seems to effect everyone differently.
With me I only got the runs for the first 3-4 days. after that I was fine. no hypo.
My daughter hasn't had any issues. 2 weeks in.
3 guys at the gym taking it.
1- got hypo on 2 pre workout. he takes them with poweraid and sips on it through out his workout and he is good.
1- No problems. he is actually taking 5 a day.
1- Was like me got the runs for a few days when he started and now he is good. he was telling me the other day he has actually started to cut back his insulin, he is diabetic.