Epicatechin

I'm Caucasian with a little white dick. The bitch wants it, she can get it. Now let's stop being butt hurt, and move on.
 
It was a joke. I appreciate the positivity you're bringing to the thread though.....
 
ucheoma said:
Yeah. That old tired explanation...dont be so sensitive it was only a joke. Could have made up any joke. Just had to pick one which laughs at another race. Im on this site for bodybuilding/supplement talk. Not stupid, racist jokes. I dont think Asian members find it a tiny bit funny and its a tasteless joke at best
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Actually, I showed it to my Asian friend and he busted out laughing. Guess what: people say the same thing about Irish people and that we are all drunks. I don't get butt hurt over it because I am not soft as baby thigh like you and have a sense of humor about things.

You are everything that is wrong with the world today. Everyone gets
So offended about every little thing. Either grow some thicker skin or develope a sense of humor. I completely against racism but getting offended over something like that is ridiculous. My nephew got in trouble for calling sitting cross legged "Indian style" political correctness has gone way too far.

Cheers 3-ply. Now back to the discussion of supplements
 
amen
 
Danes said:
Dont force me to slam my dick in the table! Thats how earthquakes are made!!!

:D
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LOL. This thread just got even better. Epicatechin threads (not just the compound) never fail to make someone very angry. Epirage might be a new thing.
 
On another note, good to see CEL back. Thought they were done and just selling through remaining stock of cycle assist.

I'd like to see some new transdermals and stuff
 
AndrewMcD said:
Yeah god forbid the opinions of people on an online forum are negative about me...oh wait. That literally does not matter whatsoever.
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It ain't the size of your pencil, it's how you write your name
 
CATdiesel76 said:
On another note, good to see CEL back. Thought they were done and just selling through remaining stock of cycle assist.

I'd like to see some new transdermals and stuff
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You and me both :) looks like a brand revival...
 
ma70 said:
LOL. This thread just got even better. Epicatechin threads (not just the compound) never fail to make someone very angry. Epirage might be a new thing.
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Lol!
EpiRage sounds good.
Epicatechin with proviron ;)
 
Here is a little teaser about Olympus Labs new and improved Ep1c Unleashed!!

Invalid Link Removed
 
"Olympus Labs ...are confidently saying the new supplement “will alleviate the bioavailability issues of epicatechin” Hmmm


Danes was completely on point.
 
ucheoma said:
"Olympus Labs ...are confidently saying the new supplement “will alleviate the bioavailability issues of epicatechin” Hmmm


Danes was completely on point.
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Not only saying but we will be showing and unfolding what this new product is capable of starting as early as this week.
 
ucheoma said:
"Olympus Labs ...are confidently saying the new supplement “will alleviate the bioavailability issues of epicatechin” Hmmm


Danes was completely on point.
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Absorption is no issue with Epicatechin but bioavaiability need a boost. Simple as Ascorbic acid could do a job. Not to mention grape fruit extract etc
 
Olympus Labs said:
Not only saying but we will be showing and unfolding what this new product is capable of starting as early as this week.
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I see it as a big positive that a company continually strives for improvement in the effectiveness and quality of its products... I shall look out for this, and the science behind it
 
Danes said:
Absorption is no issue with Epicatechin but bioavaiability need a boost. Simple as Ascorbic acid could do a job. Not to mention grape fruit extract etc
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How much of ascorbic acid would you need? Is there enough in a multivit (orange triad) and if so would it be more cost effective to 'stack' with version 1.0 EPis which are likely to come down in price?

Also do you still think TD is the most effective delivery mechanism for increasing bioavailability? I don't believe the new OL EPI will be a TD but correct me if I'm wrong.

OL- when the new EPIC is unleashed I'd love to learn how much more EPI will be bioavailable versus the current product
 
ucheoma said:
How much of ascorbic acid would you need? Is there enough in a multivit (orange triad) and if so would it be more cost effective to 'stack' with version 1.0 EPis which are likely to come down in price?

Also do you still think TD is the most effective delivery mechanism for increasing bioavailability? I don't believe the new OL EPI will be a TD but correct me if I'm wrong.

OL- when the new EPIC is unleashed I'd love to learn how much more EPI will be bioavailable versus the current product
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Ep1c unleashed will be available in both TD and oral.. :fing02:
 
ucheoma said:
How much of ascorbic acid would you need? Is there enough in a multivit (orange triad) and if so would it be more cost effective to 'stack' with version 1.0 EPis which are likely to come down in price?

Also do you still think TD is the most effective delivery mechanism for increasing bioavailability? I don't believe the new OL EPI will be a TD but correct me if I'm wrong.

OL- when the new EPIC is unleashed I'd love to learn how much more EPI will be bioavailable versus the current product
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500mg og Ascorbic A Would be enough but would not hurt more actually.
Using OG Ep1c with such as grape fruit extract or simple as ascorbic acid would make it better.
But I believe new Ep1c will contain everything you need to take Epicatechin to a new level :)

Personaly, I really see no point making TD version of EPI. That will actually not be any better.
 
I love epicathecin products. So I'm excited to try this out! I knw how it works on me so I'll knw for sure how much more effective it is compared to the original standalone formula
 
Danes said:
500mg og Ascorbic A Would be enough but would not hurt more actually.
Using OG Ep1c with such as grape fruit extract or simple as ascorbic acid would make it better.
But I believe new Ep1c will contain everything you need to take Epicatechin to a new level :)

Personaly, I really see no point making TD version of EPI. That will actually not be any better.
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whats your thoughts on an 8 hours release via TD vs much faster oral?
 
NoAddedHmones said:
whats your thoughts on an 8 hours release via TD vs much faster oral?
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If I would choose, I would deff choose thr 8 hours release. But I need to admit, we have no proof from a TD epicatechin product. Will it have 8 hour release? Do it work like that?

A study done on oral Epi,it showed that taking each 4th-5th hour would make it more stable. So timing and bioavaiability supporters would deff play a huge role to an EPI product.

I will deff try OL and CEL versions
Ofcourse in higher doses, adding own bio-a. Supporters if they lack in the products.
I hope I will get pumps and better endurance/work capacity of it
 
Danes said:
500mg og Ascorbic A Would be enough but would not hurt more actually. Using OG Ep1c with such as grape fruit extract or simple as ascorbic acid would make it better. But I believe new Ep1c will contain everything you need to take Epicatechin to a new level :) Personaly, I really see no point making TD version of EPI. That will actually not be any better.
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The pharmacokinetics of epicatechin have been fairly well studied. There appears to be two major obstacles of bioavailability which are pretty much the same as most flavonoid compounds; limited intestinal transport and extensive presystemic metabolism. Although components grape fruit juice can inhibit the intestinal efflux transporter of epicatechin- it does not appear to have significant bearing on bioavailability. Presystemic metabolism appears to be chiefly mediated by sulfotransferase (1A1) in humans which is largely expressed in the liver. So theoretically co-administration of a compound with greater affinity for this enzyme should result higher concentration reaching the blood. I know of a few compounds that have high affinity for this enzyme at low concentrations- however they have not been specifically tested on the metabolism of flavonoids.
 
furion said:
The pharmacokinetics of epicatechin have been fairly well studied. There appears to be two major obstacles of bioavailability which are pretty much the same as most flavonoid compounds; limited intestinal transport and extensive presystemic metabolism. Although components grape fruit juice can inhibit the intestinal efflux transporter of epicatechin- it does not appear to have significant bearing on bioavailability. Presystemic metabolism appears to be chiefly mediated by sulfotransferase (1A1) in humans which is largely expressed in the liver. So theoretically co-administration of a compound with greater affinity for this enzyme should result higher concentration reaching the blood. I know of a few compounds that have high affinity for this enzyme at low concentrations- however they have not been specifically tested on the metabolism of flavonoids.
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GSE ,C-Vitamin and xylitol are just one of few that can enhance the delivery and bioavailability of catechins.(Effective on intestinal cell transport, implying the inhibition of the efflux transport mechanism).
 
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