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jakecake said:
If u take 400 mgs of nitrates, you would die from blood pressure being so low that your heart would stop. I'm done bro, just keep thinking what you think man. To each their own. I guess you just don't understand, man
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Fixed your post for you since you apparently have zero grammatical skills. For someone so educated you'd think that would come naturally to you
 
Why do they have nitrate free meats because you can die from to much of them also those ncbi studies were done on fish man
 
BamBam0319 said:
Fixed your post for you since you apparently have zero grammatical skills. For someone so educated you'd think that would come naturally to you
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I already told you I'm filling in today for a pharmacist so I'm doing this while counting pills and fill g meds dick
 
jakecake said:
I already told you I'm filling in today for a pharmacist so I'm doing this while counting pills and fill g meds dick
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You type like this every time you're on the forum. Don't make excuses for your lack of grammar skills.
 
jakecake said:
When you take nitrates they don't have to be taken for days before worn off so yes I still think these supps u praise are useless
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I don't understand what you are saying...Viagra is only good for 4 hours max and it does not have to be taken for days to be effective.
 
jakecake said:
Guess this guy has alot of friends that get butt hurt lol my bad I'll leave it alone
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Nope, people just recognize intelligence as well as ignorance. Usually we support the intelligent one, because they make sense. You unfortunately have not made any sense whatsoever since you began this argument. You have yet to provide any evidence to support anything you say and every post you make is hard to read because whole damn thing is a run-on sentence with no discernible punctuation, not to mention your clear confusion between various homophones.
 
jakecake said:
In the end when you can't figure out what's going on to your body what do u do turn to your friends or go on ncbi or go to a ****ing doctor johnny I'll wait bro I'll wait
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You have literally been wrong in almost every single one of your posts. CEE is inferior to monohydrate because it is unstable in low PH environments, which your stomach invariably is. In these environments, it is rapidly converted creatinine, which is not the same as increasing serum creatine levels.

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Serum creatinine was greater in the CEE group compared to the PLA (p = 0.001) and CRT (p = 0.001) groups. Further analysis revealed significant elevations in serum creatinine with the CEE group that occurred days 6 (p = 0.007), 27 (p = 0.005), and 48 (p = 0.005) (Figure 3).


At the end of the day you suggested a selection of products to increase Nitric Oxide, of which only Agmatine does under normal circumstances (unless you have an abnormally elevated levels of arginase, in which then arginine supplementation may actually help).

Organic nitrates are very different from inorganic nitrates. Inorganic are obtainable through the diet and supplementation, whereas organic are medically synthesized. But inorganic nitrates can and do increase NO production.

The central step in bioconversion of nitrate to nitrite is carried out in the oral cavity by bacterial nitrate reductases. As shown here and earlier, ingested or endogenous nitrate is greatly concentrated in saliva, and part of this nitrate is reduced to nitrite locally in the oral cavity [10], [11] and [14]. By this mechanism salivary nitrite levels increase greatly after a nitrate load.

The swallowed nitrite, under the influence of the acidic conditions in the stomach, becomes protonated to nitrous acid View the MathML source(NO2-+H+→HNO2). In turn, a proportion of the nitrous acid decomposes to produce NO and other derivatives; this reaction is further enhanced by low pH, ascorbate and polyphenols [31] and [32]. After the ingestion of nitrate, either in its dietary or medicinal form, there is a sharp rise in the salivary, plasma and urinary levels of nitrate and nitrite

In contrast, inorganic nitrate follows the nitrate–nitrite–NO activation pathway. Nitrite present in the blood stream is reduced directly to NO, a process which is enhanced in hypoxic and acidic conditions, by a number of possible mechanisms, which include haem-proteins [42], myoglobin [43] and [44], xanthine oxidoreductase [45] and [46], endothelial nitric oxide synthase (eNOS) [46], [47] and [48], aldehyde oxidase [49] and [50], ALDH-2 [51], carbonic anhydrase [52], protons [53], ascorbate [31] and polyphenols [32].

The above tells us that inorganic nitrates are more than capable of converting into NO within the body, and that their effects are not biologically inert.

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I can say beets turn nitrate into nitrites in the blood but it isn't nitrate or even a cousin of the elemental family it isn't a nitrate whatsoever show me a study proving me wrong then I'll shut up
 
jakecake said:
Why so but hurt, your friend is being debated and you no likey sorry man didn't know you guys had something going
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Ah yes, resort to "but hurt" and homophobic jibes. I have no issue with anyone being debated, but this hasn't been a debate. You've barely even explained your claims let alone provided evidence to back them up.
 
jakecake said:
I can say beets turn nitrate into nitrites in the blood but it isn't nitrate or even a cousin of the elemental family it isn't a nitrate whatsoever show me a study proving me wrong then I'll shut up
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You have said multiple times that the nitrates I am taking about (found in beets and/or OTC supplements) are useless. They are not. Do I have to go back and find all of the times you said so?
 
Is the issue really showing the compound elevation in bloods though?

Or is it that supplementation with them leads to ergogenic benefit. Because the latter is firmly evidenced.

And other than you and I, not many care about what goes on the middle lol.
 
jakecake said:
I can say beets turn nitrate into nitrites in the blood but it isn't nitrate or even a cousin of the elemental family it isn't a nitrate whatsoever show me a study proving me wrong then I'll shut up
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Show us one study proving anything you're saying is RIGHT. Oh yeah, you won't.
 
jakecake said:
I can say beets turn nitrate into nitrites in the blood but it isn't nitrate or even a cousin of the elemental family it isn't a nitrate whatsoever show me a study proving me wrong then I'll shut up
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It is an inorganic nitrate. What more do you need to know?

It converts into Nitrite in the oral cavity, which then converts into NO, which is the desired end product.
 
Driven2lift said:
Is the issue really showing the compound elevation in bloods though?

Or is it that supplementation with them leads to ergogenic benefit. Because the latter is firmly evidenced.

And other than you and I, not many care about what goes on the middle lol.
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These nitrates we're talking to elevate plasma nitrate, lower blood pressure, and provide endurance/performance benefits. What else could you want from nitrates? Apparently this guy compares them to tren...
 
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muscleupcrohn said:
These nitrates we're talking to elevate plasma nitrate, lower blood pressure, and provide endurance/performance benefits. What else could you want from nitrates? Apparently this guy compares them to tren...
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Couldn't want much else.
Further Carryover to heart health, and a longer half-life would be nice.

Maybe one day
 
muscleupcrohn said:
These nitrates we're talking to elevate plasma nitrate, lower blood pressure, and provide endurance/performance benefits. What else could you want from nitrates? Apparently this guy compares them to tren...
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Dude idk why preworkouts are even a thing. Why doesn't everyone just pop some dbol and jab some tren base into whatever muscle they're training that day? Doesn't make sense to me. Tren is just so much more effective.
 
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muscleupcrohn said:
You have said multiple times that the nitrates I am taking about (found in beets and/or OTC supplements) are useless. They are not. Do I have to go back and find all of the times you said so?
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I said useless compared to actually nitrates is all and the evidence is there loom it up Creatine nitrate is in no way a nitrate an looking it up you'll notice there have been no studies providing evidence that it is
 
jakecake said:
I said useless compared to actually nitrates is all and the evidence is there loom it up Creatine nitrate is in no way a nitrate an looking it up you'll notice there have been no studies providing evidence that it is
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do you have studies proving its not?
 
All I was trying to say this whole time is there is a big difference from a supplement nitrate and a ex nitrate all Creatine nitrate does is take kno3 and make it no2 that is it no nitrates are involved unless in blood plasma were nitrates already are all the time
 
jakecake said:
All I was trying to say this whole time is there is a big difference from a supplement nitrate and a ex nitrate all Creatine nitrate does is take kno3 and make it no2 that is it no nitrates are involved unless in blood plasma were nitrates already are all the time
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Supp not ex
 
Driven2lift said:
Is the issue really showing the compound elevation in bloods though?

Or is it that supplementation with them leads to ergogenic benefit. Because the latter is firmly evidenced.

And other than you and I, not many care about what goes on the middle lol.
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Nope it doesn't that's what I'm trying to say
 
Trying to read his posts makes my head start to hurt
 
ni·trate

noun

CHEMISTRY

plural noun:*nitrates

ˈnītrāt/

1.

a salt or ester of nitric acid, containing the anion NO3−*or the group —NO3unless your Creatine somehow has prescribed nitric acid in it it isn't a nitrate I rest my case
 
jakecake said:
ni·trate

noun

CHEMISTRY

plural noun:*nitrates

ˈnītrāt/

1.

a salt or ester of nitric acid, containing the anion NO3−*or the group —NO3unless your Creatine somehow has prescribed nitric acid in it it isn't a nitrate I rest my case
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Applicants have cost-effectively synthesized Creatine Nitrate by combining nitric acid and Creatine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Creatine Dinitrate or Creatine Trinitrate. An alternative implementation may comprise using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Creatine Nitrite. Creatine Nitrite has the same effects as Creatine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Creatine Nitrate-Orotate.
 
So now I'm confused everything I read online ncbi and examine ect are all contradicting **** it if it works for you take it
 
Adizzle1 said:
Applicants have cost-effectively synthesized Creatine Nitrate by combining nitric acid and Creatine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Creatine Dinitrate or Creatine Trinitrate. An alternative implementation may comprise using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Creatine Nitrite. Creatine Nitrite has the same effects as Creatine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Creatine Nitrate-Orotate.
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Creatine nitrate has the same effects as Creatine nitrate ??
 
jakecake said:
So now I'm confused everything I read online ncbi and examine ect are all contradicting **** it if it works for you take it
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So do you actually want to have a discussion? Have you read the studies I referenced? The creatine nitrate study does a decent job showing that the benefits observed were not solely the result of creatine, since in addition to a placebo group and 2 doses of CrN, there was a creatine monohydrate group as well. The nitrates did something; in this case, improved training volume and serum nitrate compared to placebo and creatine alone.
 
I guess the study I read was that a certain brands of supps said it was Creatine nitrate but when tested didn't have any nitrate salts in it it had potassium nitrate Wich I have taken at quadruple the dose an didn't notice any more pump the. Usuall
 
jakecake said:
Creatine nitrate has the same effects as Creatine nitrate ??
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Applicants have cost-effectively synthesized Creatine Nitrate by combining nitric acid and Creatine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Creatine Dinitrate or Creatine Trinitrate. An alternative implementation may comprise using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Creatine Nitrite. Creatine Nitrite has the same effects as Creatine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Creatine Nitrate-Orotate.
 
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