The typical recommendation for products like this is for companies to suggest 8 to 12 weeks on followed by a break. That is really more of suggesting on the side of caution than because of any actual researched need to do so though. Since that is the recommendation, that is what I would have to suggest but I've seen many people use it year round and I do myself but I have an actual endocrinology condition and M-Test helped improve some of my levels to where my doctor told me to stay on it myself so my situation is a bit unique.