@Par Deus What is your opinion on treatments for Chronoc Constipation/IBS-C? I've tried a few different probiotics, digestive enzymes, bitters etc. Little to no relief.
Found this interesting
Chronic constipation is a prevalent, burdensome gastrointestinal disorder whose aetiology and pathophysiology remains poorly understood and is most likely multifactorial. Differences in the composition of the intestinal microbiota have been demonstrated ...
www.ncbi.nlm.nih.gov
I kinda skipped past thorough researching of IBS-type stuff because I assumed it had been a thing long enough that it was mostly figured out. But, from what i have seen in the research, tangentially, plus reading IBS stuff from people on reddit microbiome forums, I think think that there are groups whose problems are more complicated than just take a probiotic and get more fiber.
I think a lot of there problems are going to start from outside the gut (bi-directional communication between the gut and the body/brain).
But, I just haven't researched it directly and thoroughly enough to know what is going on with the bad/resistant cases.
I assume you get plenty of fiber/prebiotics, in addition to having tried all kinds of things. Have you tried FODMAPS diet (seems like that is more for type D) or VSL#3 (it just has so much more data than anything else, I consider it on a different level like a pharmaceutical intervention).
The bad/resistant cases, Shock Therapy is certainly made for (unless you tried like rifaximin -- it would very likely be stronger, though obviously not having the supporting ingredients -- but, you have probably tried some of them or at least other things that work through similar anti-inflammatory pathways and such.