Like I said, my TRT/HRT knowledge is pretty basic man. I imagine it all depends on what levels your hormones are at, how much you take of what you want and what your goals are. For example, if your goal on TRT was to correct an issue and eventually be brought off, I wouldn't be screwing with my hormones in any manner. You mentioned feeding some upper level hormones. If that was really needed then perhaps TRT isn't right for a person, but HRT would be. Though, if one was content being on TRT/HRT, with a good understanding on how all these affect the body any of the PH/AAS etc are still possible. Just need to be aware of cause and effect for things.