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  1. @DR.D ... why accutane is so bad ?

    Hey DR.D, I thought you'd be capable of answering my question, I know isotretinoin is very effective for treating acne but also got a very bad safety profile, why is that ? I do know it's a retinoid but I've read in the pharmacology profile that it's mechanisms of action are unknown, except that...
  2. my PGF2a experience ... bad

    okay I thought it would be interesting to share my experience with PGF2a. I've started it three days ago now with AAS (propionate, NPP), my dosages were 1.5mg in each muscle 4 times a day ; okay so for the first shot in the next five minutes I felt sore in my deltoids but it was bearable, I then...
  3. my little stack for winter

    ok bros here we go, from left to right : (and sorry for the shitty quality pic, it was taken with my cell phone) 425x proviron 25mg tabs (white bottle) 2x 50ml lutalyse mg/ml (PGF2a) 7x biogonadyl kits (5x 500 IU amps per box) 4x eurochem boldenon 200mg 8x greather pharma boldenone 100mg 14x...
  4. HCG refrigerated ?

    i've just received my HCG packets, the HCG is in powder form, so I'm not sure if I have to keep it in the fridge or not,
  5. how much letro

    I really want to keep bloat to a MINIMUM with my next cycle, I'll be on 800mg of prop I thought about 0.75mg EOD should I bump to 1mg ? thx
  6. (ketotifen) TNF-a and muscle wasting, a direct effect..

    I thought this was very interesting...and further support the utility of ketotifen... --------- Abstract : Tumor necrosis factor-α (TNF-α) is a polypeptide cytokine that has been associated with muscle wasting and weakness in inflammatory disease. Despite its potential importance in muscle...
  7. halo only PWO

    I was wondering if it really worth it for strength and androgenic induced "intensity" on the weights, to use halo let's say at 10mg PWO or 10mg in the morning and 10mg pre w/o 4 days a week... (hepatoxicity wise) ...
  8. slin not so powerful ?

    "From the very onset let me say that I cannot in good conscience recommend that a body builder use insulin. This trend started a few years ago when some prominent people touted insulin as the mother of all anabolic hormones. Certainly if this were the case, type-II diabetics using huge amounts...
  9. oratropin and heart hypertrophy @IBE

    after all the research and studies I've read on the role of the GH / IGF-1 axis on the cardiac myocytes, that GH and IGF1 are critical in the regulation of cardiomyocyte growth, I was wondering, LR3 IGF-1 (non mediated) should in theory provoke enlargment of the heart right ? But what about OT ...
  10. ingredients of powerfull ? @USPlabs

    I'm very curious about the " saponins " extract, what is that ?? I know muira puama is an herb used as an aphrodisiac, but I really have no idea what the 100% saponins extract are about ... tribulus terrestris can also be standardized to saponins, and based on the definition of the term saponins...
  11. mega dosing x factor .... anyone ?

    Hey, I plan to run 1g (4 caps ED) of x factor but the studies I've came across says that they have used 1.5g ED, moreover I'd like to know if there would be any linear response of the production of PGs in muscle with doses increasing.... @Aeternitatis and others..
  12. my 5 month 2006 cycle... take a look

    ok here we go bros my main question is should I add slin (humalog) between the IGF it's in excel format and I zipped it as you can't post excel files...
  13. somatokine

    interesting.... ------------ When IGF-I is bound to binding protein-3 (BP3), as it is in nature, it does not display these acute limitations. Furthermore, BP3 appears to be critical in the regulation of the release of IGF-I to target tissue sites, where the hormone is active only when needed...
  14. @derek, low dose sesamin while bulking ?

    I was planning to add 500mg of sesamin on my next cycle to have the repartitionning effects of it, I'll be also running T3 at 15mcg, do you think I could increase the sesamin to 1000mg to get even greater repartitionning effects or would it compete with the thyro receptor ? I'm fluctuating...
  15. found something funny on spotinjections

    this looks to me like a 22g, 1.2' ?! Ouch ! and it also seems like he's shooting at least 3cc .... anyone here has done or do that with that type of size ? bottom line, do not always follow the instructions on spotinjections.... :jaw:
  16. cissus with AAS ?

    I was wondering if I could see any benefits concerning joint and ligaments health to take cissus RX while being on cycle, maybe before bed will be even better for the anti catabolic effect of cissus to be effective while sleeping ? bump
  17. @aeternitatis : confused about AA acid

    I came across this : "As eluded to above, insulin stimulated protein synthesis is linked to the production of phospholipases which lead to increased availability of arachidonic acid. This is a two edged sword. Increased availability of arachidonic acid can increase the amount of PGF2a thereby...
  18. deca @ 800mg EW and bloat

    i'm considering running deca at 800mg for my next cycle and I was wondering how much the bloat problem would be if running an AI like aromasin throughout ? thx bros
  19. ronnie's new video preview

    it seems like he's getting betetr and better over the years :think:, he looks insane http://www.bigroncoleman.com/Pages/home.html (go on click here for a preview)
  20. masteron used to control estro ?

    I'll be on 1g of test / week and I've read that masteron got is kinda strong at blocking aromatase activity because of it's DHT derived structure, although it cannot compare to AIs, I think it's potency is more in the range of proviron, maybe more, but I was wondering if running it at 400mg /...
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