Haha!Mullet - let me put it in context closer to your heart... It's like someone making you eat your pancakes with that Mrs. Buttersworth crap you find in the grocery store.
Haha!Mullet - let me put it in context closer to your heart... It's like someone making you eat your pancakes with that Mrs. Buttersworth crap you find in the grocery store.
whoa! mullet that wasnt' cool!Watch out for this one: He may PM you asking for pictures of your wife, Snag [true story].
:nutkick:
:welcome: Well hellz, welcome to the board man!first post ever
No, Andrew PM'ed me today asking me for pictures of my fiance! I was saying the same may happen.whoa! mullet that wasnt' cool!
Haha.. Timber! Bringing his Timber-esqueness to the fray! :lol:Honestly though... SuperCissus - no joke - is the ONLY supplement I can think of off the top of my head that does what its supposed to in less than 3 days - and just like Snagglicious said - its one of the only supplements that you miss as soon as its gone.
Its like that one chick that wasn't too cute, but could suck the color out of a marble... It was fun to dump her... you saved a few dollars... but life just isn't the same.
This would have been funnier had I explained the joke.Watch out for this one: He may PM you asking for pictures of your wife, Snag [true story].
:nutkick:
there was a reason though, anyways all in good nature, I assume we could trade gf pics, LOL:thumbsup:No, Andrew PM'ed me today asking me for pictures of my fiance! I was saying the same may happen.
[In fun, though]
Uh, I'll pass. Thanks.there was a reason though, anyways all in good nature, I assume we could trade gf pics, LOL:thumbsup:
LOL..thats what i meant, thats not cool you would p.m him a picture and not me!:lol:....J.K!..:lol:No, Andrew PM'ed me today asking me for pictures of my fiance! I was saying the same may happen.
[In fun, though]
you have the supply's that's for sure. every bit helps.This log will be like a slowly developing storm {the BIGGER} that hopefully, by it's conclusion, will be wreaking some havoc with serious gale-force {the FASTER} winds of demolishing {the STRONGER} destruction!
(also, I wanted to tweak the title of the thread a bit so as not to infringe on copyright issues..)
Here's the situation physically at the current time: Partly cloudy with a chance of rain.. I will be coming back from the double-whammy of some knee/tendon issues that have been recurring the last few months, but now seem to be subsided; as well as a stomach virus that knocked my ass down for 3 days last week (during 2 of which I could eat practically nothing), lingered into the weekend and is now gone - but dropped 10 lbs. of bodyweight off me. Weight upon rising this morning was 186 (ugggh), down from my off-season bulking peak of 207 just 6 short weeks ago.. first time I've been sick in over 3 years, so I guess I can't complain.
The joint issues I've been experiencing on & off are always eliminated (for me) by mega-dosing SuperCissusRx; this time is no different. I'm currently dosing 2 caps, 10 minutes prior to every meal (so 6x daily). I will eventually drop this to 1 cap prior to every meal, and then to maintenance levels. I should mention this is not a sponsored log; I'm a USP athlete, so of course my base will always be some of these products. That's just a given. All the other supps I have purchased myself (even additional quantities of SuperCissus, which I need to run at my preferred dosage) -- altho I do have to add that I've got a source that allows me to get ridiculous deals on these items, which makes it very attractive to me to try some new things.
Other supps in the mix:
USPlabs:
Jacked (3 scoops prior to training)
Prime (3 caps @ 3x daily)
Recreate (2 caps prior to w/o, 1 mid-afternoon, going to 2 eventually)
PowerFULL (3 caps prior to training, 3 caps @ bedtime, SAT & SUN off)
AP & Pslin (either one of these with virtually every meal)
SuperCissusRx (format listed above)
NXLabs
Plasmavol (2 TBS prior to training, stacked w/ Jacked)
*This is a new item for me; the whole Mannitol/Glycerol thing intrigues me.
MRI:
Anabolic Switch (3 scoops immediately following training)
NO2 Black (4 tabs upon rising, 4 tabs mid-day)
ProNOS
ProGainer
Diesel Nutrition:
Diesel Test Hardcore (1 tab 3x daily to start, increasing to 2 tabs 3x daily)
*This is a new item for me, excited to see the synergy this produces when combined with Prime!
Beverly International:
Super Pak (w/ breakfast)
Ultra Size (one of THE best protein complexes in the world imo)
Ultra 40 Liver Tabs (a staple for me; 4 tabs/meal)
CytoSport
MonsterMilk
Optimum Nutrition
NitroCore 24
And some staples..
Udo's Oil
Fish Oil
EVOO
Leucine/BCAA's
Beta-Alanine
Ashwagandha
1000mg addt'l vit C
400 iu vit E
thinking of possibly adding Posiedon.. but I'm not decisive here
(UPDATING IN PROGRESS... STAY TUNED FOR MORE WEATHER ALERTS!)
I'm getting uncomfortable... and that's rare.there was a reason though, anyways all in good nature, I assume we could trade gf pics, LOL:thumbsup:
Didn't know you were into dudes, its all good, just never ask me for my number and were good, regardless I can not show pics of my girl, yet, she is shy, what gives:lol:Okay, you asked for her:
Didn't know you were into dudes, its all good, just never ask me for my number and were good, regardless I can not show pics of my girl, yet, she is shy, what gives:lol:
View attachment 25068
I was uncomfortable about two hours ago when he PM'ed me asking for pictures of my GF.I'm getting uncomfortable... and that's rare.
wow!..mullet your a very lucky man,congrats on the twins!..when is he due?..HAHAHAHAHA!:lol:
Sorry Snag-o-rama. All done!All right, no hijacking the thread to trade pics of your chicks, or any other such things. Not allowed! You will be banned! :banned:
Hahahahahahahaha, this is awesome misunderstanding, it is making my day, oh so humorous, and I will let you continue your thread bro, my bad for this weird inconvenienceI was uncomfortable about two hours ago when he PM'ed me asking for pictures of my GF.
thats what i sai too much bullshit not allowed some play and fun is fine too much is too much. lets talk about training, diet, supplementation and all things bodybuilding and add about 5% goof offAll right, no hijacking the thread to trade pics of your chicks, or any other such things. Not allowed! You will be banned! :banned:
Quoting myself, ahaa..Cool.
Ohh.. and FOG, I'm warning you right up front.. :nono:
I figured you were when you said that. and maybe semi serious..wasnt totally sure and thought you were playing...alright enough for holding this up. I asked some bodybuilding questions the last page of page two. can you answer them?Quoting myself, ahaa..
Just so everybody doesn't think I'm a total dick, FOG knows I was just joking here.. :trout:
Earlier I said I hope to have time tomorrow to fill in diet/training parameters. Too tired tonight, going to bed right now in fact..you have the supply's that's for sure. every bit helps.
whats the diet like...and how often do you eat how many grams of protein do you get per day?
of course carbs are individual and depend on the goal and fat is individual? some people don't count when not6 competing some do. do you?
also will you be posting reps, sets and poundage used, I'd like to see this.
do you currently compete in shows?
Nah, no worries bro.. I like what Timber brings to the table! And Mullet too.. I don't want to have guys thinking they can't speak their mind in here, about any issue. By all means - that's how some interesting discussions take off!Your left (picture's right) bicep tattoo is badass. I've been thinking about a similar one (only larger) across my chest and shoulder. Big decision!!!
Oh, and apologies for the off track banter. I think in most threads I'm guilty of 85% of that, so I'll keep it to a minimum!!
Aside from that, you're looking lean and mean... Looking forward to the explosion.
Yeah, Russian here as well. I like the old hammer and sickle. I think it speaks to a time where Russia had a lot of pride and power and pretty much instilled fear in other world superpowers. Union might be dead, but the sybolism is still there. Rocky IV - end of story.Nah, no worries bro.. I like what Timber brings to the table! And Mullet too.. I don't want to have guys thinking they can't speak their mind in here, about any issue. By all means - that's how some interesting discussions take off!
But some things I can just do without. Not trying to be a dick at all, just wanted to nip that particular issue in the bud..
So you're talking about my hammer & sickle? Yeah, I'm Russian as you know, and I got that back in the 80's when it was the Soviet Union flag. Shortly after I got it, the Union disbanded.. oh well.
Wow, 25 posts worth . . . with nothing .. Let's keep Snag's new log/thread cleaner, PLEASE !
I have been having a discussion based on GLUT4 receptor specificity [ability of AP to selectively regulate GLUT4 mRNA expression in muscle {myocytes} cells or fat {adipocytes} cells]. Here is the discussion taken from that other website. May be of some benefit to some!AGREE, or else I'll send a nastyright out of my lab to get all of you off-topic hijackers :lol:
I like your stack Snag and the science behind it :thumbsup:
You are looking:
I've read the claims...I've tried AP/Pslin...enjoy the pumps..however, I still question the ability of it's claims:
1) to Upregulate Glut-4 receptors selectively only in Muscle cells and not adipose
2) How does AP selectively inhibit PPAR gamma (which by inference AP has to be an allosteric inhibitor for FFAs, PGs, LTs)...according to the claims, this is not proven, they just measured mRNA expression of the PPAR)
3) the drug class Thiazolidinediones (used in Diabetes) binds to PPARs and actually increases insulin sensitivity/decrease resistance. How can USP labs claim to INHIBIT PPAR gamma yet increase insulin sensitivity SELECTIVELY in skeletal muscle...
Just curious as to see if there are any theoretical pathways that would make sense...to put the puzzle pieces together
1) The clinical data (albeit in IDDM/NIDDM and rat models) reflects as such; though it is impossible to state AGU is not occurring. However, with that being said, fuel provision is of secondary concern when lipid metabolism - and therein proliferation and differentiation - is being directly controlled.
2) Berberine directly activates AMPk in peripheral tissues, via mitochondrial respiration inhibition; thereby creating a fluctuation in the extracellular AMP:ATP ratio, and creating a demand for AMPk in respects to glucose phosphorylation for energy provision. Data has reflected a 6-16h increase in AMPk levels. This is important for the following reason: AMPk directly inhibits co-activator p3000, inhibits PEPCK through transcription, ACC (and thereby inhibits malonyl-cOA) both at transcriptional and post-translational, as well exerting transcriptional control over PPAR-y, and its target enzyme CPT-1. AMPk, and therefore AP (data reflects a direct and immediate regulation of AMPk in skeletomuscular tissue), selectively regulates PPAR-y via transcriptional factor control, and by the inhibition of co-activation factors, rather than direct site-binding. It selectively regulates PPAR-y, due to p3000 being an AMPk substrate; direct binding is not necessary.
3) Actually, and ironically enough, the most recent data is proposing that Thiazolidinediones' Insulin Sensitizing effect is via mechanisms independent of PPAR-y regulated gene transcription; in actuality, and to therefore answer your question, TZDs are now being shown to directly and acutely increase phosphorylation of AMPk. Whereas previous studies into TZD administration postulated that TZD mediated decreases in Insulin resistance were due to adipogenesis induction (and thereby decreased levels of FA, and storage of TGs - direct precursors to Insulin insensitivity), it is now being realized their action is via AMPk induction in skeletal muscle. As a result, Berberine is especially attractive as alternative NIDDM/IDDM, due to its weight loss induction via transcriptional control over the PPAR target enzyme CPT-1; thereby increasing mitochondrial B-Oxidation of FAs, rather than decreasing it. This anti-lipogenic action, combined with increased glucose uptake in myocytes, inhibition of cholesterol and TG synthesis, and more efficient response to energy demands, creates a recomposition effect on tissue via preferential use of energy.
Further, this Berberine mediated AMPk phosphorylation has (as of yet, at least) been most prominent in skeletal muscle. As stated, AMPk is a more direct regulator of the glucose metabolism pathway than that of PPAR-y (direct upregulation of GLUT4 translocation, and more direct control over lipogenesis); in this respect, the secondary pathways of PPAR-y become irrelevant, as they are more or less circumvented by AMPk. Berberine decreases mitochondrial respiration, thereby increasing the AMP:ATP ratio, increasing AMPk phosphorylation and inducing intracellular glycolysis; thereby having an additive effect on Insulin sensitivity.
Finally, to answer your first question in a round about manner, the inhibition of mitochondrial respiration via Complex-I has only been noted in L6 myotubes, and not adipocytes. In this respect, the response to intracellular glucose demand is not specific, but merely the respiratory response of AMPk; in this light, the AMP:ATP ratio modulation by Berberine, and therefore increased phosphorylation of AMPk is myocyte specific, rather than GLUT4 specificity.
The insulemic pathway is far more diverse than PPAR-y mRNA expression, or even PPAR-regulated gene transcription factors. A more direct approach to Insulin/Glucose modulation was necessary due to the additive effects on adipose posed by PPAR-modulating medications. In all respects, AMPk is the key regulator of energy expenditure pathways. Once the true role of AMPk mediated, Insulin-independent glucose metabolism is elucidated, PPAR-y/a modulation becomes of secondary concern (though, it is still important to keep in mind AMPk mediated PPAR-a induction in skeletal muscle, leading to increased FA oxidation, and thereby increases in stamina and endurance). I hope that was exact enough. j/k.
That's why I need the Mulletia up in heah.. :afro:http://www.shmu.edu.cn/courses/2008aut/20080916/20081016/Zhangzeng Berberine_ a Natural Plant__ Product_ Activates AMP-Activated protein kinase with beneficial metabolic__ effects in diabetic and insulin-resistant states.pdf
This is the full text where all I said above is validated - and the study where a reduction in adipocyte cell line mRNA was shown.
Hells yeah! Here is an index for all those abbreviations:That's why I need the Mulletia up in heah.. :afro:
Ahh, thanx big guy! You guys sure make my deflated ego feel a bit better. I think I look like dogshit personally, but that's what happens when you get steamrolled by a MACK truck! But realistically, I should be filled back up within a few good days of training/eating.Snag, you are looking straight swole-da-fukk-up!! :headayummmm!!
I can't wait to see the "after" photos.
By Odin's beard, you're gonna look freaky!! :twisted:
RUSSIA!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! RUSKI SILA!!!Yeah, Russian here as well. I like the old hammer and sickle. I think it speaks to a time where Russia had a lot of pride and power and pretty much instilled fear in other world superpowers. Union might be dead, but the sybolism is still there. Rocky IV - end of story.
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