The Role of PPAR's in Cancer
A bit of educational information on PPAR's and cancer. There has been
A LOT of concern from many researchers regarding the role of PPAR's in cancer. Many of the PPAR's tested in mice lead to cancerous tumors in testing. This includes cardarine, or should I say cardarine was the PPAR research product that really brought this concern to light for researchers.
I decided to do a little research there and found this article recently that said although the PPAR agonist caused cancer in mice that they do not seem to cause the same problem in humans. It explained the process at which they found this out and why it is that way. Has to do with how the liver processes it. The liver of the mice is unable to handle it due to a higher sensitivity level or something along those lines. Either way it alleviates my concerns on the studies that reported PPAR's causing cancer in mice.
It is here if you would like to read it.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435221/