked straight at me, and gave me a few words I would never forget -
"Eric, if everyone at PP is going to work 80 hours per week and pour every ounce of their life into this company shouldn't it be the greatest in at least something? If you aren't distinguishing yourself then this company just isn't that special, or its not taking big enough bets. It's time to break out or get out"
It was a challenge and it struck me like a bolt of lightning.
I understood what he meant and he was right. I was dwindling and not seizing opportunity to its fullest extent. Our products were good, but they could be so much better.
But what exactly could we or should we be the greatest in the world at? We had always worked towards the concept of having a great "men's health company", but that concept was so vague. We needed something more specific. I scanned my brain for the most noteworthy products we had developed since we started, and it was clear – Primordial Performance is in the business of selling steroids.
Definition of Greatness
With a clear objective in mind, it was time to figure out what defined the world's greatest steroid.
People's goals are different, so there would be no single greatest steroid. I also knew greatness couldn't simply be defined as simply being the most powerful. Methyltrienbolone is the most powerful anabolic steroid ever created, 300x stronger than testosterone, but it can't actually be used without causing severe liver and kidney damage – and that's not so great.
Considering the goals of most users, we decided the greatest steroids in the world must meet the following requirements:
Powerful
Safe
Easy to use
Reliable
Legal
Supported by the Manufacturer
Entrenched in R&D
Suddenly, life had renewed purpose and inspiration — Project AndroSeries was underway.
I arranged a meeting with our outside consultants and manufacturing team. The message was loud and clear
"We are going to produce the greatest steroidal formula the nutraceutical and pharmaceutical industry has ever seen. We are pulling all stops and fully investing all resources"
I gathered every pertinent study I had and began tuning my steroidal cerebral. I tracked down over 200 full text scientific references on the pertinent topics – bioavailability, metabolism, pharmacokinetics, bio-equivalency, biological effects and more.
We had a number of goals to accomplish with this project, the most notable being -
✓ A product that *****s the effectiveness and safety of injectable steroids
✓ A series of products that can be stacked according to anabolic/androgenic preference
✓ An oral delivery system that effectively delivers naturally occurring steroids
✓ Increased cost effectiveness and safety over any other available steroid preparation
✓ Portability and convenient dosing (softgels)
✓ A product with a defendable legal status
At the peak of my research I had gathered so many papers, graphs, experimental notes, and info from outside consultants that I hired a personal secretary just to organize and record the information into an organized format.
Steroids & Legal Issues
As of 2011, nearly all "anabolic steroids" have been made illegal by the US congress. Anything that's not on the ban list, is still deemed illegal by default if it binds to the androgen receptor and has androgenic or anabolic effects. And if the compound is an anabolic steroid it isn't DSHEA or compliant with the FDA, DEA and USADA.
The steroid known as dehydroepiandrosterone (DHEA) is explicitly exempted from the Anabolic Steroid Control Act, because it does not activate the androgen receptor in its original DHEA form – therefore it's not an anabolic steroid – that is, until it converts.
In other words, even though DHEA has anabolic and androgenic effects those effects are not seen until it's activated in the human body. Plus, because DHEA is a naturally occurring component in the food supply, it's legal to sell as a dietary supplement.
Plain old DHEA
As bodybuilders found out over a decade ago, regular DHEA is a poor mass builder, even if you take tons of it.
The theory was that since it converts to testosterone at a rate of about 1%, you can take enough of it to build muscle – but regular DHEA has several problems that prevent it from being a truly effective anabolic agent, explained briefly below -
Limitations of Standard DHEA
DHEA, less known as 5-DHEA, has several limitations that
prevent it from being a solid mass builder.
Problem #1 – Bioavailability & Absorption.
The bioavailability of DHEA is only about 2-3% (1) – and we fixed that problem with Liqua-Vade HTC — but there were still two major issues preventing DHEA from being an effective muscle builder.
Problem #2 – Calorie Burn Off.
The double bond in the 5th position makes the molecule very thermogenic with a tendency to increase the metabolism to burn off calories by heat generation by conversion to 7-oxo-DHEA. (2) This thermogenic effect makes the metabolism inefficient for muscle building because it burns calories off as heat rather than partitioning them towards muscle.
This effect would make DHEA a great recomposition agent, but a poor size or strength builder.
Problem #3 – Limited Anabolic Potency.
The double bond in the 5th position of regular DHEA also limits its anabolic potential. The main metabolite of DHEA is 5-androstenediol – which is a much weaker androgen than 4-androstenediol. Therefore, by moving the double bond over to the 4th position -
creating 4-DHEA – it becomes an immediate precursor to 4-androstenediol and the anabolic potential is greatly enhanced. (3-4)
It was clear to us that small modifications could be made to the DHEA molecule that would have big improvements on its biological effects – yet keeping its basic "DHEA" structure for legality purposes. The entire AndroSeries would be based around specifically chosen DHEA derivatives delivered in our latest generation of Liqua-Vade HTC – The result of which would blow away our previous generation of steroidal products.
After thousands of hours of focused R&D, I was ready to present the formula to the board of directors.
Making the pitch – Against all odds
The board meeting wasn't so much for approval as it was for moral support. I made the pitch to the board. Then the shots came…
"You understand these products will be too expensive right?"
"We can offer a payment plan. Besides, plenty of guys already pay over several hundred dollars a month for injectable gear or TRT prescriptions, and this will be more convenient and cost effective." I replied.
"You understand the FDA or DEA will come after us once they hear the word ‘steroid' right?"
"The ingredients are DSHEA compliant and the word ‘steroid' is not illegal. We will have our position papers ready" I replied.
"You understand that if this product actually works big pharma is going to crush you right?"
"We will have an attorney armed and ready. If they try to bully us we will fight back." I replied.
"You understand that our credit is exhausted and it would take over 2 years to raise the funds to produce these products right?"
"Yes, that is why we will run a massive discontinuation sale on all current pro-hormone products to raise the capitol." I replied.
On Sept 12th 2010 we launched the Pro-hormone discontinuation sale. It created the biggest uproar Primordial Performance had ever seen. Accusations and rumors flew – "PP is selling out!", "It's a hostile takeover!", "They've been busted by the feds!", and "they are bluffing!" – none of it was true.
One thing was clear, this was going to be the most revolutionary thing Primordial Performance would ever do. This was the beginning of the AndroSeries.
Actually a bit over 3.5yrs, pretty much non-stop, my own version of keto. Built in carb-ups (all-carb meal style) and scheduled cheat days.
You get used to it..and I stayed lean as hell. :yup: