And this is one of the main reasons why my BMP is such a badass recomposition product, and why combining it with BRITE yields such incredible results.
There are many other bioactive molecules regulating adipogenic differentiation and adipogenic key transcription factors. For example, ginsenosides, the major active molecules of Panax ginseng, have shown potential anti-obesity and anti-adipogenic effects [175]. Ginsenosides (25–100 µM) significantly reduced lipid accumulation and expression of key adipogenic genes (PPARγ and C/EBPα) [175]. Moreover, it has been shown that ginseng supplementation prevented high-fat diet induced hyperglycemia and obesity in mice [176]. Adipokines, which are secreted from adipose tissues, are important regulators for adipogenesis, insulin sensitivity, and obesity [177,178]. Among those adipokines, adiponectin increases insulin sensitivity, PPARα activity through PPAR coactivator-1α, and SIRT1-AMPK signaling system, resulting in fat oxidation, reduced lipid synthesis and prevention of hepatic steatosis [177,178]. BMPs are the transforming growth factor-β superfamily and are key regulators for adipogenesis [179,180]. In rodent and human adipose stem cells, BMP4 and BMP7 have been shown to promote transition of white adipocytes to brown adipocytes which metabolizes triglycerides to produce heat and increase energy expenditure through the expression of uncoupling protein 1 (UCP1) [179,180]. Thus, these secreted proteins can be potential molecules regulating adipogenesis and obesity in humans and animals.