Well, for me the creatine was a bit high and personally my body did not like it. I was told it was because i was using a supplement company version which most are crap instead of something from a vitamin company but I never did go to buy it. Spurfy prefers and swears by NOW brand creatine. I was using Dymatize. I did notice a lot more size and synergy in the beginning with the really high creatine but then it got to where I was not very hungry and was getting a bit constipated.
I did notice that some of the things like appetite suppression seemed less on the night time only dose of Var. Also it seemed I didn't experience a lot of the other sides, or I only experienced them while sleeping one of the 2.
I did seem to have better energy levels when fasting in the AM though due to having a high level of ATP available from the creatine.
Hyde also had or is still on his run doing it like this. I think he limited the creatine as well though. So we might need someone with an iron gut, or who is using NOW creatine to get the full read on this. I will order some Now Creatine when or if I run Var again to see if I have an even better experience.
Either way though I found the evening dose method to be a good one for me. Like I mentioned before I seem to have slept through some of the sides. I ran the SD the same way and handled it MUCH better than before. I know my BP went up from the dose but I slept through most of that feeling. I know I got a stomach bug in the middle but it was not related to the SD. So I will more than likely use late afternoon or evening doses for most orals. It just seemed more manageable.