Sorry for bumping this thread if my question/concern is not relative to the original topic but for the sake of not creating another thread, I believe it is. I understand that this question may have already been addressed but I keep reading counter arguments and debates on the matter. So I want to just ask this once and hopefully I'll be able to receive a productive answer, once and for all. There have been questions and concerns regarding 3,5-T2 about its potential suppressive effect on TSH. On the other side, there have also been questions in regards to 3,3-T2 and if it has any effect at all on TSH.
So my question is does 3,5-T2 actually cause suppressive effects, when used ONLY in a manner as directed and cycled? And does 3,3-T2 have any positive effects at all on TSH, UCP activity, and overall energy expenditure?
I've gathered up as many studies as I can find relevant to this question. From what I've gathered, I came to the understanding that 3,5-T2 can be suppressive if used in supraphysiological doses. I have yet to be conclusive on 3,3-T2 in regards to having any thyroidmimetic properties. I'm bringing this up because I still have my TT-33 from the New Year's sale and would really like to run it, but just want to make sure that there really is no need for PCT, although I, personally, would still run something (like LX) afterwards, just to be safe. Also because there is another popular product out right now that claims that 3,5-T2 does cause suppression of TSH and is why it is not included in their product. I am not going to say who or what product it is, but it is at Nutra and it's not hard to guess. I am also not calling them out, but as a consumer it's hard to find something conclusive on the matter and would just like a solid answer. Here are the studies that I've gathered for now.
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Also I understand all of these weren't done in vivo, but I'm a little short time here.