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Smart drugs.

bioman said:
THAT is exactly the stack I use . when running Ani. Taking a break from it currently and noticing the difference.
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Great minds think alike brotha. That's the thing many nootropic junkies don't realize when stacking cholinergics, Alcar, Huperzine, DMAE, etc.... Don't forget about DOPAMINE!!
 
Take 750 ani and 300mg of alpha GPC 2x a day.

Ani is a noot that has dimishing returns and an extra dose can really wreak havoc. It makes me and others I have on it now get a little disorientation, brain fog, and lazy. It is a very powerful noot and you need to stay in recommended levels- which is 750mg 2x a day, with food.
 
drseuss6969 said:
so you recommend alpha-gpc 300mg and 750 mg ani 3 times a day or that as a daily dose divided into 3 doses?
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Depends on your time span of needing it to be active. For me, Aniracetam lasts 2-3 hours. So for a full work day for example I'd take 3 separate doses. Keep in mind that you're increasing glutamate a ton with nootropics like Aniracetam, so avoiding glutamate toxicity by using Methylcobalamin, P-5-P, PQQ, Taurine, Resversatrol, etc will be a big benefit.
 
freqfly said:
The fat content plus DHA in fish oil blends increases the density of Dopamine D2 receptors which is one of the sites Aniracetam exerts its effects on.
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does this apply to all racetams or no? Like noopept or dimiurge
 
This is not a Plug

but we ( ergogenix) carry L-Carnitine L- tartrate. I have bottles of this everywhere and take it for overall health. I know many and most like alcar with their noots

how about LCLT ?>
 
Outside Backer said:
does this apply to all racetams or no? Like noopept or dimiurge
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As far as I know, Aniracetam is unique in it's ability to stimulate Dopamine and Serotonin release.

[h=1]Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP.[/h]http://www.ncbi.nlm.nih.gov/pubmed/11597608

[h=1]Cholinergic and dopaminergic mechanisms involved in the recovery of circadian anticipation by aniracetam in aged rats.[/h]http://www.ncbi.nlm.nih.gov/pubmed/11900768

[h=1]Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.[/h]http://www.ncbi.nlm.nih.gov/pubmed/11412837
 
Outside Backer said:
why wouldnt it be a serious question? Mr Cooper is a huge fan of alcar with his noots and studying,LCLT elicit the same affects?
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i see
well backer, for as long as you been around, and with a company that sells lclt, i am just a lil surprised you don't know the difference between the various forms of carnitine, and their applications, is all

simply put: no, lclt does not elicit same effects as alcar
nor does lclt elicit same effects as other various forms of carnitine

here's a quick rundown:

•Acetyl-L-Carnitine- the acetyl group basically means a collection of acetyl acid. To put it simply the addition of it to the carnitine aids in good memory function and mental focus. As with other forms of L-carnitine it also increases energy
•L-Carnitine-L-Tartrate- tartrate, found in nature in some fruits, helps stabilize the L-carnitine. It’s also and effective antioxidant and some studies have shown it aids in more rapid muscle recovery after heavy stress
•L-Carnitine fumarate- especially good for both metabolizing fat and sending plenty of oxygen to the heart, both valuable properties for athletes
•D-Carnitine, D-L-Carnitine- only available synthetically and the FDA labels it as an illegal food additive
•Glycine Propionyl-L-Carnitine (GPLC) – especially good for muscles as it promotes strong blood flow to them and makes up for oxygen lost during workout. Enhances fat metabolism and waste removal from cells

interesting beast, carnitine is :)
 
snagencyV2.0 said:
i see
well backer, for as long as you been around, and with a company that sells lclt, i am just a lil surprised you don't know the difference between the various forms of carnitine, and their applications, is all

simply put: no, lclt does not elicit same effects as alcar
nor does lclt elicit same effects as other various forms of carnitine

here's a quick rundown:

•Acetyl-L-Carnitine- the acetyl group basically means a collection of acetyl acid. To put it simply the addition of it to the carnitine aids in good memory function and mental focus. As with other forms of L-carnitine it also increases energy
•L-Carnitine-L-Tartrate- tartrate, found in nature in some fruits, helps stabilize the L-carnitine. It’s also and effective antioxidant and some studies have shown it aids in more rapid muscle recovery after heavy stress
•L-Carnitine fumarate- especially good for both metabolizing fat and sending plenty of oxygen to the heart, both valuable properties for athletes
•D-Carnitine, D-L-Carnitine- only available synthetically and the FDA labels it as an illegal food additive
•Glycine Propionyl-L-Carnitine (GPLC) – especially good for muscles as it promotes strong blood flow to them and makes up for oxygen lost during workout. Enhances fat metabolism and waste removal from cells

interesting beast, carnitine is :)
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Who wrote those bullets? Oxygen is not "lost" from muscles. No clue what acetyl acid is. Also, fumarate increases cellular ATP via its incorporation into the TCA cycle. This leads to an increase in [ATP] in muscle, and a decrease in [AMP]. The decrease in [AMP] stimulates Acetyl-CoA Carboxylase, leading to an increase in [Malonyl-CoA], and a block of fatty acid transport into the mitochondria for fat oxidation. So LCL-Fumarate actually inhibits b-oxidation.
 
mr.cooper69 said:
Who wrote those bullets? Oxygen is not "lost" from muscles. No clue what acetyl acid is. Also, fumarate increases cellular ATP via its incorporation into the TCA cycle. This leads to an increase in [ATP] in muscle, and a decrease in [AMP]. The decrease in [AMP] stimulates Acetyl-CoA Carboxylase, leading to an increase in [Malonyl-CoA], and a block of fatty acid transport into the mitochondria for fat oxidation. So LCL-Fumarate actually inhibits b-oxidation.
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ha, yeah wasn't the best sourcing, but i thought it looked pretty :D
besides - speed was of the essence, as i needed to remove myself from the front of my computer yesterday, it was quick to find

pointedly tho, it showed the unique function of alcar, and that this form is specifically unique to memory attributes

simply goes to show, bro - always question your sources
always ;)
 
snagencyV2.0 said:
i see
well backer, for as long as you been around, and with a company that sells lclt, i am just a lil surprised you don't know the difference between the various forms of carnitine, and their applications, is all
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sorry bud I've never stated I was versed in nootropics hence why I asked about noots.

This is a new arena for me since im old now ;) The topic is increasing the action of noots which is what I am trying to LEARN about
 
Outside Backer said:
sorry bud I've never stated I was versed in nootropics hence why I asked about noots.

This is a new arena for me since im old now ;) The topic is increasing the action of noots which is what I am trying to LEARN about
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old eh? damn youngster :D

noots have nothing to do with understanding the actions of various forms of carnitine and what they are best suited for, but okay :shrug:

alcar been around for quite some time (i think before the term nootropic was even invented lol), and long been known as the "smart carnitine"

in any event, learn away! is some interesting stuff for sure, lots to learn indeed
 
Nobody has mentioned acid.
 
I honestly think it's cheaper just to go for ADHD stimulant drugs when YOU NEED IT.

All this nootropic studies don't show significant effects.. All they do is "TRY" to mimick the effects of stimulants for ADHD but won't happen..
 
I'm going to begin a course in statistics and data analysis. Any particular compounds that could be of benefit when studying these subjects? I already has some focus xt.
 
would you guys recommend phenylracetam (lgi n-pept ) to an 18 year old ?
some alternatives ?
im currently on huperzine and focus xt
 
so u think that i shouldnt take hup and focus xt as well ??
could you give me a medical explanation ?
sry for my bad english - im from europe
 
Ditto. This may seem like cheesy parental advice, but your brain is still in the process of wiring itself in your teen years (and this is backed by science). The teen brain doesn't have set neurological pathways yet so altering this process may not be good.
 
hell i wouldn't advise half these kids that are using this stuff in hs/college and the like, and the crazy combinations/dosages that are being spewed around like candy..

doesn't stop kids (like my brother, for example) from abusing the likes of adderall for cramming study sessions either

but what do i know? i'm just an old man
 
Agreed. So many unknowns even for adults, but add in the general neurological plasticity of adolescents and it definitely raises an eyebrow. Basically, you're taking the "try it and hope for the best" practice and upping the ante.
 
snagencyV2.0 said:
hell i wouldn't advise half these kids that are using this stuff in hs/college and the like, and the crazy combinations/dosages that are being spewed around like candy..

doesn't stop kids (like my brother, for example) from abusing the likes of adderall for cramming study sessions either

but what do i know? i'm just an old man
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Well, adderall has decent evidence for neurotoxicity. Conversely, most true nootropics are neuroprotective and being researched for the treatment of neurodegeneration.
 
Like the others, I hate coming across as the old man, but it's just experience and research that leads me to think the way I do about a lot of things. That being said, I used to love taking hallucinogens I was 17-22, so that was my noot back then. I absolutely understand the need for enlightenment and expansion.
 
Centro, Picamilion, and Pramiracetam have been treating me particularly well lately.

Centro seems to have all the benefits of dmae, plus some additional brain energy (I get a mild stim like effect) and when I add 200 mg of pica + 150-250 mg of prami I am feeling cool, calm, and motivated. Also seems to prolong the effect of stimulants such as caffeine, dmaa, etc (Don't notice a crash; feel the effect much longer)
 
bobtail said:
NUVIGIL
It's used to treat narcolepsy but is the best. Tell your doc you fall asleep during the day and you need it.
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I take this and yes i agree. Tell the doc you work 3rd shift and need it for " shift work sleep disorder"

Add ephedrine for a more pronounced effect
 
I love when this thread is bumped. major major career altering test coming up feb 21st. Massive studying begins monday
 
Such an interesting topic. All my noot experimentation has been for career growth and it has helped greatly.
 
sina said:
I honestly think it's cheaper just to go for ADHD stimulant drugs when YOU NEED IT.All this nootropic studies don't show significant effects.. All they do is "TRY" to mimick the effects of stimulants for ADHD but won't happen..
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ADHD medications actually reduce cognitive function in those who don't need them, in addition to being both addictive and neurotoxic.
 
mr.cooper69 said:
ADHD medications actually reduce cognitive function in those who don't need them, in addition to being both addictive and neurotoxic.
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wish more ppl understood this
typically (again) it's the kids who "heard" it's the thing to do, and don't have a clue
target for this audience is 17-22yr olds
 
mr.cooper69 said:
ADHD medications actually reduce cognitive function in those who don't need them, in addition to being both addictive and neurotoxic.
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x2

Whenever I hear the line of thinking about ADHD drugs, I just equate it to saying if you want to think better, take amphetamines.
 
kisaj said:
Such an interesting topic. All my noot experimentation has been for career growth and it has helped greatly.
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like wise 2 years ago I made rank in the military that takes on average 13 years to make and I made it at 6, spent months studying and downing containers of focus XT lol
 
I have been using Demiurge for about a week now, I started the first day at 50mg. I always start off low dose and work my way up. I upped it the next day to 100, next day 150,next 200. The effects for me personally were very little, this morning I took my sccop of Focus-XT and then took 200mg of Demi and can really tell a difference between just taking Focus alone. I feel clear headed, calm, and overall better mood. I have tried the Ani/choline and had GREAT results for about month and then that combo seemed to fade as far as effects go, I couldnt tell the difference from taking it or not, not sure why this happened. My Doc, is really into noots and we will start soon on getting me off Prozac and Klonipin and see how that goes. I have become very apathetic and foggy minded in the last couple of years, so I,m ready to try something else....
 
Right on, Ripd. Look into methylfolate, methylcobalamin and p5p if you haven't already. These are now staples for me and keep some of the depression and cloudiness at bay. I'm trying to conserve my supply of Ani and not use it too steadily as I worry about the effects fading. I save it for high stress/high responsibility times. I also worry that Ani will get banned for good. Amazon stopped selling it already.
 
I spoke with a couple of the Ani suppliers that had to stop selling on Amazon and a couple of them are selling their stock and then they are out. Apparently, with this being a prescription noot outside of the USA, Amazon didn't want to be involved with selling it OTC. Needless to say, a big chunk of their business is overseas where it can't be obtained, so stopping this will hurt business a lot. Plus, there seems to be some uncertainty on how racetams are going to be looked at moving forward. It's well recognized that Aniracetam is a powerful noot, and it does seem that it will one of the first to get hit if they do any regulations.

I stocked up on 2 years worth, just in case. Shelf life is until 2015.
 
Good point about the Ani., I will order today and definitely order in bulk.... Has anyone tried the Demiurge and Ani combo, wonder what that would be like ????


kisaj said:
I spoke with a couple of the Ani suppliers that had to stop selling on Amazon and a couple of them are selling their stock and then they are out. Apparently, with this being a prescription noot outside of the USA, Amazon didn't want to be involved with selling it OTC. Needless to say, a big chunk of their business is overseas where it can't be obtained, so stopping this will hurt business a lot. Plus, there seems to be some uncertainty on how racetams are going to be looked at moving forward. It's well recognized that Aniracetam is a powerful noot, and it does seem that it will one of the first to get hit if they do any regulations.

I stocked up on 2 years worth, just in case. Shelf life is until 2015.
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RipdnTxs said:
Good point about the Ani., I will order today and definitely order in bulk.... Has anyone tried the Demiurge and Ani combo, wonder what that would be like ????
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A bit too strong for me. Found it very hard to pin down the proper choline dose to avoid headaches. Potent combo though.
 
I heard demiurge isn't safe or healthy like severe toxic?

But how strong was it and what dose but yes choline is needed
 
i am taking noopept solo for 4 days now and dont notice much to be frank. perhaps i have to add a cholin source to that?
 
Interesting^. Noopept apparently I read wasn't effectively. I would think it's wise to take Nootropics 1 by 1. To see what is potent and what really doesn't work.. I'll try out

~ Demiurge and see what happens apparently 100mg - 200mg ED is the dosage that does the trick...
I also hear Choline isn't really needed..

A friend recommended these.

1. Noopept + Cererbrolysine + Methylene Blue
2. " High Dose Uridine( 100mg TAU, 600mg UMP) and low dose piracetam(200mg) is the best combo Ive ever had. Gaba blockers are also good only in low doses though. "

and Zi Cao ^
 
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