We will be doing a special tomorrow, make sure you are on our email list to get informed: https://www.strongsupplementshop.com/email-sign-upAny introduction deal on this?
Hey Bud,The link provides claims the following:
Source 1 "double testosterone production in animals" - Source one claims that GGOH enhances testosterone and progesterone in I-10 cells. This is an invitro study, not in live specimens.
Source 3 - The study linked here shows performance enhancement in seniors. Is there any data showing performance enhancement in normal demographics, especially in males who are established weight lifters/athletes?
Source 4 - You guys have "source 3" twice in the sources section.
Well, with respect to question 1: It's not (just) an in vitro study.The link provides claims the following:
Source 1 "double testosterone production in animals" - Source one claims that GGOH enhances testosterone and progesterone in I-10 cells. This is an invitro study, not in live specimens.
Source 3 - The study linked here shows performance enhancement in seniors. Is there any data showing performance enhancement in normal demographics, especially in males who are established weight lifters/athletes?
Source 4 - You guys have "source 3" twice in the sources section.
Any bloodwork on this?Well, with respect to question 1: It's not (just) an in vitro study.
View attachment 171356
As for source 3: There are good reviews here and here. The former focuses on the ingredient's ergogenic potential, the latter on its virility enhancing properties.
...And a particularly interesting point -- which is mentioned in the first review -- is that this extract is known to facilitate and accelerate the conversion of progesterone and pregnenolone to testosterone, via activation of CYP17 (17a-hyroxylase/17,20 lyase). So you can see how this would pair well with GGOH; the ingredients of this product were selected to compliment each other.
All that said, I understand where you're coming from, and we're going to put out more detailed write-ups ASAP.
Did you guys do the original write up here? Because I was thoroughly shocked when they announced it was an Antaeus product. Your write ups are usually a lot better than that. Anyway, looking forward to more info.Well, with respect to question 1: It's not (just) an in vitro study.
View attachment 171356
As for source 3: There are good reviews here and here. The former focuses on the ingredient's ergogenic potential, the latter on its virility enhancing properties.
...And a particularly interesting point -- which is mentioned in the first review -- is that this extract is known to facilitate and accelerate the conversion of progesterone and pregnenolone to testosterone, via activation of CYP17 (17a-hyroxylase/17,20 lyase). So you can see how this would pair well with GGOH; the ingredients of this product were selected to compliment each other.
All that said, I understand where you're coming from, and we're going to put out more detailed write-ups ASAP.
We've been using the product here for months, and we've been working on it for years. We've run through a bunch of iterations -- including a very complicated one with chrysin nanoparticles. (That one's a real long story...) The current version, which is the culmination of a long process, has seen a lot of use here -- and we wouldn't release it if feedback and results weren't exceptional.Once again. And I know from experience with other supp companies im probably wasting my time, any bloodwork on this or is it just the rats that have been made buff? Cant work out why it's in iiquid form if it has so much oral bioavailability???
I just bought two bottles! Wanna pay for my blood work ��We've been using the product here for months, and we've been working on it for years. We've run through a bunch of iterations -- including a very complicated one with chrysin nanoparticles. (That one's a real long story...) The current version, which is the culmination of a long process, has seen a lot of use here -- and we wouldn't release it if feedback and results weren't exceptional.
But don't take it from us. In all things, the best and most reliable results and feedback come from impartial and unbiased third parties. What do you say we send you a free bottle and pay for your blood tests? PM me.
And the product is a liquid because most of the active ingredients are liquid.
The geranylgeraniol comes from a liquid annatto extract, and the ingredient itself is a liquid in pure form. Phytol, similarly, is a liquid in pure form. It's basically impossible to turn those liquid ingredients into solids -- not, at least, without heroic efforts, like adsorption onto aerosil or porous zeolites.
And then there's the fact that Tongkat Ali is actually traditionally taken as a liquid extract, and many of the studies which examine it have used it in liquid form.
Moreover, that K2 and D3 are not only fat-soluble, but should exhibit better and more complete absorption when pre-dissolved into liquid formulations.
Ultimately, it was a pretty simple decision to release it as a liquid. Especially as it doesn't taste like much and is very easy to take.
Thats a bold move, and I like when companies put their money where their mouth is.But don't take it from us. In all things, the best and most reliable results and feedback come from impartial and unbiased third parties. What do you say we send you a free bottle and pay for your blood tests? PM me.
Good point. Very observant, too.Thats a bold move, and I like when companies put their money where their mouth is.
But, that doesnt resolve the question of why you dont have bloodwork now. Surely it would make sense to have that kind of data to use as a part of claims made with your product. Youve had the product for months, why not have some of the people using it get bloods done?
We would suggest that you take it with the last meal of your day, but I don't think that it makes too much of a difference.Is there a best time of day to does?
No known effect. It's extremely likely that there's no meaningful effect at 5-alpha reductase.Any effects on the 5ar enzyme?
Is there much benefit to doubling the dose? The label seems a little vague. Take one serving per day but don’t exceed two. I’m not familiar with dosing strategies on the new compounds in this product as they are, naturally, new.We would suggest that you take it with the last meal of your day, but I don't think that it makes too much of a difference.
Eurycoma longfolia has a few known mechanisms of action that are of relevance here.I thought TA had an effect on DHT?
dermacrine stacks well with 'ALMOST' everything...at 43 you should see some nice benefits from it!!!Firstly please excuse my ignorance. I have bought Ultra Test which i cant wait to try by the way being 43 years old this could be just what i need.
My question is in a few weeks ill be finishing my current Invictus VII KT stack and will then look at using Ultra Test and i have some Dermacrine and 4-AD gathering dust in my cuboard. Could I stack Ultra Test with either of these products and if so what would be better and what would one 'expect' benefits wise??
Obviously nobody can be 100% exact on results but i would appreciate your expert opinion/advice. Hopefully us older guys are in for a treat with Ultra Test.
Thanks buddy i shall give Dermacrine a whirl alongside Ultra Test and see how that goes.dermacrine stacks well with 'ALMOST' everything...at 43 you should see some nice benefits from it!!!
I’m unclear on this... I’d thought you’re supposed to run sustain after dermacrine, but now I see you can stack it. Which way is it?dermacrine stacks well with 'ALMOST' everything...at 43 you should see some nice benefits from it!!!
Jake offered me this 4-6 months ago, I'd have to check my email to be sure of an exact date.Thats a bold move, and I like when companies put their money where their mouth is.
But, that doesnt resolve the question of why you dont have bloodwork now. Surely it would make sense to have that kind of data to use as a part of claims made with your product. Youve had the product for months, why not have some of the people using it get bloods done?
That's a good question, and the point needs clarification.Is there much benefit to doubling the dose? The label seems a little vague. Take one serving per day but don’t exceed two. I’m not familiar with dosing strategies on the new compounds in this product as they are, naturally, new.
Firstly please excuse my ignorance. I have bought Ultra Test which i cant wait to try by the way being 43 years old this could be just what i need.
My question is in a few weeks ill be finishing my current Invictus VII KT stack and will then look at using Ultra Test and i have some Dermacrine and 4-AD gathering dust in my cuboard. Could I stack Ultra Test with either of these products and if so what would be better and what would one 'expect' benefits wise??
Obviously nobody can be 100% exact on results but i would appreciate your expert opinion/advice. Hopefully us older guys are in for a treat with Ultra Test.
In short, cAMP/PKA can potentially enhance androgen receptor signalling -- and this effect seems to be independent of whether that testosterone is endogenous or not.Several studies in the mid-late 1990s demonstrated that AR could
be stimulated by elevated cAMP levels. In 1994, Ikonen et al.
demonstrated that rat AR transactivation by testosterone could be
enhanced by the PKA stimulators; forskolin (an activator of adenylate
cyclase) and 8-bromo-cAMP (8-Br-cAMP, a cAMP analogue) in
monkey kidney CV-1 cells cotransfected with an AR expression
plasmid [20]. Synergistic stimulation of AR by androgen and PKA
activators was dependent upon intact AR DNA- and ligand-binding
domains. Two years later, Nazareth and Weigel demonstrated
androgen-independent stimulation of human AR by forskolin in
both CV-1 cells, and PC-3 prostate carcinoma cells transfected with AR
[21]. Nazareth and Weigel observed that neither R1881 (methyltrienolone,
a synthetic androgen analogue) nor forskolin increased AR
protein levels, but rather enhanced the AR activity by increasing AR–
DNA binding. These results suggested that other aspects of AR
interactions with additional co-activators and/or transcription factors
may also be affected by forskolin/cAMP, however the exact mechanisms
underlying this androgen-independent stimulation remained
unclear
[. . .]
In a 2005 study by Kim and others, a novel mechanism of PKA–AR
cross-talk was uncovered and confirmed that PKA activation can
enhance androgen-dependent transcription.
Thank you for clarification on dosing!Ultratest and Dermacrine compliment each other, and they should work exceptionally well together. Sounds like a great combo to me.
The 4AD question is complicated.
The easy answer is that it would be sub-optimal to use Ultratest alongside anything suppressive, like 4AD.
Having said that, geranylgeraniol's effects are cAMP/PKA-mediated, and there's a lot of cross-talk between cAMP/PKA and the androgen receptor. From this study: https://www.ncbi.nlm.nih.gov/pubmed/20813184
In short, cAMP/PKA can potentially enhance androgen receptor signalling -- and this effect seems to be independent of whether that testosterone is endogenous or not.
So it's at least possible that Ultratest can enhance "on-cycle" effects. We plan on looking into this with animal experiments over the coming year. Of course, the primary and intended use of the product is as a testosterone booster which augments endogenous production...
either or is fine...personally I don't feel dermacrine requires a pct, especially after a short run of a month or even 2, but running sustain alpha after dermacrine would have the pct base covered really well.I’m unclear on this... I’d thought you’re supposed to run sustain after dermacrine, but now I see you can stack it. Which way is it?
Have sent you a PM. I hope I fit the profileWe've been using the product here for months, and we've been working on it for years. We've run through a bunch of iterations -- including a very complicated one with chrysin nanoparticles. (That one's a real long story...) The current version, which is the culmination of a long process, has seen a lot of use here -- and we wouldn't release it if feedback and results weren't exceptional.
But don't take it from us. In all things, the best and most reliable results and feedback come from impartial and unbiased third parties. What do you say we send you a free bottle and pay for your blood tests? PM me.
And the product is a liquid because most of the active ingredients are liquid.
The geranylgeraniol comes from a liquid annatto extract, and the ingredient itself is a liquid in pure form. Phytol, similarly, is a liquid in pure form. It's basically impossible to turn those liquid ingredients into solids -- not, at least, without heroic efforts, like adsorption onto aerosil or porous zeolites.
And then there's the fact that Tongkat Ali is actually traditionally taken as a liquid extract, and many of the studies which examine it have used it in liquid form.
Moreover, that K2 and D3 are not only fat-soluble, but should exhibit better and more complete absorption when pre-dissolved into liquid formulations.
Ultimately, it was a pretty simple decision to release it as a liquid. Especially as it doesn't taste like much and is very easy to take.
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