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Phophatidylserine

nobel252

Member
Planning to take 800mgs daily to lower cortisol. Is best to take it one time a day after my workout or should I take 400mgs before workout and 400 after workout. From what I heard it seems like it's best to take the whole 800mgs after training. I'm Also on TRT 100mgs of test e once a week. I know that this lowers cortisol pretty good so would I still need to supplement with phosphatidylserine. Ive always had high cortisol because I run around 30 miles a week and I lift weights. Thanks for any advice
 
PS can drop cortisol too well and cause joint discomfort in some people. The rule I follow is 300mg every day or 800mg three times per week.

Personally I would take it post workout or in the evenings. Cortisol influences training drive so it wouldn't be wise on paper to have it low for your workout.

I hope this helps.
 
bdcc said:
PS can drop cortisol too well and cause joint discomfort in some people. The rule I follow is 300mg every day or 800mg three times per week.

Personally I would take it post workout or in the evenings. Cortisol influences training drive so it wouldn't be wise on paper to have it low for your workout.
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really? Cause I'm pretty sure that having really low cortisol causes aggression, which can be good for strength and intensity in the gym (this is supposedly why the AAS Halotestin works so well to increase aggression for athletic competitions and pre-contest training).
 
nobel252 said:
Planning to take 800mgs daily to lower cortisol. Is best to take it one time a day after my workout or should I take 400mgs before workout and 400 after workout. From what I heard it seems like it's best to take the whole 800mgs after training. I'm Also on TRT 100mgs of test e once a week. I know that this lowers cortisol pretty good so would I still need to supplement with phosphatidylserine. Ive always had high cortisol because I run around 30 miles a week and I lift weights. Thanks for any advice
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Take on the morning you need wait to the body builds up then you feel the Full Effects.
 
Phosphatidylserine is a cortisol modulator, not inhibitor, so don't worry about it plummeting to non-existent levels and causing joint discomfort.

Because of this, it is best to take first thing in the morning as Maxximal suggested, or shortly prior to training, as that will keep cortisol from spiking as your workout progresses. An intra-workout shake will help potentiate this effect as well.

Have you looked into Invalid Link Removed It provides a full dose of PS and several other phosphatidyl acids, as well as a 600mg dose of A-GPC.
 
Resolve said:
Phosphatidylserine is a cortisol modulator, not inhibitor, so don't worry about it plummeting to non-existent levels and causing joint discomfort.

Because of this, it is best to take first thing in the morning as Maxximal suggested, or shortly prior to training, as that will keep cortisol from spiking as your workout progresses. An intra-workout shake will help potentiate this effect as well.

Have you looked into Invalid Link Removed It provides a full dose of PS and several other phosphatidyl acids, as well as a 600mg dose of A-GPC.
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Yeap Invalid Link Removed is a AWESOME cortisol modulator try and see!
 
Resolve said:
Phosphatidylserine is a cortisol modulator, not inhibitor, so don't worry about it plummeting to non-existent levels and causing joint discomfort.

Because of this, it is best to take first thing in the morning as Maxximal suggested, or shortly prior to training, as that will keep cortisol from spiking as your workout progresses. An intra-workout shake will help potentiate this effect as well.

Have you looked into Invalid Link Removed It provides a full dose of PS and several other phosphatidyl acids, as well as a 600mg dose of A-GPC.
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Is Anserine similar?
 
Resolve said:
I haven't heard of anserine having cortisol modulating effects, but I haven't read much on it. From what I understand, it's function is still largely unknown, but it has serum glucose lowering effects probably through a mechanism involving carnosine.
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It is in VPX's BCAA nit. formula Power Shock (which I love). It is a dipeptide found in muscles that helps reduce fatigue and also helps to scavenge free radicals.
 
Resolve said:
Happen to know how?

Edit: Thanks, BTW. :)
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Absolutely not! Haha, I am entirely willing to admit when I am limited or void on further information on a subject. I did find some evidence that it is related to carnosine muscle content though "The pKa of the imidazole ring of histidine, when contained in anserine, is 7.04, making it an effective buffer at physiologic pH.[2]."

I sure do like my Power Shock though :) I am intrigued by this compound and would like to discuss it more - new thread perhaps?

Have a good one :)
 
Im using endoamp in pct...seems to be working well.
 
Resolve- a PT I know has suffered joint discomfort from taking too much.

Charles Poliquin has literally just posted on PS and mentions 2400mg per week being his maximum for the same reason. I am happy to take his recommendation on this one.

Invalid Link Removed
 
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