RBC

thebigt

thebigt

Legend
any suggestions other than donating blood to get/keep RBC down?
 
Yes.

First off, when you do give blood, look into a "power red" or "double red".

Stay hydrated every day. Body weight/2 = minimum number of ounces of water to be consumed.

Here are some possible supplements that may (or may not) help and that you may want to research:

• DMB/Naringen/Grapefruit
• Inositol Hexaphosphate (IP6)
• Alpha Lipoic Acid
• Green Tea/Green Tea Extract
• Losartan (prescribed pharma product)
• Tyrosine (possibly, but without its co-factors B6 and C)
• Vitamin K2 (MK7)
• Nattokinase
• Quercetin
• Curcumin
• Citrulline Malate

Avoid excessive red meat, iron and NAC.
 
I tried the • DMB/Naringen/Grapefruit with no luck ??
 
Do you know why it is high? Anything else out of range?
 
HIT4ME said:
Do you know why it is high? Anything else out of range?
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everything else is good...my rbc has run high for last 4 years, been on trt for around 12 years now. my dose of trt was cut in half 4 years ago due to polycythemia and now it is starting to creep up again-last bloods it was slightly above range but up from the previous bloods.
 
Hmmm, my general feeling would be to try drinking more water to start and get retested. You could just be dehydrated if all of the other values on the cbc are normal.

Do you have any other symptoms? Phlebotomy is the surefire way to reduce levels if you are having symptoms.

In other words - if you have no sides I wouldn't worry too much and woukdn't mess with more supplements that could make things harder to diagnose. Just keep going, increase water intake and check again.

If you are having sides, I wouldn't mess with supplements right now and would go get blood drawn.

I would also rule out sleep apnea of course, but obviously when on TRT everyone jumps to that. Not sure why it would creep back up if you had it all normalized though for a while. But you can find a works with things I don't know.
 
HIT4ME said:
Hmmm, my general feeling would be to try drinking more water to start and get retested. You could just be dehydrated if all of the other values on the cbc are normal.

Do you have any other symptoms? Phlebotomy is the surefire way to reduce levels if you are having symptoms.

In other words - if you have no sides I wouldn't worry too much and woukdn't mess with more supplements that could make things harder to diagnose. Just keep going, increase water intake and check again.

If you are having sides, I wouldn't mess with supplements right now and would go get blood drawn.

I would also rule out sleep apnea of course, but obviously when on TRT everyone jumps to that. Not sure why it would creep back up if you had it all normalized though for a while. But you can find a works with things I don't know.
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I've been using a cpap machine for several years now...no symptoms at all-just worried my trt dose might get cut again--I've went from 200mg weekly down to 100mg weekly already.
 
Naringin has been recommended by several members in my TRT group for controlling RBC/Hematocrit. Several have sworn by it.
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kenpoengineer said:
Naringin has been recommended by several members in my TRT group for controlling RBC/Hematocrit. Several have sworn by it.
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Worth a try !
 
kenpoengineer said:
Naringin has been recommended by several members in my TRT group for controlling RBC/Hematocrit. Several have sworn by it.
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thanks, it looks like something to try...cheap fix if it works!!!
 
thebigt said:
flavone found in grapefruit...been using it for awhile now to enhance absorption in supplements
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Agreed, I've used the same product (I just ran out). I can't find it in bulk powder ...

[Edit - I just did: Invalid Link Removed]

You may also want to try bioperine (black pepper extract) as an absorption enhancer.
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Beau said:
Agreed, I've used the same product (I just ran out). I can't find it in bulk powder ...

You may also want to try bioperine (black pepper extract) as an absorption enhancer.
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Piperine you mean? That's something I always look for with my tumeric curcumin supplements
 
Smont said:
Piperine you mean? That's something I always look for with my tumeric curcumin supplements
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Yes. Piperine (from black pepper) can enhance the absorption or bioavailability of certain compounds. Bioperine is a branded extract of black pepper which is 95% piperine, meaning it is standardized to minimum 95% piperine.
 
Beau said:
Yes. Piperine (from black pepper) can enhance the absorption or bioavailability of certain compounds. Bioperine is a branded extract of black pepper which is 95% piperine, meaning it is standardized to minimum 95% piperine.
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Ya, black pepper extract, it's a ingredient I'm always happy to see included in stuff
 
ironkill said:
I've read that piperine can wreak havoc on your gut lining and poke holes in it?
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I think you got some bad information .....................
 
Regarding citrus bioflavonoids, are you guys concerned with oral bioavailability? I wonder how useful it would be to take citrus bioflavonoids, such as the ones mentioned in this thread, alongside a glass of OJ to enhance absorption? Idk.. just a thought... maybe a wrong one. I’m no expert in pharmacokinetics :)

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aaronuconn said:
Regarding citrus bioflavonoids, are you guys concerned with oral bioavailability? I wonder how useful it would be to take citrus bioflavonoids, such as the ones mentioned in this thread, alongside a glass of OJ to enhance absorption? Idk.. just a thought... maybe a wrong one. I’m no expert in pharmacokinetics :)

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grapefruit juice would enhance absorption more than OJ.
 
thebigt said:
grapefruit juice would enhance absorption more than OJ.
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Are you referencing grapefruit juice because of the CYP3A4 inhibition? While you may be correct, I was referencing absorption may, theoretically, possibly, be better if it’s consumed with other citrus bioflavonoids. I have no reason to believe this, other than a thought that the flavonoids may act synergistically with each other. Seems like flavonoids consumed individually have poor bioavailability. They might do better when consumed together with a citrus fruit juice or an orange for example. Or a grapefruit!

Idk. Just a thought.
 
Smont said:
Seeing how it's actually good for your stomach and promotes gut health I highly doubt it
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It can alter permeability of the lining which could cause issues. Also be weary of consuming with other drugs. Prob not an issue for most but still rather use other absorption compounds
 
aaronuconn said:
Are you referencing grapefruit juice because of the CYP3A4 inhibition? While you may be correct, I was referencing absorption may, theoretically, possibly, be better if it’s consumed with other citrus bioflavonoids. I have no reason to believe this, other than a thought that the flavonoids may act synergistically with each other. Seems like flavonoids consumed individually have poor bioavailability. They might do better when consumed together with a citrus fruit juice or an orange for example. Or a grapefruit!

Idk. Just a thought.
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some prescription drugs specifically warn against grapefruit juice because of increasing absorption--I know for a fact if I drink a glass of grapefruit juice with a Viagra effect is much increased and I only need a quarter[25mg]of a 100mg tab to get effective results-this is great because I only get 12 100mg tabs every 3 months.
 
thebigt said:
some prescription drugs specifically warn against grapefruit juice because of increasing absorption--I know for a fact if I drink a glass of grapefruit juice with a Viagra effect is much increased and I only need a quarter[25mg]of a 100mg tab to get effective results-this is great because I only get 12 100mg tabs every 3 months.
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Yep, I get what you mean now. We were just talking about absorption in two different ways/mechanisms.
 
aaronuconn said:
Yep, I get what you mean now. We were just talking about absorption in two different ways/mechanisms.
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glad we are on same page, I might have misunderstood your post. sometimes it's hard to get the full meaning when posting on the internet.
 
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