roblasane
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Thoughts or experience ?? Several pre workouts are now touting the benefits. Primarily beetroot juice .
I have 3 oz spinach and 2 oz beets in my pwo meal, seems to help vascularity a bit... would probably be more if I ate moreThoughts or experience ?? Several pre workouts are now touting the benefits. Primarily beetroot juice .
Keeps bp down as well that may help with any headaches ppl would get from StimsHaha Ricky showing off some good research I love powdered vegetables for heart protection! That's what they are good for says the article nice Ricky ?
This is a good and fair assessment. Did you by chance have around 500mg+ of Beet juice? That should also only help , in a minor amount, with endogenous NO synthesis and its added benefits. However not much...study says it quite clearly hehe, not enough for it to be a huge game changer in Resistance Training But as a good Health Benefit addendum to a diet it should be good bro!Keeps bp down as well that may help with any headaches ppl would get from Stims
Boom, boom!DIETARY NITRATES: A NEW WAY OF INCREASING NITRIC OXIDE PRODUCTION
Dietary Nitrates: A New Way of Increasing Nitric Oxide Production
Nothing beats getting a good pump in the gym. Traditionally, bodybuilders have resorted to using nitric oxide (NO) products to enhance NO production. Many bodybuilders know that nitric oxide can be increased via the synthesis of nitric oxide synthase, through the amino acid arginine. What many bodybuilders may not know is that NO can be produced via an alternative pathway without NO synthase.
Diet is a major provider of nitrates in the body. Nitrates can enhance the production of nitric oxide, independent of the arginine-dependent NO synthase pathway.1 In 2004, it was demonstrated that inorganic nitrate from dietary sources could be a major source of circulating nitrite-- which enhances nitric oxide production independent of the arginine-NOS pathway.2
In one experiment, healthy subjects who ingested a dietary nitrate experienced a four-to-fivefold increase in plasma nitrite. It turns out that much of the dietary nitrite from food entering the stomach from saliva survives intact and reaches the systemic circulation. This suggests that inorganic nitrate from food can be a substrate for NO formation in the body. Nevertheless, based on numerous studies, it seems clear that dietary nitrates are indeed bioactive in the body.
Sources of Dietary Nitrates
Incorporating some fruits and vegetables into the diet in place of high protein can help facilitate greater production of nitric oxide production. A diet rich in fruits and vegetables is associated with a lower blood pressure and reduced risk of cardiovascular events. Despite extensive research, the active ingredient(s) responsible for this effect has not been pinpointed, and trials with single nutrients have been largely unsuccessful.
Remarkably, in a recent study of healthy volunteers,3 the blood pressure-lowering effect of dietary nitrate supplementation was similar to what was seen in the healthy control group in the DASH project, a classic vegetable/fruit diet trial4-- indicating that nitrate could be an important and active ingredient of this diet. This means taking a nitrate supplement could be just as effective as eating fruits and vegetables for increasing NO production.
It should be noted that the dosage of nitrate used in the study (0.1 mmol/kg/day) is readily achievable through a diet rich in vegetables. So for those guys who are not eating fruits and vegetables, you may be missing out on getting better pumps in the gym.
Beetroot Juice-- A High Source of Nitrates
In a recent study, Webb and colleagues found that blood pressure decreases if healthy volunteers ingest a natural nitrate source (beetroot juice). Researchers demonstrated that it was the nitrate in the juice that had the effect, and it occurred via the nitrate's chemical reduction to nitrite.5 In the study, 0.5 L of fresh beetroot juice decreased systolic blood pressure as much as 10 mmHg, and blood pressure was still significantly reduced 24 hours later.5 The researchers found that blood pressure was reduced within just one hour of ingesting beetroot juice, with a peak drop occurring three to four hours after ingestion. Some degree of reduction continued to be observed up to 24 hours after ingestion.
Researchers demonstrated that the decrease in blood pressure was due to the chemical formation of nitrite from the dietary nitrate in the juice. The nitrate in the juice is converted in saliva, by bacteria on the tongue, into nitrite. This nitrite-containing saliva is swallowed, and in the acidic environment of the stomach is either converted into nitric oxide or re-enters the circulation as nitrite. The peak time of reduction in blood pressure correlated with the appearance and peak levels of nitrite in the circulation-- an effect that was absent in a second group of volunteers who refrained from swallowing their saliva during, and for three hours following, beetroot ingestion.
A reduction in blood pressure was also demonstrated in 2006, in healthy volunteers, after three days of dietary supplementation with inorganic nitrate.6 In 2007, it was shown that dietary nitrate decreases whole-body oxygen consumption in humans during submaximal exercise.7 This could be due to the vasodilatation of the blood vessel walls, causing less need for oxygen consumption by muscle. The nitrate-nitrite-NO pathway may be viewed as complementary to the classical arginine-NOS pathway. These pathways work partly parallel to each other, but when oxygen availability is reduced and NOS activity is decreased, nitrite reduction to NO becomes more pronounced.
In sum, consuming natural foods high in nitrates may enhance muscle pumps in the gym. Or you could try beetroot juice, which is naturally high in nitrates.
References:
1. Lundberg JO, Weitzberg E, Cole JA and Benjamin N. Nitrate, bacteria and human health. Nat Rev Microbiol, 2004 Jul;2(7):593-602.
2. Lundberg JO and Govoni M. Inorganic nitrate is a possible source for systemic generation of nitric oxide. Free Radic Biol Med, 37, 395-400 (2004).
3. Larsen FJ, Ekblom B, Sahlin K, Lundberg JO and Weitzberg E. Effects of dietary nitrate on blood pressure in healthy volunteers. N Engl J Med, 355, 2792-2793 (2006).
4. Appel LJ, Moore TJ, Obarzanek, E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM,
Cutler JA, Windhauser MM, Lin PH and Karanja N, A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med, 336, 1117-1124 (1997).
5. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, Macallister R, Hobbs AJ and Ahluwalia A. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension, 51, 784-90 (2008).
6. Larsen FJ, Ekblom B, Sahlin K, Lundberg JO and Weitzberg, E. Effects of dietary nitrate on blood pressure in healthy volunteers. N Engl J Med, 355, 2792- 2793 (2006).
7. Larsen FJ, Weitzberg E, Lundberg JO and Ekblom B. Effects of dietary nitrate on oxygen cost during exercise. Acta Physiol (Oxf), 191, 59-66 (2007).
Haha Good one Rob , lets see, I see your Pair of Queens, I'll raise yah Pair of Ace's in the pocket!DIETARY NITRATES: A NEW WAY OF INCREASING NITRIC OXIDE PRODUCTION
Dietary Nitrates: A New Way of Increasing Nitric Oxide Production
Nothing beats getting a good pump in the gym. Traditionally, bodybuilders have resorted to using nitric oxide (NO) products to enhance NO production. Many bodybuilders know that nitric oxide can be increased via the synthesis of nitric oxide synthase, through the amino acid arginine. What many bodybuilders may not know is that NO can be produced via an alternative pathway without NO synthase.
Diet is a major provider of nitrates in the body. Nitrates can enhance the production of nitric oxide, independent of the arginine-dependent NO synthase pathway.1 In 2004, it was demonstrated that inorganic nitrate from dietary sources could be a major source of circulating nitrite— which enhances nitric oxide production independent of the arginine-NOS pathway.2
In one experiment, healthy subjects who ingested a dietary nitrate experienced a four-to-fivefold increase in plasma nitrite. It turns out that much of the dietary nitrite from food entering the stomach from saliva survives intact and reaches the systemic circulation. This suggests that inorganic nitrate from food can be a substrate for NO formation in the body. Nevertheless, based on numerous studies, it seems clear that dietary nitrates are indeed bioactive in the body.
Sources of Dietary Nitrates
Incorporating some fruits and vegetables into the diet in place of high protein can help facilitate greater production of nitric oxide production. A diet rich in fruits and vegetables is associated with a lower blood pressure and reduced risk of cardiovascular events. Despite extensive research, the active ingredient(s) responsible for this effect has not been pinpointed, and trials with single nutrients have been largely unsuccessful.
Remarkably, in a recent study of healthy volunteers,3 the blood pressure-lowering effect of dietary nitrate supplementation was similar to what was seen in the healthy control group in the DASH project, a classic vegetable/fruit diet trial4— indicating that nitrate could be an important and active ingredient of this diet. This means taking a nitrate supplement could be just as effective as eating fruits and vegetables for increasing NO production.
It should be noted that the dosage of nitrate used in the study (0.1 mmol/kg/day) is readily achievable through a diet rich in vegetables. So for those guys who are not eating fruits and vegetables, you may be missing out on getting better pumps in the gym.
Beetroot Juice— A High Source of Nitrates
In a recent study, Webb and colleagues found that blood pressure decreases if healthy volunteers ingest a natural nitrate source (beetroot juice). Researchers demonstrated that it was the nitrate in the juice that had the effect, and it occurred via the nitrate’s chemical reduction to nitrite.5 In the study, 0.5 L of fresh beetroot juice decreased systolic blood pressure as much as 10 mmHg, and blood pressure was still significantly reduced 24 hours later.5 The researchers found that blood pressure was reduced within just one hour of ingesting beetroot juice, with a peak drop occurring three to four hours after ingestion. Some degree of reduction continued to be observed up to 24 hours after ingestion.
Researchers demonstrated that the decrease in blood pressure was due to the chemical formation of nitrite from the dietary nitrate in the juice. The nitrate in the juice is converted in saliva, by bacteria on the tongue, into nitrite. This nitrite-containing saliva is swallowed, and in the acidic environment of the stomach is either converted into nitric oxide or re-enters the circulation as nitrite. The peak time of reduction in blood pressure correlated with the appearance and peak levels of nitrite in the circulation— an effect that was absent in a second group of volunteers who refrained from swallowing their saliva during, and for three hours following, beetroot ingestion.
A reduction in blood pressure was also demonstrated in 2006, in healthy volunteers, after three days of dietary supplementation with inorganic nitrate.6 In 2007, it was shown that dietary nitrate decreases whole-body oxygen consumption in humans during submaximal exercise.7 This could be due to the vasodilatation of the blood vessel walls, causing less need for oxygen consumption by muscle. The nitrate-nitrite-NO pathway may be viewed as complementary to the classical arginine-NOS pathway. These pathways work partly parallel to each other, but when oxygen availability is reduced and NOS activity is decreased, nitrite reduction to NO becomes more pronounced.
In sum, consuming natural foods high in nitrates may enhance muscle pumps in the gym. Or you could try beetroot juice, which is naturally high in nitrates.
References:
1. Lundberg JO, Weitzberg E, Cole JA and Benjamin N. Nitrate, bacteria and human health. Nat Rev Microbiol, 2004 Jul;2(7):593-602.
2. Lundberg JO and Govoni M. Inorganic nitrate is a possible source for systemic generation of nitric oxide. Free Radic Biol Med, 37, 395-400 (2004).
3. Larsen FJ, Ekblom B, Sahlin K, Lundberg JO and Weitzberg E. Effects of dietary nitrate on blood pressure in healthy volunteers. N Engl J Med, 355, 2792-2793 (2006).
4. Appel LJ, Moore TJ, Obarzanek, E, Vollmer WM, Svetkey LP, Sacks FM, Bray GA, Vogt TM,
Cutler JA, Windhauser MM, Lin PH and Karanja N, A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med, 336, 1117-1124 (1997).
5. Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, Macallister R, Hobbs AJ and Ahluwalia A. Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. Hypertension, 51, 784-90 (2008).
6. Larsen FJ, Ekblom B, Sahlin K, Lundberg JO and Weitzberg, E. Effects of dietary nitrate on blood pressure in healthy volunteers. N Engl J Med, 355, 2792- 2793 (2006).
7. Larsen FJ, Weitzberg E, Lundberg JO and Ekblom B. Effects of dietary nitrate on oxygen cost during exercise. Acta Physiol (Oxf), 191, 59-66 (2007).
http://jap.physiology.org/content/111/2/619.fullWe wish to stress that, unlike other research groups that have used sodium nitrate to investigate the physiological role of the nitrate-nitrite-nitric oxide (NO) pathway both at rest and during exercise (e.g., 7–10), in all of our recent studies we have used a nitrate-rich vegetable (beetroot) juice product to elevate plasma [nitrite] and potentially increase NO bioavailability (1, 2, 6, 13). We agree with Lundberg et al. that “with natural sources of nitrate such as whole vegetables or vegetable juices, we do not foresee any acute risks.” Indeed, we deliberately chose this “natural” supplementation regimen because of strict regulation of nitrate salts in the UK and the possible health risks associated with consuming them. As we pointed out previously (3), nitrate-rich whole vegetables or vegetable juices also contain antioxidants and polyphenols that may act to limit the formation of potentially harmful nitrogenous compounds. We agree with others (4, 11, 14) that the health benefits of increased fruit and vegetable consumption may be consequent, at least in part, to a commensurate increase in nitrate intake.
In summary, we have not advocated the uncontrolled use of nitrate or nitrite salts by athletic or other human populations in articles published in this journal (1, 2, 6) or elsewhere (14), and nor would we do so. Lundberg et al. are right to draw readers' attention to the potential hazards of this practice. Dietary supplementation with nitrate-rich vegetable products, however, appears to afford several possible benefits to human health and performance, including, but not limited to, a reduction in resting blood pressure, and lowering of the whole body O2 cost of physical activity
So are you saying that using it will not modify the amount of NO in the system Vaungh?testing for nitrate content in ANY product that uses beet root extract would be comical. You're looking at .5-1.5% total nitrates by weight.
Because they are healthy ! And pop-eye likes Spinach !I knew i ate spinach and beets for a reason. Wasnt sure why other than mom told me..
So are you saying that using it will not modify the amount of NO in the system Vaungh?
I concur with this post haha, I had researched a fair bit myself about this, but I thought you would have a more solid and respectful answer than mine. Thanks for telling us that 400-500mg are not enough for it, meaning...a yield of what...5-8mg? Awesome NO for massive pumps huh?Nitrates will modify the amoutn of NO in your system, however getting enough nitrates from food or food extracts is currently impossible. I have searched high and wide for nitrate rich extracts, but the highest I have EVER seen was just below 3%...which means youd need dozens upon dozens of grams of material to get a small nitrate dose.
exactly ...right now the only way to get legit doses of nitrates are in nitrate containing products. I believe that products like HemaVol provide equal or greater NO boosting, but through separate pathways. I'd love to be able to get a beet root extract that 20-40% nitrates, would make it possible for everyone to include nitrates in damn near every formula.I concur with this post haha, I had researched a fair bit myself about this, but I thought you would have a more solid and respectful answer than mine. Thanks for telling us that 400-500mg are not enough for it, meaning...a yield of what...5-8mg? Awesome NO for massive pumps huh?
I do agree, Hemavol contains Agmatine Sulfate , which is awesome for improving NO values due to Endogenous production and synthesis optimization. Real Pump product right there Vaungh! .exactly ...right now the only way to get legit doses of nitrates are in nitrate containing products. I believe that products like HemaVol provide equal or greater NO boosting, but through separate pathways. I'd love to be able to get a beet root extract that 20-40% nitrates, would make it possible for everyone to include nitrates in damn near every formula.
Heyyy what am I chop liver???? Lol and nice find robBoom, boom!
Great post repped!
Hemavol didnt do crap for me.. dosed 3 scoops at a time and i just threw half of the tub out.I do agree, Hemavol contains Agmatine Sulfate , which is awesome for improving NO values due to Endogenous production and synthesis optimization. Real Pump product right there Vaungh! .
Maybe the new supplement you just got sponsored for will yield more results for you empirically speaking? (Which in the end its best, we are meant to use what works for US and not for anyone else)Hemavol didnt do crap for me.. dosed 3 scoops at a time and i just threw half of the tub out.
Nail on the head here Vaughn.exactly ...right now the only way to get legit doses of nitrates are in nitrate containing products. I believe that products like HemaVol provide equal or greater NO boosting, but through separate pathways. I'd love to be able to get a beet root extract that 20-40% nitrates, would make it possible for everyone to include nitrates in damn near every formula.
Never, you're very intelligent!!Heyyy what am I chop liver???? Lol and nice find rob
How did you dose it? empty or full stomach? how much water?Hemavol didnt do crap for me.. dosed 3 scoops at a time and i just threw half of the tub out.
Welcome!LOL @ the nitrate-abuse "studies"
Same thoughts its fun , but what do you think of a concentration of 1 to 1.5% of around 450-500mg of Beets? Is .05g enough to matter? No right? It is a perfectly safe supplement with no added benefits right?LOL @ the nitrate-abuse "studies"
Same thoughts its fun , but what do you think of a concentration of 1 to 1.5% of around 450-500mg of Beets? Is .05g enough to matter? No right? It is a perfectly safe supplement with no added benefits right?
I <3 Cybear , thanks to you I spend more time reading researches on stuff that isn't even related to my Degree!! Jesus...If I have a "Change of Habits" its on you bro!Correct, that is a worthless dose of nitrates, naturally occurring or otherwise.
What is the nitrate standardization of nitratene? Oh, and I'd never ever use more than 1 scoop. Caffeine, TMG, and BA (for carnosine maintenance) are all full-dosed at 1 scoop anyway.Caffeine: 400mg
Nitratene: 960mg
Beta Alanine: 4g
Betaine Anhydrous: 5g
Two scoops of ConDense, users can split the dose in half if it is too "strong for them".
Thanks brother. I'm awaiting more info on it, the owner has a patent on it. It's a big email file I got and haven't taken a look yet.What is the nitrate standardization of nitratene? Oh, and I'd never ever use more than 1 scoop. Caffeine, TMG, and BA (for carnosine maintenance) are all full-dosed at 1 scoop anyway.
Hey Vaungh is .0048 to .014 grams enough to have an impact on Hypertrophy or Sacroplasmic geared workouts? Just wondering, I was thinking of adding it, but since I am already using Citrulline Malate and Agmatine Sulfate I was wondering if it was pointless?testing for nitrate content in ANY product that uses beet root extract would be comical. You're looking at .5-1.5% total nitrates by weight.
D-pol says nitratene is 73% nitrates. If this is true then 1 scoop is perfect. I'd actually go so far as to say that 2 would be dangerous and essentially embodies what the study on the previous page of this thread forewarns against.Thanks brother. I'm awaiting more info on it, the owner has a patent on it. It's a big email file I got and haven't taken a look yet.
No, you want a couple hundred milligrams minimumHey Vaungh is .0048 to .014 grams enough to have an impact on Hypertrophy or Sacroplasmic geared workouts? Just wondering, I was thinking of adding it, but since I am already using Citrulline Malate and Agmatine Sulfate I was wondering if it was pointless?
Right 1 scoop is where users should start, 2 could be the max!!!!D-pol says nitratene is 73% nitrates. If this is true then 1 scoop is perfect. I'd actually go so far as to say that 2 would be dangerous and essentially embodies what the study on the previous page of this thread forewarns against.
That's weird I could've swore the standarization max found for Beets is .5 to 1.5% , gotta read up a bit bro I'll get back to you on this one. However I don't think Vaungh is wrong with the numbers he came out with !No, you want a couple hundred milligrams minimum
Coop, had to extract this from your PM; damn good coming from you.Lol thanks...if the new product is standardized to 73% nitrates it's one of the best stimmed preworkouts out there
Word. I'm see if I can get ya a tub if you are interested in trying it?^ Heh, well it's true. The stimmed preworkout category is so laughably weak. SAN Fierce Domination, Cytosport Monsterpump...not much else out there in terms of full-dosed ingredients. All the stars are in the stim-free preworkout category, for which I simply throw a tab of caffeine and bronkaid into the mix and enjoy
Haha I remember sending you a link to Fierce Domination and thinking you were gonna like it and maybe (i know far guess) not know about it and you said: "Agree great formula" . So...talking this supp , since you said stim PWO are laughably weak...and only mentioned 2 good I guess your seal is on its pocket !^ Heh, well it's true. The stimmed preworkout category is so laughably weak. SAN Fierce Domination, Cytosport Monsterpump...not much else out there in terms of full-dosed ingredients. All the stars are in the stim-free preworkout category, for which I simply throw a tab of caffeine and bronkaid into the mix and enjoy
First, check if nitratene is 73% nitrates as per D-pol's label (is nitratene beet root? haven't looked much into patent names). If it is, I'm down to try a sample (I'm not gonna milk you for a tub lol).Word. I'm see if I can get ya a tub if you are interested in trying it?
Got cha, let me invite Grambo in he can clarify this... We will finish this up later. I'd like to hear your review on it.First, check if nitratene is 73% nitrates as per D-pol's label (is nitratene beet root? haven't looked much into patent names). If it is, I'm down to try a sample (I'm not gonna milk you for a tub lol).
First, check if nitratene is 73% nitrates as per D-pol's label (is nitratene beet root? haven't looked much into patent names). If it is, I'm down to try a sample (I'm not gonna milk you for a tub lol).
That's from the write up if I am not mistaken ! How did we get here...Rob , howwe and I were having some fun talking about Veggies :/Nitratene™
Inorganic nitrate found in beets, spinach, etc…proliferates nitric oxide through a novel biological pathway, nitrate→nitrite→nitric oxide, converted through entero-salivary circulation as opposed to the more traditionally known arginine→NO synthase→nitric oxide pathway. Although nitrate, as related to exercise performance, is still in its infancy, the results on performance parameters are nothing short of salivary (pun intended)!
Nitrate has been shown to be a powerful aerobic and anaerobic ergogenic aid by reducing the oxygen cost of exercise, translating into lower perceived exertion and/or a greater maximal workload capacity. Astonishingly, the increased work comes without an accompanying increase in blood-lactate, meaning your muscles actually become more energetically efficient. This increase in mitochondrial efficiency (P/O ratio) is due to the reduced cost of ATP (muscular currency) to produce muscular force.
See Rob good choice in ConDense there brother, sure you will enjoy!Can we rename this thread "The nitrate chronicles "?
Can't wait ;-) on my off day Ima take some before I get naughty with the wife... 100% GUARANTEED!!!!!See Rob good choice in ConDense there brother, sure you will enjoy!
Glad you'll be logging it brother.
:thumbsup: