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The Official OL UK Ghar1ne Q&A

i ordered a few cognitive boosters

Oxiracetam , phenibut, more noopept ( which seems to be less effective over time)
hopefully these will help with mental energy
 
i ordered a few cognitive boosters

Oxiracetam , phenibut, more noopept ( which seems to be less effective over time)
hopefully these will help with mental energy

I've been using a lot of Biotest Brain Candy lately. If that can't take you out of a fog, nothing can!

Ha, ha! Yeah, maybe that's why I'm not very lathargic!
 
I'm starting to see a lot of talk on Internet about lethargy and crappy workouts with 677. How long until it passes? Thinking of starting ghari1ne first before the rad
hit hard o not I use iforce maxout as a preworkout and that shiat gets me up n running .
so a good preworkout should do.
 
I was wondering if we could get someone on the formulation side to comment. I've been going on label instructions which are listed here:

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and that is to dose with a meal -- not an empty stomach.

Now my initial thought would have been empty stomach, pre-bed, but I've followed the label.

Should I be dosing empty stomach?

To be honest, because of it's mechanism of action, it shouldn't matter how it is taken. It should be effective regardless. Now, whether taking it 'with food' is optimal compared to taking it on an 'empty stomach', my personal recommendation would be on an empty stomach. However, considering the versatility of MK-677, it is recommended for those cutting and bulking. So for those bulking, taking it with a meal may be unavoidable if your stomach is rarely ever empty. It's also recommended to dose more than once per day if bulking, making it even more difficult to take it on an empty stomach. Yet there are logs out there of people bulking on MK-677 with success, so if that is an indication of anything, it's that it doesn't inhibit it's effectiveness. So while I cannot say why the label indicates taking it with a meal, I can assure you the product should remain effect regardless of when you take it.
 
To be honest, because of it's mechanism of action, it shouldn't matter how it is taken. It should be effective regardless. Now, whether taking it 'with food' is optimal compared to taking it on an 'empty stomach', my personal recommendation would be on an empty stomach. However, considering the versatility of MK-677, it is recommended for those cutting and bulking. So for those bulking, taking it with a meal may be unavoidable if your stomach is rarely ever empty. It's also recommended to dose more than once per day if bulking, making it even more difficult to take it on an empty stomach. Yet there are logs out there of people bulking on MK-677 with success, so if that is an indication of anything, it's that it doesn't inhibit it's effectiveness. So while I cannot say why the label indicates taking it with a meal, I can assure you the product should remain effect regardless of when you take it.

And that's what I was thinking -- that it is a marginal difference on an empty stomach or not. I was just curious if Olympus had a specific reason for the recommendation rather than saying 20-30 minutes before a meal or something like that.

I'll go empty stomach tonight and see if I notice anything (i doubt I will).
 
I think they are associating it with ghrp administration . Perhaps that can explain the empty stomach encouraged administration
 
I would think if you can't rearrange you meal schedule, early morning on an empty stomach is your other option.

How does this affect how you feel during the day? Does it make you sleepy and so forth during the day if you take it in the morning? Never taken this before obviously, and I suppose you could say I'm "bulking" as I'm pretty much eating constantly from before my first class to before I go to bed.
So I'm trying to figure out the best time to take my doses. I can always experiment and mess around with dosing times and conditions regarding meals and so forth but it's always good to get others' experiences as well and determine the best route to maybe start with.
 
How does this affect how you feel during the day? Does it make you sleepy and so forth during the day if you take it in the morning? Never taken this before obviously, and I suppose you could say I'm "bulking" as I'm pretty much eating constantly from before my first class to before I go to bed.
So I'm trying to figure out the best time to take my doses. I can always experiment and mess around with dosing times and conditions regarding meals and so forth but it's always good to get others' experiences as well and determine the best route to maybe start with.

I was just saying if he couldn't take it on an empty stomach at night due to his eating schedule, he could switch to morning's. Now, maybe food will have no effect on it as Hastur says, I'm merely speculating based on GH use.

I've not used it in the mornings, just before bed.
 
I know that's why you said it, I'm just inquiring because I may run into the same problem, as I am almost always eating when I am awake.

I was just wondering if taking it in the morning would make you want to sleep all day, or if you would still only notice that effect at night and just experience increased hunger during the day regardless of when you take your dose.
 
From what I've seen so far its hit or miss.. People getting tired throughout the day even with night time dosage.
 
From what I've seen so far its hit or miss.. People getting tired throughout the day even with night time dosage.

Yeah, probably doesn't make a big difference.
But to be safe I will probably take it before my first class every morning, as I usually don't consume any carbs until after that class. Usually a protein shake or bad on my way to or during class. So I'll probably start out taking the gharine upon waking just to see what happens.
Maybe I'll do mornings the first week and nights the second week and compare and contrast.
 
I look forward to your results! I love hearing feedback on this. It's one of the most interesting compounds to me.
 
Agreed. Growth hormone in the body has always been really interesting to me.

I may do a log just for sh*ts and giggles. Already got a log going but maybe will do one for this too
 
It's for my bulk.
 
Another thought I had was increased prolactin; has anyone had any issues with this in regards to MK 677 supplementation? I already have pramipexole on hand from back in the day (last year...) when trenavar was still on the market. Lol. So I may run that at a low dose during this MK cycle.
I am already using letrozole to combat some gyno issues I'm currently having and once that clears up I also have aromasin and nolvadex on hand.

Also, just my 2 cents after reading a small portion of this thread: I have never taken a BLR product (and I have taken a few) and thought, "Wow! That worked really well!" But I have never taken their letrone product so I don't have an opinion on how well that works.
I look forward to hearing some feedback! Thanks guys.

I believe I'm pretty sensitive to prolactin-related sides, since Ive had painful nipples coming off of stuff that is not supposed to even be "hormonal". I been on mk-677 for about 6 weeks and haven't had any of these sides.
 
I believe I'm pretty sensitive to prolactin-related sides, since Ive had painful nipples coming off of stuff that is not supposed to even be "hormonal". I been on mk-677 for about 6 weeks and haven't had any of these sides.

Never know whether you were getting what you thought in those other products. Always concerning when that haappens.
Could be just how your body reacts or something shady :(
 
5 weeks on gharine. 20 days at 10mg+ 200mcg huperzineA, 15 days at 20mg+200mcg huperzineA.
I take gharine 1h after my dinner before bed and HuperzineA when I wake up.
For the first 20 days at 10mg I've noticed a deeper sleep, when I up at 20mg lethargy like walking dead during 2 days, just want to eat and sleep. Despite that, I stayed at 20mg but the day 3 was good no lethargy but the bloat start especially on my middle section. I notice my hands and fingers to tingle the next day and my forearms to feel tight.
But now no bloat or lethargy, I wake up very refresh and very vascular. I want to up at 30mg and stay during 6 months or 12 months for see the real effect.
About huperzine A how long can I take it ? 3, 6 months or I have to clycle it ?
 
is this user dependent? There's conflicting reports of when to take it, morning or night. I take 20mg before bed and even upped it to 30mg last night and it gave me terrible insomnia. I'm afraid to dose it in the morning since I read it causes lethargy during the day. I guess I'll take it first thing in the morning tomorrow and find out...
 
I know that's why you said it, I'm just inquiring because I may run into the same problem, as I am almost always eating when I am awake.

I was just wondering if taking it in the morning would make you want to sleep all day, or if you would still only notice that effect at night and just experience increased hunger during the day regardless of when you take your dose.

Sorry, BamBam, I don't have any experience running it that way.
 
UPDATE:

1) I'm at 7 weeks, 4 or 5 weeks (I'd have to check) @ 30 Mg.

2) I gave up on the pre-bed huperzine a while back (or huperzine, period); it just had too many side effects for me, maybe because I jack with my acetylcholine levels enough without the huperzine.

3) I then found that a 10 Mg. dose of melatonin approximately doubled the GH response to GHRP (presumably because it inhibits somatostatin), so I figured I'd give it a try.

4) the melatonin worked well for about the first week, but then I started waking a little too frequently, having a little too restless of sleep.

5) last night I decided to leave off the melatonin. Well, I got an incredible sleep: much deeper, less waking to pee, and very tingly hands again!
I think the problem may lie in the form of melatonin used. Regular quick release melatonin has a very short half-life--about 2.5 hours--often causing a disturbance in the sleep cycle. Researchers suggest using time release melatonin In order to more closely mimic the body's natural release pattern.
I've also found claims that large bolus doses of melatonin may desensitize the brain to melatonin's effects.

6) I will be trying time release to see if it works better. Part of the problem is there is actually very little in the way of studies on the effects of chronic dosing of melatonin, in whatever dose.

7) in the meantime, I'll be looking into other natural somatostatin inhibitors.
 
UPDATE:

1) I'm at 7 weeks, 4 or 5 weeks (I'd have to check) @ 30 Mg.

2) I gave up on the pre-bed huperzine a while back (or huperzine, period); it just had too many side effects for me, maybe because I jack with my acetylcholine levels enough without the huperzine.

3) I then found that a 10 Mg. dose of melatonin approximately doubled the GH response to GHRP (presumably because it inhibits somatostatin), so I figured I'd give it a try.

4) the melatonin worked well for about the first week, but then I started waking a little too frequently, having a little too restless of sleep.

5) last night I decided to leave off the melatonin. Well, I got an incredible sleep: much deeper, less waking to pee, and very tingly hands again!
I think the problem may lie in the form of melatonin used. Regular quick release melatonin has a very short half-life--about 2.5 hours--often causing a disturbance in the sleep cycle. Researchers suggest using time release melatonin In order to more closely mimic the body's natural release pattern.
I've also found claims that large bolus doses of melatonin may desensitize the brain to melatonin's effects.

6) I will be trying time release to see if it works better. Part of the problem is there is actually very little in the way of studies on the effects of chronic dosing of melatonin, in whatever dose.

7) in the meantime, I'll be looking into other natural somatostatin inhibitors.

Great feedback, especially on the Melatonin. I know I build a tolerance pretty quickly to it. I might look into time released options as well.

As for other somatostatin inhibitors look at CDP-choline:

Administration of CDP-choline in healthy elderly adults resulted in a four-fold increase in serum GH levels, compared with baseline values.

Ceda GP, Ceresini G, Denti L, et al. Effects of cytidine 5'-diphosphocholine administration on basal and growth hormon< -releasing honnone-induced growth homione secretion in elderly subjects. Acta Endocrino! {Copenhl. 1991 May;124(5):5I6-20.
 
Great feedback, especially on the Melatonin. I know I build a tolerance pretty quickly to it. I might look into time released options as well.

As for other somatostatin inhibitors look at CDP-choline:

Administration of CDP-choline in healthy elderly adults resulted in a four-fold increase in serum GH levels, compared with baseline values.

Ceda GP, Ceresini G, Denti L, et al. Effects of cytidine 5'-diphosphocholine administration on basal and growth hormon< -releasing honnone-induced growth homione secretion in elderly subjects. Acta Endocrino! {Copenhl. 1991 May;124(5):5I6-20.

Yeah, the problem with the CDP choline is that I take Alpha-Gpc pre-training. Again, I'm hesitant to Jack with acetylcholine levels too much.

I also use Biotest Brain Candy often (though not always) before my morning walks-- it contains CDP choline.
 
Yeah, the problem with the CDP choline is that I take Alpha-Gpc pre-training. Again, I'm hesitant to Jack with acetylcholine levels too much.

I also use Biotest Brain Candy often (though not always) before my morning walks-- it contains CDP choline.

Understandable. I'm going to be looking into alternative somatostatin inhibitors anyway so I'll likely post back here with a list of what I found.
 
Coming late to the party. Started reading yesterday just now finished. I will be starting ghar1ine Friday night. It seems for the most part nobody really noticed bloating until 20mg or higher. Did anyone notice bloating with around 10mg doses?
 
Coming late to the party. Started reading yesterday just now finished. I will be starting ghar1ine Friday night. It seems for the most part nobody really noticed bloating until 20mg or higher. Did anyone notice bloating with around 10mg doses?

Yes.
 
I am water logged and bloated . On 10mg only . Lethargy is worst side ....makes me want to stop using

It will get better brother. Just stick with it. Lethargy was the worst I have ever felt, and like you was only 10mg. Lasted about 3 weeks. Im up to 20 now and haven't had any lethargy since it initially presented itself
 
I am water logged and bloated . On 10mg only . Lethargy is worst side ....makes me want to stop using

Bro its been about 5 wks and no change :(

You are on a lot of other compounds as well still, right? Having made several changes as well, correct? This MIGHT impact your lethargy. Or even be more of the cause, depending on a multitude of factors. Lay it all out, maybe we can help get your energy back.
 
You are on a lot of other compounds as well still, right? Having made several changes as well, correct? This MIGHT impact your lethargy. Or even be more of the cause, depending on a multitude of factors. Lay it all out, maybe we can help get your energy back.

Test Prop 300mg EW
Triumph ( just started) 3 caps ED
ghar1ne 1 cap pre bed ED
Cardarine 14mg ED
Tribulus 750mg x 3 ED
Hawthorne berry
Turmeric
Tudca 3 caps per day (OL brand)
Equipoise 500mg EW
Raloxifene 60mg e3d
Exemestane 25mg eOd

May drop the eq and sub for masteron - androgens seem to give me more energy and drive
el1minate lands this week I wiill be using 3 caps per day or 4

perhaps my androgens are too low or test levels
I'll be honest I have ****ty sex drive and my balls are mildly atrophied
take 250mcg hcg every few weeks. (2x per week when i do it). it helps but i ran out
 
ok, so I took 20mg this morning along with Conqu3r Demigod mixed with 60g lecithin granules preworkout. It's been 2 hours since I left the gym and I still have a pump. I'm not sure if there's a synergy between these compounds or I just respond well dosing Ghar1ne in the morning. I'll check back later to see if lethargy occurs since it's too early to tell, but for now my energy is good and I'm alert.
 
Olympus UK has a lot of interesting stuff I'm interested in, yet vaguely scared of. After reading this thread, Ghar1ne looks interesting. For the least amount of side effects, I assume the best thing to do is dose it near bed, and on an empty stomach? I'm trying to avoid all of those hunger issues/lethargy issues that people are talking of in this thread. Also, in someone who's "younger" (26), would this stuff be useful or not?
 
Olympus UK has a lot of interesting stuff I'm interested in, yet vaguely scared of. After reading this thread, Ghar1ne looks interesting. For the least amount of side effects, I assume the best thing to do is dose it near bed, and on an empty stomach? I'm trying to avoid all of those hunger issues/lethargy issues that people are talking of in this thread. Also, in someone who's "younger" (26), would this stuff be useful or not?

Yes it would.

MK-677 (Ghar1ne) actually worked even better in younger individuals, causing an even greater spike in GH. And GH in general has a lot of health benefits even outside of those related to physical performance and recovery.
 
Olympus UK has a lot of interesting stuff I'm interested in, yet vaguely scared of. After reading this thread, Ghar1ne looks interesting. For the least amount of side effects, I assume the best thing to do is dose it near bed, and on an empty stomach? I'm trying to avoid all of those hunger issues/lethargy issues that people are talking of in this thread. Also, in someone who's "younger" (26), would this stuff be useful or not?

All my doses have been pre bed and the lethargy still hit like a brick wall
 
That didn't work either. My pre workout at the time was a full scoop of Stimul8 around 11am. Only difference was the addition of Ghar1ne. Between the hrs of 4 and 6, lethargy would come crashing down. Never failed.
 
That didn't work either. My pre workout at the time was a full scoop of Stimul8 around 11am. Only difference was the addition of Ghar1ne. Between the hrs of 4 and 6, lethargy would come crashing down. Never failed.

That's sucks I take iforce maxout only when needed, and u didn't need it for awhile now ! I'm almost at 1 month of gharine usage the only thing I can complain about is bloat and it's kinda going away.
 
i used c4 and ephedra (bronkaid) and still am lethargic all day
DMA was taking RAD with it, so am I. This may be a reason, also im on cardarine . all potential culprits
 
Olympus UK has a lot of interesting stuff I'm interested in, yet vaguely scared of. After reading this thread, Ghar1ne looks interesting. For the least amount of side effects, I assume the best thing to do is dose it near bed, and on an empty stomach? I'm trying to avoid all of those hunger issues/lethargy issues that people are talking of in this thread. Also, in someone who's "younger" (26), would this stuff be useful or not?

Your plan looks solid. However, remember you're probably not going to able to avoid some degree of lethargy, at least for a while.

Yes, MK works even better in younger subjects than it does in older ones.
 
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