Peg-mgf Guide (pdf)

papapumpsd

papapumpsd

Well-known member
YO YO, I came across this PDF guide on PEG-MGF and thought I'd share it with everyone. I cannot comment on the accuracy of the information. It's just another source of info to possibly base your decisions on!

If ANYONE has info on IGF-1 + Peg-MGF protocols, please send them my way or post in here. I'm interested in dosing (details) and post cycle gains (and post-post cycle gains....as the new muscle cells take a while to mature).

Thanks and happy reading!
 

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To be fair I will point out that it was written by the company that made it, so its kinda like their word against nobody's. Not that this is bad, I just hear actual results vary greatly from the hype. Igf-lr3 seems to beat this stuff 10-fold in real world feedback. Just my opinion here. I would like to try it and see for myself, but I still need to read some logs.
 
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TripDog said:
To be fair I will point out that it was written by the company that made it, so its kinda like their word against nobody's. Not that this is bad, I just hear actual results vary greatly from the hype. Igf-lr3 seems to beat this stuff 10-fold in real world feedback. Just my opinion here. I would like to try it and see for myself, but I still need to read some logs.
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YES, excellent point! The article was written by the company that makes the PEG-MGF.

I have cross-referenced some of what the articles says with what Grunt76 says (injections, dilutions, etc). The article doesn't really talk about gains (mentions them briefly), and doesn't seem to be hyping what Peg-MGF will do for you.

It didn't come off as being biased, BUT, as always, this guide should be used IN CONJUNCTION with other knowledge.

Thank you for your heads-up Trip. Also, the only legit source for PMGF is this company (according to Grunt76 as well).
 
papapumpsd said:
YES, excellent point! The article was written by the company that makes the PEG-MGF.

I have cross-referenced some of what the articles says with what Grunt76 says (injections, dilutions, etc). The article doesn't really talk about gains (mentions them briefly), and doesn't seem to be hyping what Peg-MGF will do for you.

It didn't come off as being biased, BUT, as always, this guide should be used IN CONJUNCTION with other knowledge.

Thank you for your heads-up Trip. Also, the only legit source for PMGF is this company (according to Grunt76 as well).
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i can assure you that this company is NOT the only legit source of pegmgf. this was maybe the case when it was first produced but is no longer true.
 
Good read. It does say igf with pegmgf is better than individually taking it.
 
pumbertot said:
i can assure you that this company is NOT the only legit source of pegmgf. this was maybe the case when it was first produced but is no longer true.
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Pumbertot, thank you very much for the claificiation. I re-referenced the original source whom indicated that this company was the only true source of Peg-MGF, and it was stated a while ago. My apologies everyone. Apparently there is another (others) manufacturers available today.
 
good thing i found this thread, i was going to post the same. This is some other stuff probably from the same place papa found it....





This was written by FinaFreak. from OSBB

Most of us are familiar with the peptides Insulin-Like Growth Factor (IGF) and Mechano Growth Factor (MGF). We know things like IGF creates new muscle cells and helps drop body fat and MGF helps facilitate this muscle growth and fat loss.

In the beginning:

When IGF first made its way onto the bodybuilding scene most people were injecting it every day and noticed that after somewhere around 30 days the effects of IGF wore off. This was blamed on receptor "down-regulation" or "desensitization". To combat this people started a 5-on 2-off rotation and then went to a post workout only rotation which extended the time on IGF an additional 10-20 days. But the problem with the lack of "receptor response" was still present.

Then MGF came onto the scene. MGF was suppose to be the next best thing in bodybuilding. It was suppose to be more anabolic than AAS and better suited for building new muscle than IGF, the problem was that it wasn't. Because of its instability it was quickly broken down once injected into the body, to prevent this PegMGF was created. This new MGF was now able to survive in the body from anywhere in the 1-3 days. Combining this new peptide discovery with IGF was suppose to be able to make all of us the next Mr. Olympia. But what happened? Why do we not see a flood of new pros?

What happened:

In theory these two peptides should cause some great results, the problem is they do not work together very well unless your timing is spot on (I will go into greater detail later). In short stem cells in the presence of MGF will cause the cells to split and multiply. When the cells are multiplying they cannot form new tissue and the effects of IGF are completely blocked. So the two together are not very compatible.

Then why not just use IGF? Well most do use IGF only and get great results, but there is that pesky business of receptor "down-regulation" or "desensitization" and you have to end a cycle of IGF after 30-50 days and there is no way to prevent it... or is there?

The science:

In a natural system (Our Body) we have peaks and dips with MGF and IGF levels. The reasons for these peaks and dips are to create the ideal amount of cells to repair and create new tissue. After strenuous exercise the levels of MGF in the body (more specifically in the muscle just trained) increase dramatically and there is a dramatic decrease of IGF levels. The reason for this is because MGF causes stem cells to proliferate (split and multiply). This process ensures that there are enough cells available to make repairs and to create new tissue in order for the tissue to function efficiently and properly (in this case skeletal muscle tissue). As mentioned above in the presence of MGF there is no need for IGF because it is rendered useless and cannot activate the stem cells, so this explains the bodies response to decrease IGF levels.

In 12-36 hours MGF levels begin to drop and there is a direct correlation in the rise of IGF levels within the body. Stem cells have proliferated and now the IGF will bind to the proper receptors and cause differentiation (force the stem cells to form into a specific cell for a specific tissue type). This process repeats every time you exercise and keeps the natural system in an efficient state.

When flooding the body with these artificial peptides a person will change this natural system dramatically. A person using MGF only is causing stem cell proliferation while at the same time preventing IGF to perform its duties of creating new tissue from those newly created stem cells. A person using IGF only is depleting the supply of stem cells at a rate much faster than the body can keep up, leading to a depletion of available stem cells and not receptor "down-regulation" or "desensitization."

This sounds like a lose-lose situation. You are throwing off your body's final tuned muscle repairing mechanism, depleting valuable stem cells or creating too many stem cells for your body to deal with. Why bother?

The climax:

The reason why we bother is because we want to reach or goals. We want to be the biggest bodybuilder, the best powerlifter or whatever it is that we are training so hard for. These peptides are a great addition to our arsenal, but learning to use them properly is the key to utilizing their benefits.

The key is retraining the way we think about MGF and IGF. We have to understand that we are dealing with the creation and depletion of stem cells that are going to be responsible for our muscular growth. Our bodies do not have a constant supply of these stem cells and our bodies will not naturally utilize all of the stem cells it has created. Since we are trying to artificially manipulate the amount and utilization of these stem cells we have to look at this is a different manner.

While we may never get the exogenous MGF and IGF levels just right so that we may counteract the depletion of the stem cells we can adjust our protocols in a way that will increase the amount of time a person can use and respond to both peptides.

The Conclusion Part 1, MGF:

We know that the PegMGF will stay in the body for several days and we know that while in the presence of MGF stem cells will proliferate and the use of IGF is futile. We also know that MGF without the peg is of little to no help because of how quickly exogenous MGF is broken down within the body. So what are the options?

Well both can be of use! PegMGF can be of great use as long as the individual using the peptide in conjuction with IGF understands that the two peptides must be injected in a manner that falls outside of the current way of thinking. And MGF without the Peg addition can also be utilized as long as you don't mind being a pin cushion.

The key with MGF is to learn to either follow your bodies natural peaks and dips of MGF levels and force proliferation on a larger scale with MGF, or to force a longer period of cell proliferation with the use of PegMGF. The key is you have to have stem cells in order to create new muscle tissue.

The Conclusion Part 2, IGF:

Now that we have hit the MGF part of the cycle, now we move into the part of the cycle that utilizes the stem cells. Again we want to either follow the body's natural peaks and dips of IGF levels or we are going to want to cause a prolonged forced differentiation phase. The latter of the two options is simply following standard protocol of everyday injections or 5-on 2-off. The other is all about timing. We know that MGF levels peak in the body after strenuous exercise, so why would you want to inject a substance that is useless in the presence of MGF right when MGF levels are at their highest? The answer is you don't! You will want to wait and inject the IGF 24hrs after the exercise. This will give ample time for the MGF peak to start to dip and can closely mimic the natural rise in IGF levels. This will allow for a person to use a more efficient dose since the timing of the IGF will correspond closely to the dip in MGF levels resulting in greater utilization of the exogenous IGF.

The cycles:

There are a few cycles I would recommend.

The first being IGF only. It works, maybe not the most efficient plan out there but it does work none-the-less.

The second would be the PegMGF/IGF combination. This is not the most efficient methos but should significantly increase the amount of time one can be on an MGF/IGF cycle and still see positive results. (This may have to be altered according to your training schedule)

Sunday - Off Training - Mid-day PegMGF 200-300mcg
Monday - Training (Afternoon)
Tuesday - Off Training - Afternoon IGF 40-80mcg
Wednesday - Training (Afternoon)
Thursday - Off Training - Afternoon IGF 40-80mcg
Friday - Training (Afternoon)
Saturday - Off Training - Afternoon IGF Injection 40-80mcg

The addition of the PegMGF will cause an increase in amount and duration of stem cell proliferation and should subside about the period of the first IGF injection. While this will not keep stem cell levels stable it should prevent the drastic decrease in stem cell numbers seen with IGF only cycles and should significantly increase cycle length.

The third would be the use of regular MGF plus the addition of IGF and woulld closely mimic the natural system.

Sunday - Off Training
Monday - Training (afternoon) - 1hr PWO MGF 50mcg in muscles trained
Tuesday - Off Training - Afternoon IGF 40-80mcg
Wednesday - Training (Afternoon) - 1hr PWO MGF 50mcg in muscles trained
Thursday - Off Training - Afternoon IGF 40-80mcg
Friday - Training (Afternoon) - 1hr PWO MGF 50mcg in muscles trained
Saturday - Off Training - Afternoon IGF 40-80mcg

This protocol should closely mimic natural peaks and dips in MGF and IGF within the specific muscles being trained. While regular MGF is short lived in the body the addition on the regular MGF 1 hour post workout should cause an increase in cell proliferation beyond the natural system's ability and should create a larger pool of stem cells for the utilization of IGF therapy.
 
thats one of the first articles i ever read on peptides and i never thought it made any sense then or now. igf on non-training days is just plain stupid. igf receptors are upregulated immediateyl PWO, thats the time to pin it.
 
pumbertot said:
thats one of the first articles i ever read on peptides and i never thought it made any sense then or now. igf on non-training days is just plain stupid. igf receptors are upregulated immediateyl PWO, thats the time to pin it.
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so you are saying you dont believe in pinning igflr3 any other time but postwo?
 
pistonpump said:
so you are saying you dont believe in pinning igflr3 any other time but postwo?
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yes for maximising hyperplasia/hypertrophy it has to be immediately PWO. it seems wasteful/inefficient to inject it any other time for that purpose.

of course for speeding up healing of injuries/surgery its used differently, as I will be doing myself next month.
 
pumbertot said:
yes for maximising hyperplasia/hypertrophy it has to be immediately PWO. it seems wasteful/inefficient to inject it any other time for that purpose.

of course for speeding up healing of injuries/surgery its used differently, as I will be doing myself next month.
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Yep. I totally agree. Listen to Pumber as this is sound and excellent advice.

If you pin IGF any other time rather than PWO, you are not agonising the maximum PWO IGF-1 receptor saturation window, and thus more of the local IGF-1 is unused by the skeletal muscle and absorbed systemically instead. Not only is the skeletal muscle receptor agonism less efficient, but also more of the local IGF-1 application is absorbed and made systemic...
A waste of IGF for starters, and also more non sleletal muscle receptors are being agonised in the rest of the body that we don't want... (intestines, etc)
 
pumbertot said:
yes for maximising hyperplasia/hypertrophy it has to be immediately PWO. it seems wasteful/inefficient to inject it any other time for that purpose.

of course for speeding up healing of injuries/surgery its used differently, as I will be doing myself next month.
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I have to agree as well, shooting 80-100mcg on non training days really makes no sense at all..
 
I can't imaging 100mcg on ANY DAY and ANY TIME would be helpful. Seems like way too much. 50mcg +- 10mcg I have heard is ideal for most. Again, this is what I have read, not from experience :D
 
PWO is ideal for IGF..now how would you run the MGF during that?? im just jumping on here now and havent done much reading yet(which ill do for a long time tonight)but BOB invited me over(great guy..lol and knows his ****) so im just chiming in right now
 
rippedfreak123 said:
PWO is ideal for IGF..now how would you run the MGF during that?? im just jumping on here now and havent done much reading yet(which ill do for a long time tonight)but BOB invited me over (great guy..lol and knows his ****) so im just chiming in right now
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I'm trying to figure that out myself......and Bob is the man.
 
TripDog said:
I'm trying to figure that out myself......and Bob is the man.
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no bad words?? ohh fuk..im a big cursor..gotta watch my mouth on this board

from wat ive been reading.. a good protocol might be something likes this..bob or others please chime in as i might run mgf and igf with my current cycle right now..

sunday-mgf 200 mcgs

mon-wed-fri- long r3

wat do you guys think??

i had ran longr3 by itself mon-fri 5 on 2 off and worked well, imma give the 3 times a week a try due to the longer life..
 
According to Grunt76 ( I believe it was him), you take the MGF at least 12 hrs prior to IGF. Shoot the MGF at bedtime. 2x each week.
 
papapumpsd said:
According to Grunt76 ( I believe it was him), you take the MGF at least 12 hrs prior to IGF. Shoot the MGF at bedtime. 2x each week.
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ok but your kinda contradicitng yourself.. your saying before bed but yet wat if you go to the gym in the afternoon??
lets say for example

ill take mgf at 7 30 and go to the gym at 7 in the afternoon then shoot up the IGF??

also wat if you go to the gym both morning and afternoon...i split my work outs twice a day..im not a big fan of being in the gym for 2 hours at a time
 
rippedfreak123 said:
ok but your kinda contradicitng yourself.. your saying before bed but yet wat if you go to the gym in the afternoon??
lets say for example

ill take mgf at 7 30 and go to the gym at 7 in the afternoon then shoot up the IGF??

also wat if you go to the gym both morning and afternoon...i split my work outs twice a day..im not a big fan of being in the gym for 2 hours at a time
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Sorry Ripped, I was assuming you did evening workouts. So on Monday night (for example), you would shoot Peg-MFG. Now get your sleep on. After at least 12 hrs passes from your PMFG shot, you will take your IGF-1 (post W/O, IM, bilaterally).

***I CANNOT address how you might do split workouts. The above is for one single workout.

Any of you mega experts care to address this?
 
I just ordered 4mg of PEG, so i'm going to do some experimenting, and put up a log. I'm almost thinking several small doses...not sure yet though.
 
papapumpsd said:
Sorry Ripped, I was assuming you did evening workouts. So on Monday night (for example), you would shoot Peg-MFG. Now get your sleep on. After at least 12 hrs passes from your PMFG shot, you will take your IGF-1 (post W/O, IM, bilaterally).

***I CANNOT address how you might do split workouts. The above is for one single workout.

Any of you mega experts care to address this?
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wats your theory based on doing it before bed?? due to the 12 hour time your basing on??
 
rippedfreak123 said:
wats your theory based on doing it before bed?? due to the 12 hour time your basing on??
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I cannot claim it is my theory. An IGF-1 board guru recommends this I believe to minimize competitive binding so-to-speak with the IGF-1. Assuming you're using PEG-MGF, it has a much much longer 1/2 life vs. non-PEG version. Thus, it is floating around your system much longer and it may interfere with the IGF-1 shot.

If I recall correctly this is why you administer it at least 12 hrs apart from IGF-1.

Hope this helps.
 
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