its up alreadyWhen?
its up alreadyWhen?
The compound'seffects are dose/concentration dependent in terms of which molecular target itengages. As described in the USPlabs' patent, at a specified lower dose, thecompound possesses a thermogenic and cognitive effect, while at a much higher dose, thecompound possesses an anabolic effect.Isnt aegeline in the new version of oxyelite pro , guess I do not understand the big deal of this product .. Yet the alpha testers seemed to really like it..
I did find this http://www.banlab.com/hearbs_details_popup.php?hear*****23
Aegle marmelos (alkaloidal-amide, Aegeline 2) lowered blood glucose levels by 12.9% and 16.9% at 5 and 24h, respectively, in sucrose challenged streptozotocin induced diabetic rats model at the dose of 100mg/kg body weight. Aegeline 2 has also significantly decreased the plasma triglyceride (Tg) level by 55% (P<0.001), total cholesterol (TC) by 24% (P<0.05) and free fatty acids (FFA) by 24%, accompanied with increase in HDL-C by 28% and HDL-C/TC ratio by 66% in dyslipidemic hamster model at the dose of 50 mg/kg body weight. The compound 2 might be a beta(3)-AR agonist[SUP]13[/SUP].
I've seen this exact phrase word for word on another board, that you? or is every usp rep been told to say that in regards to the questions regarding the ingredients?The compound'seffects are dose/concentration dependent in terms of which molecular target itengages. As described in the USPlabs' patent, at a specified lower dose, thecompound possesses a thermogenic and cognitive effect, while at a much higher dose, thecompound possesses an anabolic effect.
The anabolic amount makes subjects extremely hungry. You obviously don't want that in a Fat burner/appetite suppressant.
I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?Is this data human data? Because its octopamine metabolites are very weak b-3 agonists on human adipocytes.
Correct, if asked the difference between OEP and VERSA-1 that is the companies answer..I've seen this exact phrase word for word on another board, that you? or is every usp rep been told to say that in regards to the questions regarding the ingredients?
mine too i always brabo/lapel choke everyone.Darce is one of my favorite chokes.
Probably is a great word in science.According to High Tower Pharmacology , aegeline MAY be inherently anabolic, however will probably not affect humans. Great.
Have to love the sneaky chokes....so quick.mine too i always brabo/lapel choke everyone.
200 or so placebo guys raving about it all month just like you did.I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?
If the primary metabolite is octopamine or an analogue, I will be very disappointed. Anecdotally, I got great pumps from the product, which I'm not even sure is a possible endpoint even if aegeline is metabolically active. I will never rule out placebo though, as I was not blinded.
We'll see. I hope it works, I couldn't pass on the deal . Figured if I dont like it I can always sell the 2nd bottle on ebay for about 50 anyway.Probably is a great word in science.
I know you're confident in the product (otherwise why patent it?). Any strings attached with the guarantee? I'd like to try 3 caps/day200 or so placebo guys raving about it all month just like you did.
100 percent money back.....although you will get more on eBay with this deal then if returned at the super low purchase price.
He said anabolic in adipose tissue lol. Cissus round 2!According to High Tower Pharmacology , aegeline MAY be inherently anabolic, however will probably not affect humans. Great.
I will first say three caps is overkill. You are basing off data on glucose. We are not claiming that.I know you're confident in the product (otherwise why patent it?). Any strings attached with the guarantee? I'd like to try 3 caps/day
You also receive a bottle of a month supply of agmatine500We'll see. I hope it works, I couldn't pass on the deal . Figured if I dont like it I can always sell the 2nd bottle on ebay for about 50 anyway.
I actually agree with this post 100%. I don't know enough about the product as there simply isn't a whole lot of data on aegeline. I think people should make their own educated decisions here.With all the hype, why is everyone suddenly dubious now that Coop chimes in with a few doubts? Don't get me wrong, scepticism is a good thing in the supplement industry but no need to try make it out like USP is facilitating a huge scam, after all, a tonne of money would have been put into research/ development and patenting the product; none of which would be worthwhile if the product is too be doomed.
I can't wait for it to drop on the planet; considering I cannot get the IC release here in NZ
Edit: Not a shot at Coop, so don't hate on me
We will publish the animal studies (90 day study in Rats and Rabbits is not cheap) and in the middle of recruiting subjects for a study at Memphis. before release, we conducted a pilot study on safety markers (as discussed in the write up).With all the hype, why is everyone suddenly dubious now that Coop chimes in with a few doubts? Don't get me wrong, scepticism is a good thing in the supplement industry but no need to try make it out like USP is facilitating a huge scam, after all, a tonne of money would have been put into research/ development and patenting the product; none of which would be worthwhile if the product is too be doomed.
I can't wait for it to drop on the planet; considering I cannot get the IC release here in NZ
Edit: Not a shot at Coop, so don't hate on me
Same here.I used the product and loved it, so i bought the IC release.
The competition will manipulate data to serve there purposes...I used the product and loved it, so i bought the IC release.
While the anabolic in adipose tissue confuses me i know i was cutting and never saw signs of impaired fatloss.
Lulz, wowzers... I wasn't that hurt, just thought the logical thing to do is extend the timeframe considering the down time... uspl will make sure everyone gets a chance to take advantage of it, I'm sure.Same here, hit the link seconds after recieving and nothing and nothing since. This is quite disapointing since its been hyped in our heads for months. Its like waking up christmas morning to only find out that your house was robbed and all the presents stolen
exactly.After all the evidence shown in beta-testers.....
wonder if there was some shake-n-bake agmatine in the beta testers supplements (ironic the IC release includes it given the pump people are saying they get)I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?
If the primary metabolite is octopamine or an analogue, I will be very disappointed. Anecdotally, I got great pumps from the product, which I'm not even sure is a possible endpoint even if aegeline is metabolically active. I will never rule out placebo though, as I was not blinded.
I think if it was placebo one of the many guys that are incredibly in tune with what their body can do and how it reacts to most supplementation would have called farce. And there was absolutely no marketing to be had or tip offs to testers of what possible effects may be, the effects came with great proof and were individually reported.Not really. The placebo effect can dupe anyone, especially if it is trumped up with exceptional marketing.
Someone here is confused, Sir, and it is not I.You are very confused. The placebo effect is not malingering or "lying," it is completely unintentional. Anyone is susceptible to its effects.
Anyone and everyone are two completely different things.Anyone is susceptible to its effects.
Tone and emphasis are completely lost through conversing via text my friend.You seem quite hostile.
Your stating that testers are the victim of a placebo run. I was one of the testers. I'm stating my effects were not that of a placebo run. Bottom line.I'm curious, what is your secondary gain for defending a bottle full of pills? Surely they can defend themselves in efficacy, or through USP labs marketing bombardment?
Why would you ever want to train like a human?Do you have to train like a beast for this product to work or training like a human being would suffice ?
I'd love to read it.I wrote a science based article and you have subjective history littered with broscience ("deeerp it wasn't placebo cuz i said it wasn't").
Susceptibility to a neurological placebo effect and definitive quantifiable physiological responses beyond that which placebo(sugar/water usually) can provide are 2 different things.You can't determine your own susceptibility to the placebo effect.
Holy ****, it feels like I'm trying to teach a poptart quantum physics.
Bottom line.
Mind facked? HahahahahahahaSusceptibility to a neurological placebo effect and definitive quantifiable physiological responses beyond that which placebo(sugar/water usually) can provide are 2 different things.
It is impossible for sugar water in combination with resistance weight training and cardio to provide me with as dramatic results as which I achieved. I've been weight training naturally and supplemented for over 11 years and understand what my body is capable of doing under which circumstances.
Therefore I can determine whether or not my end physiological results were or were not that of a placebo run.
Susceptibility to being mind facked and bodies defying natural science are 2 different things.
the pop tart comment was hilarious.
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Is the patent complete? Or just filed?We will publish the animal studies (90 day study in Rats and Rabbits is not cheap) and in the middle of recruiting subjects for a study at Memphis. before release, we conducted a pilot study on safety markers (as discussed in the write up).
Companies search available (as we do) to develop a product, but in this case, we are creating the research. There are pros and cons to it.
Pro- we are the first and with the patent, we can liscense it out..
Cons- Innovation doesn't come without attacks from the competition....it's the nature of the industry.
Susceptibility to a neurological placebo effect and definitive quantifiable physiological responses beyond that which placebo(sugar/water usually) can provide are 2 different things.
It is impossible for sugar water in combination with resistance weight training and cardio to provide me with as dramatic results as which I achieved. I've been weight training naturally and supplemented for over 11 years and understand what my body is capable of doing under which circumstances.
Therefore I can determine whether or not my end physiological results were or were not that of a placebo run.
Susceptibility to being mind facked and bodies defying natural science are 2 different things.
the pop tart comment was hilarious.
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They didn't know what to expect. We didn't make claims. We just handed it out and said take it...if you believe enough that something is going to happen you can trick your body. Placebo. And its very real.
For example if you believe youre taking a fat burner that HAS to work because it has awesome reviews, and you truly believe in it but someone you ended up with sugar pill. You would probably still lose fat because you believe it so much and visualize yourself losing fat. Pretty crazy
Intense rise in body heat and Nausea ? Ill pass.Where did iron fists posts go? Objective discussion and a disagreement of viewpoints should not be grounds for deletion. I just got here and am reading a broken convo lol.
Anecdotally, I did notice transient bouts of almost unbearable sweating when combined with caffeine in a fasted state. That, and nitrate-esque vascularity, were the two most prominent effects for me (the citocholine may explain the erections). I'd like to get iron fists take on these effects and possible causes. Vascularity observations could be placebo or subject's bias, but the intense rise in body heat (with sweating and even some nausea) was only present when I took this product fasted, and it occurred without fail when doing so.
Some may view those as positives (thermogenesis and appetite suppression). It wasn't unpleasant because the effect lasted only a matter of minutes before I could proceed with my workout.Intense rise in body heat and Nausea ? Ill pass.
Sucks they deleted dudes post tho shows the politics sides of the game
Sounds like a fever to me man hahahaSome may view those as positives (thermogenesis and appetite suppression). It wasn't unpleasant because the effect lasted only a matter of minutes before I could proceed with my workout.
Lol! I'm just after the "why?" as usual so I hope usplabs or iron fist can chime in because my ability to dissect aegeline is limited by the present data.Sounds like a fever to me man hahaha
completely understand.Sounds like a fever to me man hahaha
Real talk tho I don't like to take fairly new mystery ingredients main reason why I'm not buying it has nothing to do with your comment I was just joking
Was this for beta testers only?How do I use?
What supplements can't I use with the Patented anabolic?
Do not use any other ergogenic supplements like Compound 20, Test Powder, PRIME, or any supplements in the ergogenic category.
What supplements can I use?
We URGE you to stack with your pre-workout or thermogenic of choice. If you're using both a pre-workout and a thermogenic; ON workout days stack with pre-workout and on off days stack with thermogenic.
Yes, beta-testers only. There are a few threads of persons stacking versa-1 with other usplabs supps!Was this for beta testers only?
Edit: didn't mean to post in this thread but I guess it could get answered here too
1cap of versa-1 per day will deliver awesome results! I do not recommend doing any more than that.This is my first time running an anabolic should I stick to one pill a day with my thermo or maybe two?