Driven2lift
Legend
There is a large enough difference? Assuming a 200/24 dose of EC what dose should I run if I used ECA?
EPHEDRINE
- Thread starter 1976pianoman
- Start date
There is a large enough difference? Assuming a 200/24 dose of EC what dose should I run if I used ECA?
jbryand101b
Banned
The aspirin has a purpose in aiding the effectiveness on fat loss of the combo.
Scientifically.
Scientifically.
1976pianoman
Member
That's not a very scientific sounding statement. You need to use bigger words that I don't understand.
FireRescue
Active member
I admit I have not read any research on EC(A) in quite some time, but I am positive I read reasearch at one time that suggested the A offered little to no advantage. Is there conflicting research in this area?
criticalbench
Legend
I believe I read, that only in very obese individuals the mechanism of action of aspirin is important. Could be super duper wrong tho lol
Mike
JudoJosh
Pro Virili Parte
Quick summary
Ephedrine increases the release of noradrenaline. Noradrenaline then binds to the adrenergic receptor. A protein is then split and one half attaches to the activated adrenergic receptor and the other half binds to adenylate cyclase and this becomes activated which results in the production of cAMP and thus the thermogenic cascade. Now what does aspirin contribute? Noradrenaline is inhibited by prostaglandins. So when you take ephedrine you will get an increase in noradrenaline but you wont get an as increased cAMP output because prostaglandin will be inhibiting noradrenaline. Asprin inhibits the peripheral synthesis of prostaglandins so by taking aspirin you create the enviroment to help maximize your results.
Ephedrine increases the release of noradrenaline. Noradrenaline then binds to the adrenergic receptor. A protein is then split and one half attaches to the activated adrenergic receptor and the other half binds to adenylate cyclase and this becomes activated which results in the production of cAMP and thus the thermogenic cascade. Now what does aspirin contribute? Noradrenaline is inhibited by prostaglandins. So when you take ephedrine you will get an increase in noradrenaline but you wont get an as increased cAMP output because prostaglandin will be inhibiting noradrenaline. Asprin inhibits the peripheral synthesis of prostaglandins so by taking aspirin you create the enviroment to help maximize your results.
jbryand101b
Banned
Thanks, I didn't feel like typing all this on my phone.
FireRescue
Active member
I understand the scientific thoery of the asprin, but there are studies that have been done and E, C, and A that show little to know benefit to the A. Does anyone know of a study that has been done that shows a benefit to including the A?
Driven2lift
Legend
I have read that in several places as well, in for an answer.
Alternate question, how far apart from food should this be used
mr.cooper69
Legend
There are tons of studies man. Aspirin is the least beneficial component of the stack, but it's still beneficial.
jbryand101b
Banned
Link to said study/ies
jbryand101b
Banned
Bull shiit, don't buy.
FireRescue
Active member
These are two that I found quickly.
"There was no significant differences between the groups that received aspirin and the groups that did not. We conclude that aspirin does not potentiate the acute thermic effect of ephedrine and caffeine."
Horton TJ, Geissler CA. Post-prandial Thermogenesis with Ephedrine, Caffeine and Aspirin in Lean, Predisposed Obese and Non-obese women. Int J Obes Relat Metab Disorder, 1996 Feb;20(2):91-95.
"it was demonstrated that aspirin does not potentiate the thermogenic response to ephedrine in lean women and only slightly so in obese women. The increase seen in this study represented a 1.2 kcal per hour increase in metabolism for lean women and a 2.4 kcal per hour increase in metabolism in obese women over use of ephedrine alone"
Horton TJ, Geissler CA. Aspirin Potentiates the Effect of Ephedrine on the Thermogenic Response to a Meal in Obese but not Lean Women. Int J Obes, 1991 May;15(5):359-366.
The second study does show a very, very small advantage in the obese test subjects as compared to the lead test subjects. I will admit that I have not read the complete studies. Maybe their methodologies of testing comprimise the validity of their findings?
I should add I am not anit-asprin. I'm just hasing out some of the info I have read that suggest the asprin is of little to no benefit. Apparenly there have been reseach studies that prove otherwise. I guess I will have to search for those now.
jbryand101b
Banned
On the mobile, will read entire study.
Wonder if there are any on athletes?
Wonder if there are any on athletes?
JudoJosh
Pro Virili Parte
I cant pull up any of these texts but from the abstracts
This one had too much aspirin (300mg) and not enough caffeine (100mg). Caffeine antagonizes adenosine and phosphodiesterase and result are best seen when 200mg are combined with ephedrine (Invalid Link Removed)
This one didnt even combine caffeine in. It compares E vs EA which is just silly really. As mentioned above caffeine plays a very important role in ECA.
This one had too much aspirin (300mg) and not enough caffeine (100mg). Caffeine antagonizes adenosine and phosphodiesterase and result are best seen when 200mg are combined with ephedrine (Invalid Link Removed)
This one didnt even combine caffeine in. It compares E vs EA which is just silly really. As mentioned above caffeine plays a very important role in ECA.
fightbackhxc
Well-known member
They aren't never got my order
criticalbench
Legend
Driven2lift
Legend
So what is the recommended dose for aspirin to include? Bit the bullet and ordered kaizen EC in bulk as it was cheaper. 12 bottles ephedrine and enough caffeine pills to make the 200/24 doses with it. No idea how to dose aspirin though, someone help an ECA virgin out?
kbayne
Legend
81mg baby aspirin
JudoJosh
Pro Virili Parte
Driven2lift
Legend
Thank you both. Interested to see how this works out for me as it will be replacing my alphamine doses. Wish I could just use 1.5 scoops alphamine as my caffeine dose in this haha. Giving it 30 days then a much needed stim break
kbayne
Legend
Not recommended and I'm not recommending it, but I've (along as a few others on this board) used Alphamine as my caffeine choice while using ephedrine.
jbryand101b
Banned
What's alphamine? Sounds like a steroid.
jbryand101b
Banned
Jk :smoker:
bigadam73
Member
Iv used alphamine as my caffeine source as well. I was nervous when I did it, but It wasn't that crazy. I just felt a little more jittery and increased body temp . I prefer just sticking to caffeine pills and bronkaid.
HokiePride
Well-known member
Any updates on your results. Very interested in your scheduling as far as EC or ECA to food to diet to lifting&training. Interesting in utilizing this stack as well and wonder what others have experienced in results.
Driven2lift
Legend
Been on the stack only 5 days. Had decided to add it after a 3 week weight loss plateau. As I had never used it before I maintained calories the same to judge it's effects, glad I did because I weighed in 1.5 lbs lighter this week. using it twice a day
ndnguy85
Member
I just finished two weeks of the EC stack using this protocol. I have seen the most progress ever in my cutting phases. I dropped so much money between alphamine (3 tubs), dcp (2 bottles), LX (1) in the last few months. This is cheaper and more effective.
Week 1 - Day 1-3, 25mg E + 200mg C in two doses
The only SE was on Day 8 when I went to 50mg, I got a lil jittery after the 2nd dose. Day 9 was fine.
I want to drop the caffeine because I usually don't react to caffeine at all. So I am not sure if it's doing anything for me. I do feel really drowsy these days during the day. I need to narrow it down to the EC stack or ZMK that I started about the same time.
1. Should I drop caffeine?
2. Any idea for the cause of my drowsiness?
Week 1 - Day 1-3, 25mg E + 200mg C in two doses
Week 1 - Day 4-7, 37.5mg E + 300 C in two doses
Week 2+ - Day 8-14, 50mg E + 400 C in two doses
The only SE was on Day 8 when I went to 50mg, I got a lil jittery after the 2nd dose. Day 9 was fine.
I want to drop the caffeine because I usually don't react to caffeine at all. So I am not sure if it's doing anything for me. I do feel really drowsy these days during the day. I need to narrow it down to the EC stack or ZMK that I started about the same time.
1. Should I drop caffeine?
2. Any idea for the cause of my drowsiness?
good2Badawg
Member
After just a few days at just 25/200 2-3x daily, fat loss is obvious, but it really makes me drained as well. I cant say 100% its this, but almost positive for myself at least.
Ill say this also, as far as app suppression and fat loss, alphamine doesnt match up to EC imo
But, its a trade off. Slower weight loss, greater sense of well being, less muscle loss, and seemingly no sides VS. Rapid fat loss, some muscle loss, zapped appetite, and feeling like crap after about a week and killing stim tolerance
mr.cooper69
Legend
The ZMK is likely causing the drowsiness. Keep the caffeine or use another source, as it strongly boosts the lipolytic ability of ephedrine.