In regards to the above. Sorry for the delayed reply addressing these points.
For Euonymus, we used an aqueous bark extract, at 20:1 concentration. (High in polysacharrides and triterpene/steroidal glycosides.) This is exactly consistent with the extract used in the only study which examined the effects of Euonymus Alatus on aromatase. For Urtica, we used a full-spectrum aqueous root extract. We can't claim 98% standardization to 3,4-divanillyltetrahydrofuran - but, as we've all learned, most of those companies who have claimed to have a 98% extract were sorely mistaken. The extract we use in Paragon comes from a reputable source, seems to be highly effective, and is dosed properly.
As far as Vitamin K is concerned, we believe that it should have an effect, as long as the dose is high enough. The mechanisms of action are intriguing, particularly its effects on P450scc expression, and this may synergize well with the rest of the formula. It seems to work dramatically well in animal experiments, and the doses we use have been shown to be safe in humans. There's a big chance that it'll do a lot of good; there's a small chance that it won't help at all; but there's no chance that taking it could ever hurt.