Trauma1
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This thread will contain all of the Dermatherm logs for your easy viewing pleasure, as well as the write-up below. I'll continue to update this as they roll in.
http://anabolicminds.com/forum/supplement-reviews-logs/125510-dermatherm-target-new.html?highlight=dermatherm
http://anabolicminds.com/forum/supplement-reviews-logs/121636-cuttin-up-primordial.html?highlight=primordial
http://anabolicminds.com/forum/primordial-performance/130062-rosies-review-dermatherm.html
http://anabolicminds.com/forum/supplement-reviews-logs/131097-primordial-performance-dermatherm.html
What is DermaTherm Target?
DermaTherm Target is a topical cream that targets and dissolves fat upon the site of application. The formula dries within minutes, leaving the skin clean and moisturized. At the recommended dose, DermaTherm Target will last up to 60 days.
Dropping body fat can be as simple as reducing carbohydrates, increasing protein while going into an overall calorie deficit. However, even with the perfect diet and exercise program, there are certain areas of the body that "hold on" to fat tissue no matter how much weight you lose - and this is where DermaTherm Target offers a distinct advantage - it targets and releases stubborn body fat, converting it to usable energy.
DermaTherm Target was designed to enhance the rate of fat loss in site specific areas, thus offering an easy way to fine-tune your physique. It's the secret weapon for turning a flat stomach in to a hard and chiseled six-pack.
How does DermaTherm Target "target" fat loss?
DermaTherm accomplishes a targeted action by delivering the small, light weight ingredients deep within the adipose tissue via our OHV topical delivery system.
The targeted dissolution of fat is accomplished by delivering the active ingredients through the skin and directly into the fat cells where they can oxidize and "dissolve" stubborn fat tissue.
How does DermaTherm Target "dissolve" fat tissue?
The term "dissolve" refers to the breakdown of fat by lipase, which is the most important step in burning off body fat. In order for the body to use fat as an energy source, the fat must be broken down to simple fatty acids. (6) This process is known as lipolysis, and DermaTherm Target increases lipolysis by increasing lipase activity, and the breakdown of fat.
Thus, DermaTherm Target helps "dissolve" stored fat. Once the fat tissue is dissolved it becomes usable energy, where it gets sent to the mitochondria, and gets burned off.
In other words, DermaTherm pulls fat from the fridge and puts it to the furnace.
What results should I expect with DermaTherm Target?
Upon the site of application, DermaTherm Target can offer the following benefits -
Reduced bloat and water retention
Enhanced muscular definition
Harder & more vascular looking physique
Improved tone and tightness of flabby areas
Note: Clinical human studies have shown that maximum results may take up to 12 weeks to realize.* (8,9) Best results are obtained when calories are restricted and below normal maintenance levels.
What are the ingredients, and how does it work?
The first ingredient that increases lipase activity is a naturally occurring alkaloid known as theophylline which has been proven to be an effective "spot reducer" in several human studies where it was shown to reduce fat tissue around the abdominal and thigh area upon topical application. (5,8-11)
On a cellular level, theophylline increases lipase activity by stimulating cAMP (cyclic adenosine monophosphate), causing downstream activation of protein kinase A, resulting in a subsequent increase in lipase activity at the adipocyte (fat cell). (1-5) Remember, lipase is the fat dissolving enzyme required to breakdown fat, so it can actually be burned off.
Raspberry ketone is another ingredient proven to assist in lipolysis. (7) More specifically, Raspberry ketone increases the transport of lipase from the cytosol to the lipid droplets in the fat cell - putting it right where it needs to be to dissolve fat tissue. (7)
The next ingredient which further catalyzes the lipase response is evoidamine. This alkaloid from the Evodia Fruit has been shown to be a powerful inducer of "lipolytic activity" by dramatically increasing the lipase activity from norepinephrine stimulation. (12) Evodiamine also contributes to fat loss by increasing insulin sensitivity. By increasing insulin sensitivity, you can potentially reduce circulating insulin levels, and intensify lipase activity. You see, insulin is a major suppressor of lipolysis because it is a "storage" hormone that wants to store bodyfat, not release it. Therefore reducing circulating insulin levels will encourage lipolytic activity, and therefore increase the release of fatty acids to be burned off as energy (the main reason low-carb diets are so effective).
Trans-cinnamaldehyde is another ingredient that dramatically increases insulin sensitivity (13-17). Again, increasing insulin sensitivity can reduce circulating insulin levels, which will initiate the lipolytic process. Trans-cinnamaldehyde is aromatic molecule extracted from cinnamon, which also happens to be a powerful vasodilator for increasing permeation of actives ingredients through the skin. (18-19)
Does DermaTherm Target have any side effects?
At the recommended dose, DermaTherm Target is safe for men and women. Because the active stimulants in DermaTherm Target are primarily active at the site of application, typical side-effects such as anxiety, heart palpitations, and insomnia are rare. However, it is still recommended that the product only be used early in the day and not within 8 hours of bedtime.
Note: DermaTherm Target may leave the skin warm, red or slightly tingly for approximately 30-40 minutes after application.
DermaTherm Target
6.0
Characteristics:
Fast drying creamy lotion, possessing a hot botanical cinnamon scent.
Active Ingredients:
Active ingredients per 2 pumps -
Theophylline – 50mg
Raspberry Ketone – 44mg
Evodiamine – 23mg
Trans-cinnamaldehyde – 17mg
Other Ingredients:
Distilled water, grape spirits*, aloe vera*, ethoxy diglycol, dimethyl isosorbide, jojoba oil, emu oil, squalene, tocopherol acetate, chamomile extract* (matricaria recutita), isopropyl myristate, green tea extract* (camellia sinensis), cetyl palmitate, sorbitan palmitate, sorbitan olivate, glyceryl stearate, PEG 100 stearate, glycerin, dimethicone, strontium nitrate, hydroxypropyl methylcellulose, tetrahydropiperine†, potassium sorbate, sodium benzoate, sodium PCA, sodium hydroxide.
* Certified Organic
† US Patent 6,849,645
