Xel said:Any idea when you'll be getting more? I've have quite a few things I want and would like to only place one order.
Thanks.
CHAPS said:Do you have a link to that R-ala that you spoke of?
custom said:TTA is out of stock.
I want to have bulk K-RALA and caps in soon; we'll see on that. But you guys do know there is an R-ALA from Gerenova now that is better than the K-RALA, so make what you want to of that.
Yeah, how efficient can you get. I thought R-ALA did the job.custom said:It is somewhere on Invalid Link Removed.
Suposedly the K-RALA is like number three on the list of most effective forms of ALAl now. :think:
Catshmat said:PEA (Phenylethylamine) or the stuff in Designer Supplement's Basic Cuts (minus cayenne, caffeine, and hordenine). Capped would be even better. It is one of the neuroransmitters released when one is in love and it has been called the endogenous amphetamine. Found in minute quantities in chocolate. Any chance of CNW offering it?
custom said:I was looking into this over a year ago...
PEA is a liquid in its natural state, and I have been told by more than one chemict that there is in fact no possible way to spray dry it or anything like that. It seriously makes me wonder how companies have it in dry, capped form. I would have to do it in a liquid cap, and the minimums for those are very, very high.
exnihilo said:Generic ATD?
It's already out there, brother. "Inhibit-E" by SNS. Pricing and servings per bottle blow the others away.exnihilo said:Generic ATD?
custom said:The ECDY is proving a bit tougher than I expected. I will not do it unless I can get the best possible material.
judge-mental said:Both sam-e and enzymes needs to be enteric coated so powder is a nono.
Invalid Link RemovedStephania tetrandra
Stephania tetrandra is an herb used in China and Korea to treat various inflammatory conditions, including rheumatoid arthritis, lung silicosis and hypertension.[2,3] Its main anti-inflammatory components have been found to be tetrandrine (Tet) and fangchinoline (Fang).[4] Stephania extracts concentrate these two ingredients so that their combined level represents 10 to 20 percent of the extract. A Stephania preparation has shown significant effect in reducing the neutrophil-induced inflammation in rheumatoid arthritis.[5]
Tet and Fang have been shown to suppress multiple inflammatory cytokines and mediators. Tet powerfully suppressed nuclear factor kappa Beta (NFkB) activation in human T cells (immune cells).[6]
NFkB is a multimodal inflammation factor that promotes production of powerful inflammatory cytokines including IL-1, IL-6, IL-8 and tumor necrosis factor-alpha.[7] Tet effectively reduced conjunctivitis in mice exposed to ragweed pollen, reducing inflammatory cytokines IL-1 beta and IL-5, while also reducing mast cell degranulation (source of histamine).[8]
All of these are part of the cause of allergen-triggered red, itchy, irritated eyes. Tet and Fang powerfully suppressed formation of thromboxane B2 by human platelets, reducing their tendency to form unnecessary clots.[9] Tet and Fang reduced by 90 percent the production of IL-1 and tumor necrosis factor-alpha when human monocytes (white blood cells) were activated by germs.[10]
Tet showed potent inhibitory effect on leukotriene and prostaglandin (PG) generation by human monocytes and neutrophils.[11] Tet did not directly inhibit the cyclooxygenase (COX) enzyme that makes inflammatory PGs, but rather acted like a corticosteroid to inhibit arachidonic acid release from cell membranes, thereby depriving the COX enzyme of the raw material needed to make PGs.[11]
Invalid Link RemovedClick here to read
Anti-hyperglycemic effect of fangchinoline isolated from Stephania tetrandra Radix in streptozotocin-diabetic mice.
Tsutsumi T, Kobayashi S, Liu YY, Kontani H.
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Hokuriku University, Kanagawa-machi, Kanazawa, Japan.
Kampo medicine, Stephania tetrandra Radix (Stephania) in Boi-ogi-to increases the blood insulin level and falls the blood glucose level in streptozotocin (STZ)-diabetic ddY mice. These actions of Stephania are potentiated by Astragalus membranaceus Bunge Radix (Astragali) in Boi-ogi-to (Liu et al., J. Traditional Med., 17, 253-260, 2000). In the present study, actions of bis-benzylisoquinoline alkaloids isolated from Stephania were investigated in the hyperglycemia of STZ-diabetic mice. A main bis-benzylisoquinoline alkaloid, fangchinoline (0.3-3 mg/kg) significantly fell the blood glucose level of the diabetic mice in a dose-dependent manner. The effect of fangchinoline was 3.9-fold greater than that of water extract of Stephania. However, another main compound, tetrandrine (1-100 mg/kg) did not have any effect. The water extract of Astragali did not affect singly but potentiated the anti-hyperglycemic action of fangchinoline (0.3 mg/kg). Out of used compounds (1 mg/kg) isolated from Stephania, fangchinoline, fangchinoline 2'-N-alpha-oxide and 2'-N-norfangchinoline, which are substituted with 7-hydroxy side chain for 7-O-methyl side chain, decreased to near 50% of high blood glucose level. In addition, tetrandrine 2'-N-beta-oxide, tetrandrine 2'-N-alpha-oxide, tetrandrine 2-N-beta-oxide, fangchinoline 2'-N-alpha-oxide, which are added to 2- or 2'-N-oxide side chain, also decreased to near 50% of the high blood glucose level. In conclusion, fangchinoline but not tetrandrine from Stephania shows the anti-hyperglycemic action in the STZ-diabetic mice. The demethylation of 7-O-position and/or addition of 2- or 2'-N-oxide side chain in bis-benzylisoquinoline compounds in Stephania have a role for the induction of the anti-hyperglycemic actions.
PMID: 12612439 [PubMed - indexed for MEDLINE]
custom said:PowerFull will be in next week.
Needle, is that the stuff in Size On?
custom said:PowerFull will be in next week.
Needle, is that the stuff in Size On?